A Culture Model to Study Neuron-Schwann Cell-Astrocyte Interactions

2018 ◽  
pp. 269-279 ◽  
Author(s):  
Susana R. Cerqueira ◽  
Yee-Shuan Lee ◽  
Mary Bartlett Bunge
Keyword(s):  
Schwann Cell ◽  
Culture Model

Human Neurofibromas in Co-Culture with Mouse Neurons

1982 ◽  
Vol 40 ◽  
pp. 194-195
Author(s):  
R.L. Martuza ◽  
T. Liszczak ◽  
A. Okun ◽  
T-Y Wang
Keyword(s):  
Schwann Cell ◽  
Schwann Cells ◽  
Genetic Disorder ◽  
Cranial Nerves ◽  
Sympathetic Nerves ◽  
Acoustic Neuromas ◽  
Spinal Roots ◽  
Neural Crest Origin ◽  
Multiple Abnormalities ◽  
Other Neoplasms

Neurofibromatosis (NF) is an autosomal dominant genetic disorder with a prevalence of 1/3,000 births. The NF mutation causes multiple abnormalities of various cells of neural crest origin. Schwann cell tumors (neurofibromas, acoustic neuromas) are the most common feature of neurofibromatosis although meningiomas, gliomas, and other neoplasms may be seen. The schwann cell tumors commonly develop from the schwann cells associated with sensory or sympathetic nerves or their ganglia. Schwann cell tumors on ventral spinal roots or motor cranial nerves are much less common. Since the sensory neuron membrane is known to contain a mitogenic factor for schwann cells, we have postulated that neurofibromatosis may be due to an abnormal interaction between the nerve and the schwann cell and that this interaction may be hormonally modulated. To test this possibility a system has been developed in which an enriched schwannoma cell culture can be obtained and co-cultured with pure neurons.

1120: Citrate and Vitamin E Blunt the SWL-Induced Free Radical Surge in an In-Vitro MDCK Cell Culture Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 295-295
Author(s):  
Fernando C. Delvecchio ◽  
Ricardo M. Brizuela ◽  
Karen J. Byer ◽  
W. Patrick Springhart ◽  
Saeed R. Khan ◽  
...  
Keyword(s):  
Cell Culture ◽  
Free Radical ◽  
Vitamin E ◽  
Mdck Cell ◽  
Cell Culture Model ◽  
Culture Model

Ovarian carcinoma explant culture: model development and application in drug testing

2016 ◽  
Vol 76 (10) ◽  
Author(s):  
M Suarez-Carmona ◽  
A Heinzelmann ◽  
M Hampel ◽  
S Schott ◽  
I Zörnig ◽  
...  
Keyword(s):  
Ovarian Carcinoma ◽  
Drug Testing ◽  
Model Development ◽  
Explant Culture ◽  
Culture Model

Determination of anti-oxidative effects of phytogenic substances using a porcine epithelial cell culture model

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
T Kaschubek ◽  
E Mayer ◽  
G Schatzmayr ◽  
K Teichmann
Keyword(s):  
Cell Culture ◽  
Epithelial Cell ◽  
Cell Culture Model ◽  
Epithelial Cell Culture ◽  
Culture Model ◽  
Oxidative Effects
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