Quantitative Analysis of Stall of Replicating DNA Polymerase by G-Quadruplex Formation

2019 ◽  
pp. 257-274
Author(s):  
Shuntaro Takahashi ◽  
Naoki Sugimoto
Keyword(s):  
Quantitative Analysis ◽  
Dna Polymerase ◽  
G Quadruplex ◽  
Quadruplex Formation

scholarly journals DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation

2013 ◽  
Vol 41 (22) ◽  
pp. 10323-10333 ◽  
Author(s):  
Justin D. Lormand ◽  
Noah Buncher ◽  
Connor T. Murphy ◽  
Parminder Kaur ◽  
Marietta Y. Lee ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Dna Polymerase Δ ◽  
G Quadruplex ◽  
Quadruplex Formation ◽  
Lagging Strand

scholarly journals TGF‐β‐induced fibrotic stress increases G‐quadruplex formation in human fibroblasts

FEBS Letters ◽  
2019 ◽  
Vol 593 (22) ◽  
pp. 3149-3161 ◽  
Author(s):  
Priyanka Toshniwal ◽  
Michelle Nguyen ◽  
Aurore Guédin ◽  
Helena Viola ◽  
Diwei Ho ◽  
...  
Keyword(s):  
Human Fibroblasts ◽  
G Quadruplex ◽  
Quadruplex Formation

TT Dimerization and Its Effect on Human Telomere G-Quadruplex Formation

2015 ◽  
Vol 36 (6) ◽  
pp. 1729-1732
Author(s):  
In Sun Kim ◽  
Young Jun Seo
Keyword(s):  
G Quadruplex ◽  
Quadruplex Formation ◽  
Human Telomere

Inhibition of Protein Synthesis Through RNA-Based Tandem G-Quadruplex Formation

2021 ◽  
Author(s):  
Masaki Hagihara
Keyword(s):  
Protein Synthesis ◽  
Reverse Transcriptase ◽  
Repeat Sequences ◽  
Guanine Quadruplex ◽  
G Quadruplex ◽  
Inhibition Of Protein Synthesis ◽  
Quadruplex Formation

Tandem guanine repeat sequences can adopt guanine quadruplex (G-quadruplex) structures and consecutive guanine repeat sequences can potentially afford multiple G-quadruplex structures. By using a reverse transcriptase stop assay and biophysical...

scholarly journals Structure and Stability of a Dimeric G-Quadruplex Formed by Cyclic Oligonucleotides

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Joan Casals ◽  
Júlia Viladoms ◽  
Enrique Pedroso ◽  
Carlos González
Keyword(s):  
Telomeric Repeat ◽  
High Melting ◽  
Structure And Stability ◽  
Dimeric Structure ◽  
Nmr Data ◽  
High Melting Temperature ◽  
Sodium Nmr ◽  
G Quadruplex ◽  
Global Topology ◽  
Quadruplex Formation

We have studied the structure and stability of the cyclic dodecamer d<pGGGTTAGGGTTA>, containing two copies of the human telomeric repeat. In the presence of sodium, NMR data are consistent with a dimeric structure of the molecule in which two cycles self-associate forming a quadruplex with three guanine tetrads connected by edgewise loops. The two macrocycles are arranged in a parallel way, and the dimeric structure exhibits a high melting temperature. These results indicate that cyclization of the phosphodiester chain does not prevent quadruplex formation, although it affects the global topology of the quadruplex.

scholarly journals Mutagenesis Reveals an Unusual Combination of Guanines in RNA G-Quadruplex Formation

ACS Omega ◽  
2017 ◽  
Vol 2 (8) ◽  
pp. 4790-4799
Author(s):  
Prachi Agarwala ◽  
Gargi Pal ◽  
Satyaprakash Pandey ◽  
Souvik Maiti
Keyword(s):  
G Quadruplex ◽  
Unusual Combination ◽  
Quadruplex Formation

scholarly journals A Minimal Sequence for Left‐Handed G‐Quadruplex Formation

2019 ◽  
Vol 58 (8) ◽  
pp. 2331-2335 ◽  
Author(s):  
Blaž Bakalar ◽  
Brahim Heddi ◽  
Emmanuelle Schmitt ◽  
Yves Mechulam ◽  
Anh Tuân Phan
Keyword(s):  
Left Handed ◽  
G Quadruplex ◽  
Quadruplex Formation ◽  
Minimal Sequence

scholarly journals A Minimal Sequence for Left-Handed G-Quadruplex Formation

2019 ◽  
Vol 131 (8) ◽  
pp. 2353-2357 ◽  
Author(s):  
Blaž Bakalar ◽  
Brahim Heddi ◽  
Emmanuelle Schmitt ◽  
Yves Mechulam ◽  
Anh Tuân Phan
Keyword(s):  
Left Handed ◽  
G Quadruplex ◽  
Quadruplex Formation ◽  
Minimal Sequence
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