Role of Sodium Fluoride-PET in Primary Bone Tumors

Author(s):  
Vivek Subbiah ◽  
Kalevi Kairemo
2016 ◽  
Vol 4 (10) ◽  
Author(s):  
Julio Brandao Guimaraes ◽  
Luca Facchetti ◽  
Leticia Rigo ◽  
Diego Lessa Garcia ◽  
Pricila Gama ◽  
...  

2020 ◽  
pp. 47-48
Author(s):  
Namrita Sachdev ◽  
Yashvant Singh ◽  
Kavita Vani ◽  
Rushil Jain ◽  
Dinesh Sethi

Background Radiographs are the most valuable modality for diagnosis of bone tumors, however MRI is emerging as the modality of choice for assessing local spread of tumor. Objective To assess role of MRI in local spread of tumor and comparison to surgical & histo-pathological results. Results 47 patients ( age 10-73 years with mean age of 38 years) were studied from May 2018 to November 2019. There were 26 males and 21 females, 9 patients were excluded as no operative results were available. Out of the 38 total cases, 11 were osteosarcoma, 7 were Ewing’s sarcoma, 7 were GCT, 6 were Chondrosarcoma, 2 Osteochondroma, 1 PNET, 1 ABC, 1 Hemangioma, 1 Chordoma and 1 Multiple myeloma. Cortical break was detected in 29 patients on MRI with 2 false positive cases showing 93% accuracy. Medulla involvement was detected in 34/35 patients (97%). Neuro-vascular involvement was detected in 9 patients on MRI with 1 false positive cases showing 88.9% accuracy. Joint involvement was detected in 13 patients on MRI with 2 false positive cases showing 84.6% accuracy. All 4 cases of skip lesion (100%) were detected on MRI. Conclusion MRI is the modality of choice to assess for local spread of bone tumors.


1982 ◽  
Vol 21 (04) ◽  
pp. 136-139 ◽  
Author(s):  
C.-J. Edeling

Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the primary tumor in 43 cases, skeletal metastases in 6 cases and soft-tissue metastases in 8 cases. In 25 patients with secondary malignant bone tumors, bone scintigraphy visualized a single lesion in 10 cases and several lesions in 15 cases, and 67Ga scintigraphy detected the primary tumor in 17 cases, skeletal metastases in 17 cases and soft-tissue metastases in 9 cases. In 21 patients with benign bone disease positive uptake of 99mTc-phosphonate was recognized in 19 cases and uptake of 67Ga in 17 cases. It is concluded that bone scintigraphy should be used in patients suspected of primary bone tumors. If malignancy is suspected, 67Ga scintigraphy should be performed in addition.


2019 ◽  
Vol 65 (2) ◽  
pp. 165-171
Author(s):  
Aleksey Belyaev ◽  
Georgiy Prokhorov ◽  
Anna Arkhitskaya

A review of the literature shows that surgical procedures will remain the standard treatment for primary bone tumors. Analysis of studies on the assessment of long-term results shows that additional double cryogenic treatment of the curettage cavity can improve the treatment outcomes of patients with giant cell tumors, dysplastic diseases and some forms of malignant lesions. The traditional execution of the procedure is associated with the open installation of liquid nitrogen in the bone cavity, which requires special skills in handling aggressive refrigerant from the staff and does not exclude complications. In case of multiple metastatic bone lesions, surgical treatment is not indicated. The recent emergence in clinical practice of new equipment with a closed liquid nitrogen circulation circuit inside cryoprobes resumes interest in cryoabla-tion of bone tumor lesions using modern minimally invasive puncture cryotechnology and expanding indications for its use in patients with severe comorbidities.


Author(s):  
Alessandro Luzzati ◽  
Gennaro Maria Scotto ◽  
Luca Cannavò ◽  
Giuseppe Orlando ◽  
Alessandra Scotto di Uccio ◽  
...  

2015 ◽  
Vol 139 (9) ◽  
pp. 1149-1155 ◽  
Author(s):  
Xiaohui Niu ◽  
Hairong Xu ◽  
Carrie Y. Inwards ◽  
Yuan Li ◽  
Yi Ding ◽  
...  

Context Although primary bone tumors are extremely rare, the literature suggests that there are variations in the epidemiologic characteristics in different populations. The most frequently cited epidemiologic characteristics of primary bone tumors are derived from a large US series (Mayo Clinic), with no comparable study thus far performed in China. Objective To identify any potential epidemiologic differences between Chinese patients and a US series of patients. Design We performed a comparison study between 9200 patients treated at Beijing Ji Shui Tan Hospital (JST) and 10 165 patients treated at Mayo Clinic (MC), Rochester Minnesota. Detailed epidemiologic features were analyzed. Results We found that giant cell tumor and osteosarcoma have significantly higher incidences in the JST than the MC patients (P < .001). However, JST patients had a significantly lower incidence of Ewing sarcoma, chordoma, fibrosarcoma, myeloma, and malignant lymphoma (P < .001). For most benign and malignant bone tumors, the Chinese cohort had a more distinct male predominance than the US cohort. Malignant bone tumors had a monomodal age distribution in the JST patient group, with a bimodal age distribution in the MC cohort. Also, there were was a predilection for tumors of the femur and tibia among the JST patients (P < .001). Conclusions Our data confirm that epidemiologic variations of primary bone tumors exist in different populations. Factors that may contribute to these observed differences are proposed and discussed.


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