2000 ◽  
Vol 355 (1401) ◽  
pp. 1187-1190 ◽  
Author(s):  
Craig W. Hawryshyn

Polarization vision in vertebrates has been marked with significant controversy over recent decades. In the last decade, however, models from two laboratories have indicated that the spatial arrangement of photoreceptors provides the basis for polarization sensitivity.Work in my laboratory, in collaboration with I. Novales Flamarique and F. I. Harosi, has shown that polarization sensitivity depends on a well–defined square cone mosaic pattern and that the biophysical properties of the square cone mosaic probably account for polarization vision in the ultraviolet spectrum. The biophysical mechanism appears to be based on the selective reflection of axial–polarized light by the partitioning membrane, formed along the contact zone between the members of the double cones, onto neighbouring ultraviolet–sensitive cones. In this short review, I discuss the historical development of this research problem.


2010 ◽  
Vol 8 (17) ◽  
pp. 9-9
Author(s):  
O. Masuda ◽  
H. Hofer ◽  
J. Carroll ◽  
D. R. Williams

2008 ◽  
Vol 25 (3) ◽  
pp. 283-287
Author(s):  
CHRISTINA PETTAN-BREWER ◽  
LI FU ◽  
SAMIR S. DEEB

Many attempts have been made over the years to distinguish human and primate L (long-wavelength sensitive) from M (middle-wavelength sensitive) cone photoreceptors using either immunohistochemistry or in situ hybridization. These attempts have been unsuccessful due to the very high degree of identity between the sequences of the L and M proteins and encoding mRNAs. The recent development of chemically modified oligonucleotide probes, referred to as locked nucleic acid (LNA) probes, has shown that they hybridize with much greater affinity and specificity to the target nucleic acid. This has greatly increased the potential for differentiating L from M cones by in situ hybridization. We have designed LNA oligonucleotide probes that are complementary to either the L or M coding sequences located in exon 5 of the Macaca nemestrina L and M pigment genes. We have shown that the LNA-M and LNA-L probes hybridize specifically to their respective target nucleic acid sequences in vitro. This result strongly suggests that these probes would be instrumental in rapidly distinguishing L from M cone in the entire retina, and in defining the cone mosaic during development and in adults.


Author(s):  
Francesco LaRocca ◽  
Derek Nankivil ◽  
Theodore B. DuBose ◽  
Cynthia A. Toth ◽  
Sina Farsiu ◽  
...  
Keyword(s):  

2014 ◽  
Vol 56 (1) ◽  
pp. 352-364 ◽  
Author(s):  
Y. Ji ◽  
W.-Q. Yu ◽  
Y. S. Eom ◽  
F. Bruce ◽  
C. M. Craft ◽  
...  

2017 ◽  
Vol 34 ◽  
Author(s):  
ALISON L. HUCKENPAHLER ◽  
MELISSA A. WILK ◽  
ROBERT F. COOPER ◽  
FRANCIE MOEHRING ◽  
BRIAN A. LINK ◽  
...  

2020 ◽  
Vol 55 (3) ◽  
pp. 232-238
Author(s):  
Rebika Dhiman ◽  
Vinay Gupta ◽  
Rohan Chawla ◽  
Atul Kumar ◽  
Rohit Saxena

2017 ◽  
Vol 58 (9) ◽  
pp. 3395 ◽  
Author(s):  
Lucie Sawides ◽  
Kaitlyn A. Sapoznik ◽  
Alberto de Castro ◽  
Brittany R. Walker ◽  
Thomas J. Gast ◽  
...  

2010 ◽  
Vol 18 (24) ◽  
pp. 24902 ◽  
Author(s):  
Nicole M. Putnam ◽  
Daniel X. Hammer ◽  
Yuhua Zhang ◽  
David Merino ◽  
Austin Roorda

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