Blood donor screening for HIV infection: introduction in the United Kingdom and Europe and its impact on transfusion medicine

Author(s):  
D. B. L. McClelland
1995 ◽  
Vol 6 (4) ◽  
pp. 284-286 ◽  
Author(s):  
Philip R Fischer ◽  
Remy M Toko

Summary: Despite high seroprevalence rates in some parts of Africa, there is notable variation in prevalence between population subgroups. To document changes and trends in HIV seroprevalence in northeastern Zaire, 1989 to 1992 blood donor data were reviewed. Overall, 2453 donors were tested with seropositivity varying from 2.8% in 1989 to 6.9% in 1992. The increase in seropositivity was significant for men (2.5 to 5.8%, P = 0.017) and for people residing in rural areas (2.0 to 6.1%, P = 0.0008) but not for women (5.4 to 8.6%, P = 0.15) nor for urban individuals (10.5 to 8.6%, P = 0.55). These findings suggest that: 1) HIV infection is spreading in previously less-affected population subgroups rather than increasing widely in the entire population, 2) the HIV epidemic could be reaching a plateau or endemic phase in northeastern Zaire, and, 3) continued blood donor screening and wise transfusion practices are needed.


Vox Sanguinis ◽  
1995 ◽  
Vol 68 (4) ◽  
pp. 251-252 ◽  
Author(s):  
H. Vrielink ◽  
C.L. Poel ◽  
H.W. Reesink

2021 ◽  
Author(s):  
Emily C. Jeanes ◽  
Michaela L. Wegg ◽  
Judy A. Mitchell ◽  
Simon L. Priestnall ◽  
Lorraine Fleming ◽  
...  

1999 ◽  
Vol 123 (8) ◽  
pp. 672-676
Author(s):  
Ronald A. Sacher ◽  
S. Gerald Sandler

Abstract The final decade of the last century of the second millennium ad has seen dramatic changes in all aspects of science and health care. In transfusion medicine, the blood supply is the safest it has ever been. Newer refinements and innovations are continuously being researched and implemented to achieve and further enhance safety. Advances in blood conservation, pharmacologic manipulation, engineered blood derivatives, and recombinant growth factors can now provide safer and more effective alternatives to blood transfusions for many patients. This overview highlights selective innovations in transfusion medicine and emphasizes some significant advances that have occurred in blood donor screening, blood component collections and therapy, and laboratory testing. Newer technologies are anticipated that will further enhance the safety of blood and transfusions and potentially augment annually the blood supply on a worldwide basis.


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