Display of Antibody Chains on Filamentous Bacteriophage

Author(s):  
Peter Jones
1966 ◽  
Vol 25 (3) ◽  
pp. 275-284 ◽  
Author(s):  
George Fareed ◽  
Karin A. Ippen ◽  
Raymond C. Valentine

1996 ◽  
Vol 93 (15) ◽  
pp. 7761-7766 ◽  
Author(s):  
I. Fisch ◽  
R. E. Kontermann ◽  
R. Finnern ◽  
O. Hartley ◽  
A. S. Soler-Gonzalez ◽  
...  

2006 ◽  
Vol 361 (2) ◽  
pp. 209-215 ◽  
Author(s):  
Ying A. Wang ◽  
Xiong Yu ◽  
Stacy Overman ◽  
Masamichi Tsuboi ◽  
George J. Thomas ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Luciana D’Apice ◽  
Valerio Costa ◽  
Rossella Sartorius ◽  
Maria Trovato ◽  
Marianna Aprile ◽  
...  

The filamentous bacteriophage fd, codisplaying antigenic determinants and a single chain antibody fragment directed against the dendritic cell receptor DEC-205, is a promising vaccine candidate for its safety and its ability to elicit innate and adaptive immune response in absence of adjuvants. By using a system vaccinology approach based on RNA-Sequencing (RNA-Seq) analysis, we describe a relevant gene modulation in dendritic cells pulsed with anti-DEC-205 bacteriophages fd. RNA-Seq data analysis indicates that the bacteriophage fd virions are sensed as a pathogen by dendritic cells; they activate the danger receptors that trigger an innate immune response and thus confer a strong adjuvanticity that is needed to obtain a long-lasting adaptive immune response.


1991 ◽  
Vol 220 (2) ◽  
pp. 359-379 ◽  
Author(s):  
Raman Nambudripad ◽  
Wilhelm Stark ◽  
Lee Makowski

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