Recent Trends in Food Applications of Antioxidants

Enzyme-Triggered Hydrogels for Pharmaceutical and Food Applications

Research Advancements in Pharmaceutical, Nutritional, and Industrial Enzymology - Advances in Medical Technologies and Clinical Practice ◽

10.4018/978-1-5225-5237-6.ch008 ◽

2018 ◽

pp. 159-177

Author(s):

Lakshmishri Upadrasta ◽

Vijay Kumar Garlapati ◽

Nafisa Lakdawala ◽

Rintu Banerjee

Keyword(s):

Free Radicals ◽

Horseradish Peroxidase ◽

Significant Role ◽

Physiological Conditions ◽

Polymeric Hydrogel ◽

Hydrogel Formation ◽

Food Applications ◽

Recent Trends ◽

Polymeric Hydrogels

Enzyme-mediated polymeric hydrogels are drawing considerable attention in pharmaceutical and food sectors owing to their superior biocompatibility and process controllability under physiological conditions. Enzymes play a significant role in polymeric hydrogel formation through different mechanisms. Oxidases (e.g., horseradish peroxidase and tyrosinase) have demonstrated to drive the crosslinking of gel precursors by oxidizing the phenolic or acrylic moieties to free radicals. Transferases and hydrolases catalyze elongation of biopolymer chains which gradually self-assemble into hydrogels. Still more certain enzymes also participate in hydrogel formation by releasing gelation factors. Enhancement of the desired properties of certain hydrogels through the interior and exterior post-modifications has also been demonstrated by certain enzymes. Hence, in this chapter, the authors explore the different mechanisms of enzyme-mediated hydrogels preparations and its fabrication towards pharmaceutical and food sectors along with the discussion of recent trends and further prospects.

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Enzyme-Triggered Hydrogels for Pharmaceutical and Food Applications

10.4018/978-1-6684-3546-5.ch057 ◽

2022 ◽

pp. 1203-1221

Author(s):

Lakshmishri Upadrasta ◽

Vijay Kumar Garlapati ◽

Nafisa Lakdawala ◽

Rintu Banerjee

Keyword(s):

Free Radicals ◽

Horseradish Peroxidase ◽

Significant Role ◽

Physiological Conditions ◽

Polymeric Hydrogel ◽

Hydrogel Formation ◽

Food Applications ◽

Recent Trends ◽

Polymeric Hydrogels

Enzyme-mediated polymeric hydrogels are drawing considerable attention in pharmaceutical and food sectors owing to their superior biocompatibility and process controllability under physiological conditions. Enzymes play a significant role in polymeric hydrogel formation through different mechanisms. Oxidases (e.g., horseradish peroxidase and tyrosinase) have demonstrated to drive the crosslinking of gel precursors by oxidizing the phenolic or acrylic moieties to free radicals. Transferases and hydrolases catalyze elongation of biopolymer chains which gradually self-assemble into hydrogels. Still more certain enzymes also participate in hydrogel formation by releasing gelation factors. Enhancement of the desired properties of certain hydrogels through the interior and exterior post-modifications has also been demonstrated by certain enzymes. Hence, in this chapter, the authors explore the different mechanisms of enzyme-mediated hydrogels preparations and its fabrication towards pharmaceutical and food sectors along with the discussion of recent trends and further prospects.

Download Full-text