End-Stage Congestive Heart Failure: Ventricular Assist Devices

2009 ◽  
pp. 605-612
Author(s):  
Kenneth K. Liao ◽  
Ranjit John
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Assist Devices ◽  
End Stage

scholarly journals Sex Differences in Patients Receiving Left Ventricular Assist Devices for End-Stage Heart Failure

2020 ◽  
Vol 8 (9) ◽  
pp. 770-779
Author(s):  
Jadry Gruen ◽  
Cesar Caraballo ◽  
P. Elliott Miller ◽  
Megan McCullough ◽  
Catherine Mezzacappa ◽  
...  
Keyword(s):  
Heart Failure ◽  
Sex Differences ◽  
Left Ventricular ◽  
Ventricular Assist Devices ◽  
Left Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Assist Devices ◽  
Left Ventricular Assist ◽  
End Stage Heart Failure ◽  
End Stage

Innovations in Ventricular Assist Devices for End-Stage Heart Failure

2019 ◽  
Vol 70 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Robert J.H. Miller ◽  
Jeffrey J. Teuteberg ◽  
Sharon A. Hunt
Keyword(s):  
Heart Failure ◽  
Patient Management ◽  
Left Ventricular ◽  
Ventricular Assist Devices ◽  
Left Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Assist Devices ◽  
Number Of Patients ◽  
End Stage Heart Failure ◽  
End Stage

The number of patients with end-stage heart failure (HF) continues to increase over time, but there has been little change in the availability of organs for cardiac transplantation, intensifying the demand for left ventricular assist devices (LVADs) as a bridge to transplantation. There is also a growing number of patients with end-stage HF who are not transplant candidates but may be eligible for long-term support with an LVAD, known as destination therapy. Due to this increasing demand, LVAD technology has evolved, resulting in transformative improvements in outcomes. Additionally, with growing clinical experience patient management continues to be refined, leading to iterative improvements in outcomes. With outcomes continuing to improve, the potential benefit from LVAD therapy is being considered for patients earlier in their course of advanced HF. We review recent changes in technology, patient management, and implant decision making in LVAD therapy.

Rise of the Machines: In an Era of Ventricular Assist Devices, Prolonging Life or Death?

2017 ◽  
Vol 10 (2) ◽  
pp. 96-107
Author(s):  
Oliver Diaz
Keyword(s):  
Heart Failure ◽  
Lung Function ◽  
Venous Blood ◽  
Alternative Therapy ◽  
Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Assist Devices ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Organ Replacement

The past few decades witnessed the unprecedented “rise of the machines”; life-prolonging devices to support failing organs or as a form of organ replacement. Sophisticated machines provide us clinical milieu to intervene on sicker, dying patients, support the failing organ, prevent downward trajectory to multi-organ failure, and avert death. Hemodialysis has been in existence for several decades and has become the standard therapy for acute renal failure. Extracorporeal liver assist device replaces the detoxification function of the failing liver. Extracorporeal membrane oxygenator in cases of profound respiratory failure can replace the native lung function in the oxygenation of the venous blood and removal of carbon dioxide. The technology can also be used as a short-term heart–lung machine to keep the patient alive in the event of profound refractory cardiopulmonary collapse until the native heart and lung function returns. Ventricular assist devices (VADs) can completely replace the cardiac function in patients with end-stage heart failure and provide systemic flow. These innovative machines were developed under the assumption that they will improve survival, functional capacity, and quality of life in this cohort of patients. This case study focuses on the appropriate use of VADs as an alternative therapy for end-stage heart failure. This will explicate the ethical dilemma that concomitantly may arise with the use of these sophisticated organ replacement strategies when the goals of their placement are not met and just merely prolonging the dying process.

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