TOF-SIMS Imaging of Lipids on Rat Brain Sections

2014 ◽  
pp. 21-27 ◽  
Author(s):  
David Touboul ◽  
Alain Brunelle
Keyword(s):  
Rat Brain ◽  
Tof Sims

scholarly journals Impact of Inhaled Nitric Oxide on the Sulfatide Profile of Neonatal Rat Brain Studied by TOF-SIMS Imaging

2014 ◽  
Vol 15 (4) ◽  
pp. 5233-5245 ◽  
Author(s):  
Hanane Kadar ◽  
Hoa Pham ◽  
David Touboul ◽  
Alain Brunelle ◽  
Olivier Baud
Keyword(s):  
Nitric Oxide ◽  
Rat Brain ◽  
Inhaled Nitric Oxide ◽  
Neonatal Rat ◽  
Tof Sims ◽  
Neonatal Rat Brain

Evaluation of biomolecular distributions in rat brain tissues by means of ToF-SIMS using a continuous beam of Ar clusters

2016 ◽  
Vol 11 (2) ◽  
pp. 02A307 ◽  
Author(s):  
Shusuke Nakano ◽  
Yuta Yokoyama ◽  
Satoka Aoyagi ◽  
Naoyuki Himi ◽  
John S. Fletcher ◽  
...  
Keyword(s):  
Rat Brain ◽  
Continuous Beam ◽  
Tof Sims ◽  
Brain Tissues

Mass spectrometry imaging of rat brain sections: nanomolar sensitivity with MALDI versus nanometer resolution by TOF–SIMS

2009 ◽  
Vol 396 (1) ◽  
pp. 151-162 ◽  
Author(s):  
Farida Benabdellah ◽  
Alexandre Seyer ◽  
Loïc Quinton ◽  
David Touboul ◽  
Alain Brunelle ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Rat Brain ◽  
Mass Spectrometry Imaging ◽  
Nanometer Resolution ◽  
Tof Sims

Compatibility between TOF-SIMS lipid imaging and histological staining on a rat brain section

2012 ◽  
Vol 45 (1) ◽  
pp. 260-263 ◽  
Author(s):  
C. Bich ◽  
S. Vianello ◽  
V. Guérineau ◽  
D. Touboul ◽  
S. De La Porte ◽  
...  
Keyword(s):  
Rat Brain ◽  
Brain Section ◽  
Tof Sims ◽  
Histological Staining

Applications of Time-OF-Flight Secondary Ion Mass Spectrometry (TOF-SIMS)

1990 ◽  
Vol 48 (2) ◽  
pp. 308-309
Author(s):  
Bruno Schueler ◽  
Robert W. Odom
Keyword(s):  
Mass Spectrometry ◽  
Secondary Ion Mass Spectrometry ◽  
Structural Information ◽  
Time Of Flight ◽  
Biological Tissues ◽  
Polymer Surfaces ◽  
Tof Sims ◽  
Secondary Ions ◽  
Ion Mass Spectrometry ◽  
Secondary Ion

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) provides unique capabilities for elemental and molecular compositional analysis of a wide variety of surfaces. This relatively new technique is finding increasing applications in analyses concerned with determining the chemical composition of various polymer surfaces, identifying the composition of organic and inorganic residues on surfaces and the localization of molecular or structurally significant secondary ions signals from biological tissues. TOF-SIMS analyses are typically performed under low primary ion dose (static SIMS) conditions and hence the secondary ions formed often contain significant structural information.This paper will present an overview of current TOF-SIMS instrumentation with particular emphasis on the stigmatic imaging ion microscope developed in the authors’ laboratory. This discussion will be followed by a presentation of several useful applications of the technique for the characterization of polymer surfaces and biological tissues specimens. Particular attention in these applications will focus on how the analytical problem impacts the performance requirements of the mass spectrometer and vice-versa.

cDNA cloning and expression of a gamma-aminobutyric acidA receptor epsilon-subunit in rat brain

2000 ◽  
Vol 12 (12) ◽  
pp. 4318-4330 ◽  
Author(s):  
Nathalie Moragues ◽  
Philippe Ciofi ◽  
Pierrette Lafon ◽  
Marie-Francoise Odessa ◽  
Gerard Tramu ◽  
...  
Keyword(s):  
Rat Brain ◽  
Cdna Cloning ◽  
Cloning And Expression ◽  
Epsilon Subunit

Antisense knockdown of the glial glutamate transporter GLT-1 exacerbates hippocampal neuronal damage following traumatic injury to rat brain

2001 ◽  
Vol 13 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Vemuganti L. Raghavendra Rao ◽  
Aclan Dogan ◽  
Kellie K. Bowen ◽  
Kathryn G. Todd ◽  
Robert J. Dempsey
Keyword(s):  
Rat Brain ◽  
Neuronal Damage ◽  
Traumatic Injury ◽  
Glutamate Transporter ◽  
Glial Glutamate Transporter ◽  
Antisense Knockdown

Inhibition of Rat Brain Monoamine Oxidase Activities by Psoralen and Isopsoralen: Implications for the Treatment of Affective Disorders

2001 ◽  
Vol 88 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Ling Dong Kong ◽  
Ren Xiang Tan ◽  
Anthony Yiu Ho Woo ◽  
Christopher Hon Ki Cheng2Note
Keyword(s):  
Monoamine Oxidase ◽  
Rat Brain ◽  
Affective Disorders ◽  
Brain Monoamine
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