TVnet: Automated Time-Resolved Tracking of the Tricuspid Valve Plane in MRI Long-Axis Cine Images with a Dual-Stage Deep Learning Pipeline

2021 ◽  
pp. 567-576
Author(s):  
Ricardo A. Gonzales ◽  
Jérôme Lamy ◽  
Felicia Seemann ◽  
Einar Heiberg ◽  
John A. Onofrey ◽  
...  
Author(s):  
Guoqiang Wang ◽  
Garry Wei-Han Tan ◽  
Yunpeng Yuan ◽  
Keng-Boon Ooi ◽  
Yogesh K. Dwivedi

2019 ◽  
Vol 875 ◽  
Author(s):  
Jianqing Huang ◽  
Hecong Liu ◽  
Weiwei Cai

Online in situ prediction of 3-D flame evolution has been long desired and is considered to be the Holy Grail for the combustion community. Recent advances in computational power have facilitated the development of computational fluid dynamics (CFD), which can be used to predict flame behaviours. However, the most advanced CFD techniques are still incapable of realizing online in situ prediction of practical flames due to the enormous computational costs involved. In this work, we aim to combine the state-of-the-art experimental technique (that is, time-resolved volumetric tomography) with deep learning algorithms for rapid prediction of 3-D flame evolution. Proof-of-concept experiments conducted suggest that the evolution of both a laminar diffusion flame and a typical non-premixed turbulent swirl-stabilized flame can be predicted faithfully in a time scale on the order of milliseconds, which can be further reduced by simply using a few more GPUs. We believe this is the first time that online in situ prediction of 3-D flame evolution has become feasible, and we expect this method to be extremely useful, as for most application scenarios the online in situ prediction of even the large-scale flame features are already useful for an effective flame control.


2020 ◽  
Vol 157 ◽  
pp. 113477 ◽  
Author(s):  
Voon-Hsien Lee ◽  
Jun-Jie Hew ◽  
Lai-Ying Leong ◽  
Garry Wei-Han Tan ◽  
Keng-Boon Ooi
Keyword(s):  

2020 ◽  
Author(s):  
Somesh Mohapatra ◽  
Nina Hartrampf ◽  
Mackenzie Poskus ◽  
Andrei Loas ◽  
Rafael Gomez-Bombarelli ◽  
...  

<p>Chemical synthesis of polypeptides involves stepwise formation of amide bonds on an immobilized solid support. The high yields required for efficient incorporation of each individual amino acid in the growing chain are often impacted by sequence-dependent events such as aggregation. Here we apply deep learning over ultraviolet-visible (UV-Vis) analytical data collected from 35,485 individual fluorenylmethyloxycarbonyl (Fmoc) deprotection reactions performed with an automated fast-flow peptide synthesizer. The integral, height and width of these time-resolved UV-Vis deprotection traces indirectly allow for analysis of the iterative amide coupling cycles on resin. The computational model maps structural representations of amino acids and peptide sequences to experimental synthesis parameters and predicts the outcome of deprotection reactions with less than 4% error. Our deep learning approach enables experimentally-aware computational design for prediction of Fmoc deprotection efficiency and minimization of aggregation events, building the foundation for real-time optimization of peptide synthesis in flow.</p>


2021 ◽  
Vol 27 (S1) ◽  
pp. 464-465
Author(s):  
Ramon Manzorro ◽  
Matan Leibovich ◽  
Joshua Vincent ◽  
Sreyas Mohan ◽  
David Matteson ◽  
...  

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