Reactive Oxygen Species Biology and Angiotensin Regulation of Human Vascular Tone – the Role of Angiotensin-Converting Enzyme (ACE) Inhibitors and AT1 Receptor Blockers (ARBs)

2014 ◽  
pp. 1273-1286
Author(s):  
Nikolaos Koumallos ◽  
Amir Sepehripour ◽  
Ioannis Dimarakis ◽  
Andreas Paschalis ◽  
Abdul Nasir ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Angiotensin Converting Enzyme ◽  
Ace Inhibitors ◽  
Vascular Tone ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Converting Enzyme ◽  
Receptor Blockers ◽  
At1 Receptor Blockers

Effects of Catechin on Activity of Angiotensin-Converting Enzyme and Generation of Reactive Oxygen Species in Rat Aorta

2020 ◽  
Vol 168 (5) ◽  
pp. 627-630
Author(s):  
V. A. Anikina ◽  
Yu. A. Kim ◽  
A. F. Korystova ◽  
M. Kh. Levitman ◽  
V. V. Shaposhnikova ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Angiotensin Converting Enzyme ◽  
Reactive Oxygen ◽  
Rat Aorta ◽  
Oxygen Species ◽  
Converting Enzyme

Reactive oxygen species: influence on cerebral vascular tone

2006 ◽  
Vol 100 (2) ◽  
pp. 739-743 ◽  
Author(s):  
Frank M. Faraci
Keyword(s):  
Reactive Oxygen Species ◽  
Vascular Tone ◽  
Reactive Oxygen ◽  
Vascular Biology ◽  
Oxygen Species ◽  
Low Concentrations ◽  
The Impact ◽  
Endothelium Dependent Relaxation ◽  
Cerebral Vascular

Reactive oxygen species have multiple effects on vascular cells. Defining the sources and the impact of the various reactive oxygen species within the vessel wall has emerged as a major area of study in vascular biology. This review will focus on recent findings related to effects of reactive oxygen species on cerebral vascular tone. Effects of superoxide radical, hydrogen peroxide, and the reactive nitrogen species peroxynitrite are summarized. Although higher concentrations may be important for cerebral vascular biology in disease, relatively low concentrations of reactive oxygen species may function as signaling molecules involved with normal regulation of cerebral vascular tone. The mechanisms by which reactive oxygen species affect vascular tone may be quite complex, and our understanding of these processes is increasing. Additionally, the role of reactive oxygen species as mediators of endothelium-dependent relaxation is addressed. Finally, the consequences of the molecular interactions of superoxide with nitric oxide and arachidonic acid are discussed.

Effects of High-Salt Diet on the Activity of Angiotensin-Converting Enzyme and Generation of Reactive Oxygen Species in Rat Aorta

2014 ◽  
Vol 156 (6) ◽  
pp. 763-767
Author(s):  
T. V. Arutyunyan ◽  
A. F. Korystova ◽  
L. N. Kublik ◽  
M. Kh. Levitman ◽  
V. V. Shaposhnikova ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Angiotensin Converting Enzyme ◽  
Reactive Oxygen ◽  
Rat Aorta ◽  
High Salt ◽  
Oxygen Species ◽  
Converting Enzyme ◽  
High Salt Diet ◽  
Salt Diet
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