Learning Bayesian Networks by Lamarckian Genetic Algorithm and Its Application to Yeast Cell-Cycle Gene Network Reconstruction from Time-Series Microarray Data

Author(s):  
Sun-Chong Wang ◽  
Sai-Ping Li
2015 ◽  
Vol 42 (10) ◽  
pp. 1485-1485
Author(s):  
Xun Xia ◽  
Bo Qu ◽  
Yuan Ma ◽  
Li-bin Yang ◽  
Hai-dong Huang ◽  
...  

Author(s):  
Ramesh Ram ◽  
Madhu Chetty

This chapter presents modelling gene regulatory networks (GRNs) using probabilistic causal model and the guided genetic algorithm. The problem of modelling is explained from both a biological and computational perspective. Further, a comprehensive methodology for developing a GRN model is presented where the application of computation intelligence (CI) techniques can be seen to be significantly important in each phase of modelling. An illustrative example of the causal model for GRN modelling is also included and applied to model the yeast cell cycle dataset. The results obtained are compared for providing biological relevance to the findings which thereby underpins the CI based modelling techniques.


2020 ◽  
Vol 116 ◽  
pp. 103577 ◽  
Author(s):  
Konstantina Kourou ◽  
George Rigas ◽  
Costas Papaloukas ◽  
Michalis Mitsis ◽  
Dimitrios I. Fotiadis

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