scholarly journals UDP‐Glucuronyl Transferase

1967 ◽  
Vol 1 (3) ◽  
pp. 221-222 ◽  
Author(s):  
Elias Halac ◽  
Pamela Weiss ◽  
Joseph Dancis

1973 ◽  
Vol 82 (1) ◽  
pp. 118-120
Author(s):  
Keti Malaka-Zafiriu ◽  
I. Tsiouris ◽  
C. Cassimos

PEDIATRICS ◽  
1971 ◽  
Vol 47 (5) ◽  
pp. 811-817
Author(s):  
Gerhard Levy ◽  
Inta J. Ertel

The formation of glucuronides of salicylate, salicylamide, and acetaminophen in two sisters with congenital unconjugated hyperbilirubinemia responsive to phenobarbital was normal at widely different (6 to 37 mg per 100 ml) serum bilirubin concentrations. The conjugation of salicylate with glycine, and the formation of salicylamide sulfate and acetaminophen sulfate were also normal. This shows that unconjugated hyperbilirubinemia per se does not affect the biotransformation of the three drugs tested. The clinical and pharmacokinetic characteristics of the children in this study are consistent with a recently proposed mechanism involving a deficiency in hepatic anion-binding protein (rather than glucuronyl transferase) as one cause of unconjugated hyperbilirubinemia.


1990 ◽  
Vol 39 (6) ◽  
pp. 1085-1093 ◽  
Author(s):  
Catherine M. Neumann ◽  
Vincent G. Zannoni

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