Nowadays, wireless network technology in smart home is rapid gaining popularity duo to its flexible integration into everyday life. The paper introduces a method that adopts 433MHZ communication to establish the wireless network in smart home system based on Si4421 wireless modules. The paper designed the overall idea of how to establish the wireless network, it mainly talk about the wireless module, including both software and hardware. The difficulty lies in the realization of the custom wireless communication protocol. The Si4421 wireless module was tested in data communication and control in smart home system which can work efficiently and reliably, it proved that the wireless module is perfectly suitable for the wireless network construction in smart home with small size package, low consumption, low cost, and strong ability to leap obstacles.