Effect of Corrosion and Biofilm on Friction Behavior in Biotribocorrosion System for Metal-on-Metal Hip Prosthesis

2009 ◽  
pp. 829-830
Author(s):  
Yu Yan ◽  
Duncan Dowson ◽  
Sophie Williams ◽  
Anne Neville ◽  
John Fisher
Keyword(s):  
Hip Prosthesis ◽  
Friction Behavior ◽  
Metal On Metal

scholarly journals Chromium and cobalt intoxication mimicking mitochondriopathy

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Tim W. Rattay ◽  
Torsten Kluba ◽  
Ludger Schöls
Keyword(s):  
Diabetes Mellitus ◽  
Weight Loss ◽  
Mitochondrial Dna ◽  
Wear Debris ◽  
Hip Prosthesis ◽  
Mitochondrial Cytopathy ◽  
Whole Exome ◽  
Metal On Metal ◽  
Metal Wear ◽  
History Of

AbstractA 53-year old male with a history of progressive visual impairment, hearing loss, peripheral neuropathy, poorly controlled diabetes mellitus, cardiomyopathy, and weight loss was referred to the rare disease center due to the suspicion of mitochondrial cytopathy. In line with mitochondrial dysfunction, lactate in CSF was increased. Genetic testing by whole-exome sequencing and mitochondrial DNA did not reveal a likely cause. The case remained unsolved until he developed pain in his right hip, where he had received total hip arthroplasty 12 years earlier. An orthopedic evaluation revealed substantial shrinkage of the head of the hip prosthesis. Due to metal-on-metal wear, debris chromium and cobalt levels in serum were massively increased and significantly improved with multisystemic impairment after exchanging the defective implant.

scholarly journals Metal-on-metal total hip arthroplasty: does increasing modularity affect clinical outcome?

2020 ◽  
pp. 112070002097927
Author(s):  
Kevin C Ilo ◽  
Harry S Hothi ◽  
John A Skinner ◽  
Alister J Hart
Keyword(s):  
Metal Ion ◽  
Hip Prosthesis ◽  
Tissue Reaction ◽  
Bearing Surface ◽  
Adverse Local Tissue Reaction ◽  
Material Loss ◽  
Local Tissue ◽  
Local Tissue Reaction ◽  
Metal On Metal ◽  
Modular Implants

Background: Modularity of metal-on-metal (MoM) implants has come under scrutiny due to concerns regarding additional sources of metal debris. This study is a retrieval analysis of implants from the same manufacturer with the same MoM bearing surface. The difference between the implants was presence or absence of modular junctions. Methods: This is a retrospective study of 31 retrieved implants from 31 patients who received a Conserve Wright Medical MoM hip prosthesis. The 31 implants consisted of 16 resurfacings and 15 implants with modular junctions; 4 conventional THAs and 11 modular-neck THAs. Results: 43% of pre-revision MRI scans performed on resurfacing implants and 91% performed on the modular implants illustrated evidence of an adverse local tissue reaction. There was no difference in pre-revision blood metal ion levels or bearing surface wear between the resurfacings and modular implants. The neck-head tapers of the modular group showed low levels of material loss. However, the neck-stem tapers showed increased severity of corrosion and material loss Conclusions: The modular implants had an increased incidence of adverse local tissue reaction. This could be related to the presence of modular junctions, particular the neck-stem junction which showed increased susceptibly to corrosion

A csípőprotézis-választás nehézségeinek és felelősségének bemutatása egy eset kapcsán

2021 ◽  
Vol 162 (20) ◽  
pp. 800-805
Author(s):  
Dragos Schiopu ◽  
F. Pieter Reynders ◽  
S. Tamás Illés
Keyword(s):  
Femoral Neck ◽  
Hip Joint ◽  
Hip Prosthesis ◽  
Psychiatric Symptoms ◽  
Indirect Evidence ◽  
Surface Replacement ◽  
Rapid Improvement ◽  
Metal On Metal ◽  
Depth Analysis ◽  
Tissue Reactions

