Automated Cell Nuclei Segmentation in Breast Cancer Fine Needle Biopsy Smears

Author(s):  
Marek Kowal ◽  
Andrzej Obuchowicz
2015 ◽  
Vol 2 (1) ◽  
pp. 29-33
Author(s):  
O. Andronic ◽  
D. Ion ◽  
Izabela Marin ◽  
Georgiana Radu ◽  
D. N. Păduraru

Phyllodes tumor (PT) is an uncommon and distinct category of breast cancer, being a particular form of intracanalicular fibroadenoma. A definitive diagnosis is difficult to make just based on imaging investigations and fine needle biopsy; also PTs are frequently misinterpreted as breast fibroadenomas. In the case of of a 26-year old woman with a suspected PT (based on clinical investigation) which was first diagnosed as a fibroadenoma using ultrasonography and preoperative biopsy, further investigation was needed. A limited resection was performed and the postoperative histopathology confirmed the diagnosis as PT.


Author(s):  
Andrzej Marciniak ◽  
Andrzej Obuchowicz ◽  
Roman Monczak ◽  
Mariusz Kołodziński

Author(s):  
Maciej Hrebień ◽  
Piotr Steć ◽  
Tomasz Nieczkowski ◽  
Andrzej Obuchowicz

Segmentation of Breast Cancer Fine Needle Biopsy Cytological ImagesThis paper describes three cytological image segmentation methods. The analysis includes the watershed algorithm, active contouring and a cellular automata GrowCut method. One can also find here a description of image pre-processing, Hough transform based pre-segmentation and an automatic nuclei localization mechanism used in our approach. Preliminary experimental results collected on a benchmark database present the quality of the methods in the analyzed issue. The discussion of common errors and possible future problems summarizes the work and points out regions that need further research.


1994 ◽  
Vol 81 (8) ◽  
pp. 1150-1150
Author(s):  
N. J. Carty ◽  
D. Ravichandran ◽  
M. Cross ◽  
C. D. Johnson ◽  
A. Herbert ◽  
...  

1977 ◽  
Vol 25 (7) ◽  
pp. 560-564 ◽  
Author(s):  
K Goerttler ◽  
V Ehemann ◽  
C Tschahargane ◽  
M Stoehr

We collected prostatic glands from 50 unselected autopsies at the Pathology Institute and compared their histologic sections with cytologic preparations and with results of photometric measurements of isolated prostatic cells and isolated nuclei. The results obtained with single cell photometry and flow-through cytophotometry proved to be comparable with one another and with the results of the cytologic and histologic studies. With these methods of cytophotometry we could differentiate inflammatory conditions, microcarcinomas and frank carcinomas from normal and hyperplastic prostatic tissue. We had difficulties, however, preparing adequate suspensions of cell nuclei from chronic fibrosing prostatitis. Our results indicate that it should be possible for diagnostic purposes to combine the technique of fine needle biopsy of the prostate with that of flow-through cytophotometry and to use the combined techniques for studying diseases of other organs.


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