Biophysical and Gastro-Intestinal Engineering Aspects of Nutrient Absorption and Physiological Function

Author(s):  
Mike Boland
Author(s):  
John C. Garancis ◽  
R. A. Pattillo

Growth of cell system (BeWo-cell line) derived from human gestational choriocarcinoma has been established and continuously maintained in-vitro. Furthermore, it is evident from the previous studies that this cell line has retained the physiological function of the placental trophoblasts, namely the synthesis of human chorionic gonadotrophil(HCG).The BeWo cells were relatively small and possessed single nuclei, thus indicating that this cell line consists exclusively of cytotrophoblasts. In some instances cells appeared widely separated and their lateral surfaces were provided with numerous microvilli (Fig.1).


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