Összefoglaló. A felszínpótló, fém a fémen csípőízületi protézisek reneszánszukat élték a 2000-es években. Elsősorban fiatal, aktív betegek esetében javasolták használni a remélt elméleti előnyök, mint a combfej csontállományának megőrzése, a csípőízület biomechanikájának fenntartása, a luxatio kockázatának csökkentése, a polietilén törmelékek és kopástermékek hiánya miatt. Bemutatunk egy beteget, akinél 19 éves korában kétszeri vesetranszplantációt követő, hosszan tartó szteroidkezelés következtében kialakult kétoldali combfejnekrózis miatt került sor felszínpótló, fém a fémen csípőprotézis beültetésére. A harmadik posztoperatív évtől mindkét csípőt érintő, fokozatosan súlyosbodó fájdalom, pszichés tünetek, valamint ismételt veseelégtelenség alakult ki. A tünetek hátterében kifejezetten magas Co-Cr szérumszintet, a csípőízület környezetében pszeudotumor-kialakulást, kiterjedt acetabularis cystákat, a combnyakak jelentős elvékonyodását találtuk, mely jobb oldalon periprotetikus combnyaktörést okozott. A revíziós műtétek során talált kiterjedt szöveti metallosis eltávolítását követően a felszínpótló protéziseket cement nélküli kerámia–kerámia totális protézisekre cseréltük. A revíziókat követően a lokális és pszichés tünetek megszűntek, a szérum Co-Cr szintje normalizálódott, ami lehetővé tette a harmadik vesetranszplantáció elvégzését is. Páciensünk csípőrevíziókat követő gyors javulása közvetett bizonyítékként szolgál a Co-Cr ionok negatív szerepére mind a helyi, mind a szisztémás szöveti reakciókban, így a transzplantált vese károsodásában. Esetünk tanulságai, hogy szervtranszplantációt követően kerülni kell a fém a fémen protézisek használatát, valamint hogy nem elég a csípőízületi protézis indikációjának felállítása és a legmodernebbnek tartott protézis használata. Különös gonddal és elmélyülten kell elemezni a beteg járulékos körülményeit, gyógyszerelését, társbetegségeit is ahhoz, hogy a legmegfelelőbb típusú protézist tudjuk kiválasztani, ami nem megkerülhető felelőssége az ortopéd sebészeknek. Orv Hetil. 2021; 162(20): 800–805. Summary. The surface replacement, metal on metal hip prostheses, experienced a renaissance in the 2000s. It has been recommended for use primarily in young, active patients due to expected theoretical benefits such as preserving femoral bone stock, maintaining hip joint biomechanics, reducing the risk of dislocation, and lacking polyethylene debris abrasion products. We present a patient who had resurfacing prosthesis because of bilateral femoral head necrosis due to long-term steroid treatment following double kidney transplantation at the age of 19. In the third postoperative year, progressive pain in both hips, psychiatric symptoms, and recurrent renal failure developed. We found extremely high serum Co-Cr levels, pseudotumor formation of the hip joint, extensive acetabular cysts, and significant thinning of the femoral neck, followed by a periprosthetic femoral neck fracture on one side. After removing the extensive tissue metallosis found during the revision surgeries, the surface replacement prostheses were replaced with cementless ceramic–ceramic total prostheses. Following the revisions, local and psychiatric symptoms resolved, and serum Co-Cr levels normalized, allowing a third kidney transplant to be performed. The rapid improvement of our patient after prosthesis revisions serves as indirect evidence for the negative role of Co-Cr ions in both local and systemic tissue reactions, including damage to the transplanted kidney. Our case report shows that the use of metal on metal prostheses after organ transplantation should be avoided and simply setting up an indication for hip prosthesis and use the most modern type of prosthesis is inadequate. Depth analysis of the patient’s ancillary conditions, medications, co-morbidities are required to select the most appropriate prosthesis type, which is an unavoidable responsibility of orthopedic surgeons. Orv Hetil. 2021; 162(20): 800–805.

Ion Production and Excretion in a Patient with a Metal-on-Metal Bearing Hip Prosthesis

2007 ◽  
Vol 89 (12) ◽  
pp. 2758-2763 ◽  
Author(s):  
Rudi G Bitsch ◽  
Michelle Zamorano ◽  
Travis Loidolt ◽  
Christian Heisel ◽  
Joshua J Jacobs ◽  
...  
Keyword(s):  
Hip Prosthesis ◽  
Metal On Metal ◽  
Ion Production

Surface Damage After Multiple Dislocations of a 38-mm-Diameter, Metal-on-Metal Hip Prosthesis

2008 ◽  
Vol 23 (7) ◽  
pp. 1090-1096 ◽  
Author(s):  
John G. Bowsher ◽  
Thomas K. Donaldson ◽  
Paul A. Williams ◽  
Ian C. Clarke
Keyword(s):  
Hip Prosthesis ◽  
Surface Damage ◽  
Metal On Metal

Albumin as marker for susceptibility to metal ions in metal-on-metal hip prosthesis patients

2016 ◽  
Vol 36 (4) ◽  
pp. 319-327 ◽  
Author(s):  
F Facchin ◽  
S Catalani ◽  
E Bianconi ◽  
D De Pasquale ◽  
S Stea ◽  
...  
Keyword(s):  
Health Status ◽  
Blood Serum ◽  
Whole Blood ◽  
Metal Binding ◽  
Hip Prosthesis ◽  
Binding Capacity ◽  
Gene Mutations ◽  
Individual Susceptibility ◽  
Metal On Metal ◽  
Serum And Urine

Metal-on-metal (MoM) hip prostheses are known to release chromium and cobalt (Co), which negatively affect the health status, leading to prosthesis explant. Albumin (ALB) is the main serum protein-binding divalent transition metals. Its binding capacity can be affected by gene mutations or modification of the protein N-terminal region, giving the ischaemia-modified albumin (IMA). This study evaluated ALB, at gene and protein level, as marker of individual susceptibility to Co in MoM patients, to understand whether it could be responsible for the different management of this ion. Co was measured in whole blood, serum and urine of 40 MoM patients. A mutational screening of ALB was performed to detect links between mutations and metal binding. Finally, serum concentration of total ALB and IMA were measured. Serum total ALB concentration was in the normal range for all patients. None of the subjects presented mutations in the investigated gene. Whole blood, serum and urine Co did not correlate with serum total ALB or IMA, although IMA was above the normal limit in most subjects. The individual susceptibility is very important for patients’ health status. Despite the limited results of this study, we provide indications on possible future investigations on the toxicological response to Co.

Monocyte chemoattractant protein-1 is strongly expressed during the process of wearing of metal on metal hip prosthesis

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S264
Author(s):  
M. Montesi ◽  
A. Beraudi ◽  
S. Stea ◽  
S. Falcioni ◽  
S. Squarzoni ◽  
...  
Keyword(s):  
Hip Prosthesis ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Metal On Metal
Sign in / Sign up

Export Citation Format

Share Document