scholarly journals Femtosecond laser fabrication for the integration of optical sensors in microfluidic lab-on-chip devices

Author(s):  
R. Osellame ◽  
R. Martinez Vazquez ◽  
C. Dongre ◽  
R. Dekker ◽  
H. J. W. M. Hoekstra ◽  
...  
2004 ◽  
Vol 78 (7) ◽  
pp. 1029-1032 ◽  
Author(s):  
M. Masuda ◽  
K. Sugioka ◽  
Y. Cheng ◽  
T. Hongo ◽  
K. Shihoyama ◽  
...  

2013 ◽  
Vol 448-453 ◽  
pp. 396-401
Author(s):  
Nuno Miguel Matos Pires ◽  
Tao Dong

Routine analysis of steroid hormones in environmental water samples demands for cost-effective tools that can detect multiple targets simultaneously. This study reports a high-throughput polymer platform integrated to polymer optical sensors for on-site monitoring of hormones in water. This opto-microfluidic device concept is fully compatible to low-cost fabrication methods. A competitive chemiluminescence immunoassay was performed onto gold thin film coated chambers, and a detection resolution of roughly 0.2 ng/mL was obtained using 17β-estradiol as the model target. Furthermore, the integrated polymer platform showed good recovery for the estradiol target when spiked in surface water samples.


2003 ◽  
Author(s):  
Ya Cheng ◽  
Koji Sugioka ◽  
Masashi Masuda ◽  
Katsumi Midorikawa ◽  
Masako Kawachi ◽  
...  

Author(s):  
R. Osellame ◽  
R. Martinez Vazquez ◽  
R. Ramponi ◽  
G. Cerullo ◽  
C. Dongre ◽  
...  

2004 ◽  
Vol 79 (4-6) ◽  
pp. 815-817 ◽  
Author(s):  
K. Sugioka ◽  
M. Masuda ◽  
T. Hongo ◽  
Y. Cheng ◽  
K. Shihoyama ◽  
...  

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 547
Author(s):  
Fengping Li ◽  
Guang Feng ◽  
Xiaojun Yang ◽  
Chengji Lu ◽  
Guang Ma ◽  
...  

A quickly tunable wettability pattern plays an important role in regulating the surface behavior of liquids. Light irradiation can effectively control the pattern to achieve a specific wettability pattern on the photoresponsive material. However, metal oxide materials based on light adjustable wettability have a low regulation efficiency. In this paper, zinc (Zn) superhydrophobic surfaces can be obtained by femtosecond-laser-ablated microholes. Owing to ultraviolet (UV) irradiation increasing the surface energy of Zn and heating water temperature decreasing the surface energy of water, the wettability of Zn can be quickly tuned photothermally. Then, the Zn superhydrophobic surfaces can be restored by heating in the dark. Moreover, by tuning the pattern of UV irradiation, a specific wettability pattern can be transferred by the Zn microholes, which has a potential application value in the field of new location-controlled micro-/nanofluidic devices, such as microreactors and lab-on-chip devices.


Micromachines ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1421
Author(s):  
Zong-Da Zhang ◽  
Yan-Zhao Duan ◽  
Qi Guo ◽  
Si Gao ◽  
Bing-Rong Gao

Recently, optical sensors interacting with evanescent fields and the external environment around waveguides have attracted extensive attention. In the process of light propagation in the waveguide, the depth of the evanescent field is closely related to the accuracy of the optical sensor, and adjusting the depth of the evanescent field to obtain higher accuracy has become the primary challenge in fabricating on-chip optical sensors. In this study, the waveguide structure of a Mach–Zehnder interferometer was written directly in Corning Eagle 2000 borosilicate glass by a femtosecond laser, and the sensing window was exposed out of the bulk material by mechanical polishing. The refractive index detection device based on the proposed on-chip Mach–Zehnder interferometer has the advantages of small volume, light weight, and good stability. Its sensitivity can reach 206 nm/RIU or 337 dB/RIU, and the theoretical maximum measurement range is 1–1.508. Therefore, it can measure the refractive index quickly and accurately in extreme or complex environments, and has excellent application prospects.


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