Enhanced Manipulation of Human Mitochondrial DNA Heteroplasmy In Vitro Using Tunable mtZFN Technology

Methods in Molecular Biology - Zinc Finger Proteins ◽

10.1007/978-1-4939-8799-3_4 ◽

2018 ◽

pp. 43-56 ◽

Cited By ~ 5

Author(s):

Payam A. Gammage ◽

Michal Minczuk

Keyword(s):

Mitochondrial Dna ◽

Human Mitochondrial Dna ◽

Mitochondrial Dna Heteroplasmy

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Identification and in vitro capping of a primary transcript of human mitochondrial DNA.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)43183-8 ◽

1984 ◽

Vol 259 (6) ◽

pp. 3909-3915 ◽

Cited By ~ 5

Author(s):

B K Yoza ◽

D F Bogenhagen

Keyword(s):

Mitochondrial Dna ◽

Primary Transcript ◽

Human Mitochondrial Dna ◽

In Vitro Capping

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Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo

Scientific Reports ◽

10.1038/s41598-018-20064-2 ◽

2018 ◽

Vol 8 (1) ◽

Cited By ~ 14

Author(s):

Oliver M. Russell ◽

Isabelle Fruh ◽

Pavandeep K. Rai ◽

David Marcellin ◽

Thierry Doll ◽

...

Keyword(s):

Mitochondrial Dna ◽

Mitochondrial Dna Deletion ◽

Human Mitochondrial Dna ◽

Dna Deletion ◽

Preferential Amplification

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Questioning the prevalence and reliability of human mitochondrial DNA heteroplasmy from massively parallel sequencing data

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1413478111 ◽

2014 ◽

Vol 111 (43) ◽

pp. E4546-E4547 ◽

Cited By ~ 11

Author(s):

R. S. Just ◽

J. A. Irwin ◽

W. Parson

Keyword(s):

Mitochondrial Dna ◽

Massively Parallel Sequencing ◽

Massively Parallel ◽

Sequencing Data ◽

Human Mitochondrial Dna ◽

Parallel Sequencing ◽

Mitochondrial Dna Heteroplasmy

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In vitro replication of human mitochondrial DNA: Accurate initiation at the origin of light-strand synthesis

Cell ◽

10.1016/0092-8674(85)90291-0 ◽

1985 ◽

Vol 42 (3) ◽

pp. 951-958 ◽

Cited By ~ 107

Author(s):

Tai Wai Wong ◽

David A. Clayton

Keyword(s):

Mitochondrial Dna ◽

Human Mitochondrial Dna ◽

In Vitro Replication ◽

Light Strand

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Engineered mtZFNs for Manipulation of Human Mitochondrial DNA Heteroplasmy

Methods in Molecular Biology - Mitochondrial DNA ◽

10.1007/978-1-4939-3040-1_11 ◽

2016 ◽

pp. 145-162 ◽

Cited By ~ 19

Author(s):

Payam A. Gammage ◽

Lindsey Van Haute ◽

Michal Minczuk

Keyword(s):

Mitochondrial Dna ◽

Human Mitochondrial Dna ◽

Mitochondrial Dna Heteroplasmy

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Evidence for a direct role of the DNA polymerase gamma in the replication of the human mitochondrial DNA in vitro

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(87)90767-4 ◽

1987 ◽

Vol 146 (3) ◽

pp. 1146-1153 ◽

Cited By ~ 22

Author(s):

Patrick Lestienne

Keyword(s):

Mitochondrial Dna ◽

Dna Polymerase ◽

Direct Role ◽

Human Mitochondrial Dna ◽

Polymerase Gamma ◽

Dna Polymerase Gamma

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Introduction of "Nicks" and "Chops" into Human Mitochondrial DNA in vivo and in vitro

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1973.tb02659.x ◽

1973 ◽

Vol 33 (1) ◽

pp. 98-103 ◽

Cited By ~ 8

Author(s):

Jurgen Koch

Keyword(s):

Mitochondrial Dna ◽

Human Mitochondrial Dna

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Inter- and intragenerational transmission of a human mitochondrial DNA heteroplasmy among 13 maternally-related individuals and differences between and within tissues in two family members

Mitochondrion ◽

10.1016/s1567-7249(03)00028-x ◽

2003 ◽

Vol 2 (6) ◽

pp. 401-414 ◽

Cited By ~ 22

Author(s):

Kazumasa Sekiguchi ◽

Kentaro Kasai ◽

Barbara C Levin

Keyword(s):

Mitochondrial Dna ◽

Family Members ◽

Human Mitochondrial Dna ◽

Related Individuals ◽

Mitochondrial Dna Heteroplasmy

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In vitro transcription of human mitochondrial DNA: accurate termination requires a region of DNA sequence that can function bidirectionally.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.83.17.6277 ◽

1986 ◽

Vol 83 (17) ◽

pp. 6277-6281 ◽

Cited By ~ 42

Author(s):

T. W. Christianson ◽

D. A. Clayton

Keyword(s):

Mitochondrial Dna ◽

Dna Sequence ◽

In Vitro Transcription ◽

Human Mitochondrial Dna

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In vitro transcription of human mitochondrial DNA. Identification of specific light strand transcripts from the displacement loop region.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)33188-0 ◽

1983 ◽

Vol 258 (2) ◽

pp. 1268-1275 ◽

Cited By ~ 4

Author(s):

M W Walberg ◽

D A Clayton

Keyword(s):

Mitochondrial Dna ◽

In Vitro Transcription ◽

Dna Identification ◽

Human Mitochondrial Dna ◽

Loop Region ◽

Light Strand

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