Discriminating Graph Pattern Mining from Gene Expression Data

Author(s):  
Fabio Fassetti ◽  
Simona E. Rombo ◽  
Cristina Serrao
2016 ◽  
Vol 16 (3) ◽  
pp. 26-36
Author(s):  
Fabio Fassetti ◽  
Simona E. Rombo ◽  
Cristina Serrao

BMC Genomics ◽  
2011 ◽  
Vol 12 (Suppl 3) ◽  
pp. S5 ◽  
Author(s):  
Mingoo Kim ◽  
Hyunjung Shin ◽  
Tae Su Chung ◽  
Je-Gun Joung ◽  
Ju Han Kim

2012 ◽  
Vol 4 ◽  
pp. 807-811 ◽  
Author(s):  
Shruti Mishra ◽  
Sandeep Ku. Satapathy ◽  
Debahuti Mishra

Author(s):  
Bruno Crémilleux ◽  
Arnaud Soulet ◽  
Jiri Kléma ◽  
Céline Hébert ◽  
Olivier Gandrillon

The discovery of biologically interpretable knowledge from gene expression data is a crucial issue. Current gene data analysis is often based on global approaches such as clustering. An alternative way is to utilize local pattern mining techniques for global modeling and knowledge discovery. Nevertheless, moving from local patterns to models and knowledge is still a challenge due to the overwhelming number of local patterns and their summarization remains an open issue. This chapter is an attempt to fulfill this need: thanks to recent progress in constraint-based paradigm, it proposes three data mining methods to deal with the use of local patterns by highlighting the most promising ones or summarizing them. Ideas at the core of these processes are removing redundancy, integrating background knowledge, and recursive mining. This approach is effective and useful in large and real-world data: from the case study of the SAGE gene expression data, we demonstrate that it allows generating new biological hypotheses with clinical application.


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