Hypoglycaemic Agents

2021 ◽  
pp. 811-811
Keyword(s):  
Hypoglycaemic Agents

Insulin Initiation and Concomitant OHA (Oral Hypoglycaemic Agents) in Treatment of Diabetes Mellitus—Results of the Indian Human Insulin Registry (INHIRIT)

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2293-PUB ◽  
Author(s):  
VEERANNA KARADI ◽  
DILIP PAWAR ◽  
SARAH JABEEN ◽  
SANDEEP S. ◽  
SAPTARSHI BOSE ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Human Insulin ◽  
Insulin Initiation ◽  
Oral Hypoglycaemic Agents ◽  
Hypoglycaemic Agents ◽  
Treatment Of Diabetes

Nano Carriers Based Approaches for Bioavailability Enhancement of Ora l Hypoglycaemic Agents

2017 ◽  
Vol 7 (3) ◽  
Author(s):  
Akhlesh K. Jain ◽  
Parasuraman Mohan ◽  
Sunil K. Jain ◽  
Karthikeyan Kesavan
Keyword(s):  
Bioavailability Enhancement ◽  
Hypoglycaemic Agents

Hypoglycaemic agents*: variants of tolbutamide

1964 ◽  
Vol 16 (10) ◽  
pp. 677-689 ◽  
Author(s):  
D. F. HAYMAN ◽  
G. B. JACKMAN ◽  
V. PETROW ◽  
O. STEPHENSON ◽  
A. M. WILD
Keyword(s):  
Hypoglycaemic Agents

scholarly journals Design and Synthesis of Pyrazole-3-one Derivatives as Hypoglycaemic Agents

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Prasanna A. Datar ◽  
Sonali R. Jadhav
Keyword(s):  
Amino Acid ◽  
Docking Studies ◽  
Diabetic Rats ◽  
Hypoglycemic Activity ◽  
Amino Acid Residues ◽  
Docking Score ◽  
Design And Synthesis ◽  
Hypoglycaemic Agents ◽  
Standard Compound

Pyrazole-3-one compounds were designed on the basis of docking studies of previously reported antidiabetic pyrazole compounds. The amino acid residues found during docking studies were used as guidelines for the modification of aromatic substitutions on pyrazole-3-one structure. Depending on the docking score, the designed compounds were selectively prioritized for synthesis. The synthesized compounds were subjected to in vivo hypoglycemic activity using alloxan induced diabetic rats and metformin as a standard. Compound 4 having sulphonamide derivative was found to be the most potent compound among the series.

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