Dual serotonin and noradrenaline uptake inhibitor class of antidepressants — Potential for greater efficacy or just hype?

Progress in Drug Research ◽

10.1007/978-3-0348-8183-8_5 ◽

2002 ◽

pp. 169-222 ◽

Author(s):

David T. Wong ◽

Frank P. Bymaster

Keyword(s):

Noradrenaline Uptake ◽

Uptake Inhibitor

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Analgesic effects of a new serotonin/noradrenaline uptake inhibitor (Ro 15-8081) in comparison with codeine and placebo on experimentally induced pain in healthy men

Pain ◽

10.1016/0304-3959(87)91900-2 ◽

1987 ◽

Vol 30 ◽

pp. S422

Author(s):

G. Stacher ◽

S. Schneider ◽

G. Gaupmann ◽

Th. Abatzi ◽

G. Stacher-Janotta ◽

...

Keyword(s):

Noradrenaline Uptake ◽

Uptake Inhibitor ◽

Healthy Men ◽

Analgesic Effects ◽

Experimentally Induced

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A double?blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression

Acta Psychiatrica Scandinavica ◽

10.1111/j.1600-0447.1982.tb00914.x ◽

1982 ◽

Vol 66 (1) ◽

pp. 50-65 ◽

Author(s):

A. Åberg-Wistedt

Keyword(s):

Endogenous Depression ◽

Blind Study ◽

Serotonin Uptake ◽

Double Blind Study ◽

Noradrenaline Uptake ◽

Double Blind ◽

Uptake Inhibitor ◽

Serotonin Uptake Inhibitor

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Effect of a Serotonin and Noradrenaline Uptake Inhibitor in Panic Disorder; a Double-blind Comparative Study with Fluvoxamine and Maprotiline

International Clinical Psychopharmacology ◽

10.1097/00004850-198801000-00005 ◽

1988 ◽

Vol 3 (1) ◽

pp. 59-74 ◽

Author(s):

JOHAN A. DEN BOER ◽

HERMAN G. M. WESTENBERG

Keyword(s):

Panic Disorder ◽

Comparative Study ◽

Noradrenaline Uptake ◽

Double Blind ◽

Uptake Inhibitor

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Effects of graded oral doses of a new 5-hydroxytryptamine/noradrenaline uptake inhibitor (Ro 15-8081) in comparison with 60 mg codeine and placebo on experimentally induced pain and side effect profile in healthy men.

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.1987.tb03222.x ◽

1987 ◽

Vol 24 (5) ◽

pp. 627-635 ◽

Author(s):

G Stacher ◽

H Steinringer ◽

S Schneider ◽

G Mittelbach ◽

G Gaupmann ◽

...

Keyword(s):

Side Effect ◽

Side Effect Profile ◽

Noradrenaline Uptake ◽

Uptake Inhibitor ◽

Healthy Men ◽

Experimentally Induced

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Neonatal treatments with the serotonin uptake inhibitors clomipramine and zimelidine, but not the noradrenaline uptake inhibitor desipramine, disrupt sleep patterns in adult rats

Brain Research ◽

10.1016/s0006-8993(97)00657-4 ◽

1997 ◽

Vol 768 (1-2) ◽

pp. 287-293 ◽

Author(s):

Marcos Gabriel Frank ◽

Horace Craig Heller

Keyword(s):

Serotonin Uptake ◽

Noradrenaline Uptake ◽

Sleep Patterns ◽

Serotonin Uptake Inhibitors ◽

Uptake Inhibitor ◽

Uptake Inhibitors

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Oxaprotiline, a noradrenaline uptake inhibitor with an active and an inactive enantiomer

Biochemical Pharmacology ◽

10.1016/0006-2952(82)90510-x ◽

1982 ◽

Vol 31 (12) ◽

pp. 2169-2176 ◽

Author(s):

P.C. Waldmeier ◽

P.A. Baumann ◽

K. Hauser ◽

L. Maitre ◽

A. Storni

Keyword(s):

Noradrenaline Uptake ◽

Uptake Inhibitor

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A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression

Acta Psychiatrica Scandinavica ◽

10.1111/j.1600-0447.1982.tb00915.x ◽

1982 ◽

Vol 66 (1) ◽

pp. 66-82 ◽

Author(s):

A. Åberg-Wistedt ◽

S. B. Ross ◽

K.-G. Jostell ◽

B. Sjöquist

Keyword(s):

Endogenous Depression ◽

Blind Study ◽

Serotonin Uptake ◽

Double Blind Study ◽

Noradrenaline Uptake ◽

Double Blind ◽

Uptake Inhibitor ◽

Serotonin Uptake Inhibitor

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The noradrenaline uptake inhibitor, (+)-oxaprotiline, but not the inactive enantiomer, (−)-oxaprotiline, inhibits sympathetic nerve activity in the rabbit: involvement of adrenoceptors

European Journal of Pharmacology ◽

10.1016/0014-2999(91)90496-d ◽

1991 ◽

Vol 199 (3) ◽

pp. 325-334 ◽

Author(s):

Bela Szabo ◽

Andrea Schultheiss ◽

Klaus Starke

Keyword(s):

Sympathetic Nerve ◽

Sympathetic Nerve Activity ◽

Noradrenaline Uptake ◽

Nerve Activity ◽

Uptake Inhibitor

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Exploring the molecular structure, vibrational spectroscopic, quantum chemical calculation and molecular docking studies of curcumin: A potential PI3K/AKT uptake inhibitor

Heliyon ◽

10.1016/j.heliyon.2021.e06646 ◽

2021 ◽

Vol 7 (4) ◽

pp. e06646

Author(s):

M. Govindammal ◽

M. Prasath ◽

S. Kamaraj ◽

S. Muthu ◽

M. Selvapandiyan

Keyword(s):

Molecular Structure ◽

Molecular Docking ◽

Quantum Chemical Calculation ◽

Quantum Chemical ◽

Docking Studies ◽

Chemical Calculation ◽

Uptake Inhibitor ◽

Molecular Docking Studies

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Anticonvulsant activity of the glial GABA uptake inhibitor, THAO, in chemical seizures

European Journal of Pharmacology ◽

10.1016/0014-2999(89)90576-1 ◽

1989 ◽

Vol 168 (2) ◽

pp. 265-268 ◽

Author(s):

Susan F. Gonsalves ◽

Bonnie Twitchell ◽

Robert E. Harbaugh ◽

Povl Krogsgaard-Larsen ◽

Arne Schousboe

Keyword(s):

Anticonvulsant Activity ◽

Gaba Uptake ◽

Uptake Inhibitor ◽

Gaba Uptake Inhibitor

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