Analysis of Neural Crest Cell Fate During Cardiovascular Development Using Cre-Activated lacZ/β-Galactosidase Staining

Author(s):  
Yanping Zhang ◽  
L. Bruno Ruest
2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Christopher J. Hindley ◽  
Alexandra Larisa Condurat ◽  
Vishal Menon ◽  
Ria Thomas ◽  
Luis M. Azmitia ◽  
...  

Cell Reports ◽  
2019 ◽  
Vol 29 (3) ◽  
pp. 603-616.e5
Author(s):  
Hiroyuki N. Arai ◽  
Fuminori Sato ◽  
Takuya Yamamoto ◽  
Knut Woltjen ◽  
Hiroshi Kiyonari ◽  
...  

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Walid D. Fakhouri ◽  
Jessica Wildgrube Bertol ◽  
Victoria K. Xie ◽  
Shelby Johnston ◽  
Kelsea Hubka ◽  
...  

2019 ◽  
Author(s):  
Maneeshi S. Prasad ◽  
Eileen Uribe-Querol ◽  
Jonathan Marquez ◽  
Stephanie Vadasz ◽  
Nathan Yardley ◽  
...  

AbstractCell fate specification defines the earliest steps towards a distinct cell lineage. Neural crest, a multipotent stem cell population, is thought to be specified from the ectoderm, but its varied contributions defy canons of segregation potential and challenges its embryonic origin. Aiming to resolve this conflict, we have assayed the earliest specification of neural crest using blastula stage chick embryos. Specification assays on isolated chick epiblast explants identify an intermediate region specified towards the neural crest cell fate. Furthermore, low density culture suggests that the specification of intermediate cells towards the neural crest lineage is independent of contact mediated induction. Finally, we have validated the regional identity of the intermediate region towards the neural crest cell fate using fate map studies in blastula stage chick embryos. Our results suggest a model of neural crest specification at blastula stage, with restricted ectoderm and mesoderm capacities.


2007 ◽  
Vol 1 (4) ◽  
pp. 199-201 ◽  
Author(s):  
Frances Lefcort ◽  
Lynn George

2010 ◽  
Vol 12 (6) ◽  
pp. 709-713 ◽  
Author(s):  
Ganesh M. Shankar ◽  
Li Chen ◽  
Albert H. Kim ◽  
Gina L. Ross ◽  
Rebecca D. Folkerth ◽  
...  

Extraadrenal paragangliomas are most commonly found in the carotid body and are also found with lower frequency in the CNS. These lesions are derived from the sympathoadrenal lineage of neural crest cells. Here, the authors report a rare case of a composite paraganglioma with ganglioneuromatous components found at the filum terminale in a patient who presented with a brief history of low-back pain and paresthesias in the inguinal region. Immunohistochemical analysis of the resected lesion revealed admixed elements of neuroendocrine and neuroblastoma lineages, indicating the presence of divergent differentiation of sympathoadrenal progenitor cells. This case represents a unique opportunity to understand the cell fate of sympathoadrenal progenitor cells. Here, the authors propose that paragangliomas at the filum terminale can revert to a neural crest cell precursor fate, giving rise to divergent neoplastic populations.


2011 ◽  
Vol 356 (1) ◽  
pp. 197-198
Author(s):  
Yanping Zhang ◽  
Mitchell T. McKnight ◽  
L. Bruno Ruest

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