Basic Aspects of Collagen Metabolism

1997 ◽  
pp. 77-93
Author(s):  
A. Oikarinen
Keyword(s):  
2008 ◽  
Vol 48 ◽  
pp. S190
Author(s):  
J. Wei ◽  
X.L. Zhang ◽  
Z.N. Dun ◽  
S.R. Xie ◽  
J.G. Shen ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yoshihiro Osawa ◽  
Kaho Nomura ◽  
Yoshifumi Kimira ◽  
Seiji Kushibe ◽  
Ken-ichi Takeyama ◽  
...  

AbstractActive collagen oligopeptides (ACOP) are bioactive collagen-derived peptides detected by a recently-established ELISA. To facilitate studies of the function and metabolism of these products, this study aims to determine which of these peptides is recognized by a novel anti-ACOP antibody used in this ELISA. We then investigate the effect of collagen peptide (CP) ingestion and exercise on urinary ACOP concentrations in a cohort of university student athletes using colorimetric, LC–MS/MS, and ELISA. We observed that the antibody showed strong cross-reactivity to Pro-Hyp and Gly-Pro-Hyp and weak cross-reactivity to commercial CP. CP ingestion increased the urinary level of ACOP over time, which correlated highly with urinary levels of peptide forms of Hyp and Pro-Hyp. Physical activity significantly decreased the urinary ACOP level. This study demonstrates changes in urinary ACOP following oral CP intake and physical activity using ELISA with the novel anti-ACOP antibody. Thus, ACOP may be useful as a new biomarker for collagen metabolism.


1970 ◽  
Vol 16 (10) ◽  
pp. 853-855
Author(s):  
Mala Herzberg ◽  
Z Oberman ◽  
O Khermosh ◽  
S L Weissman

Abstract Urinary excretion of hydroxyproline was measured in 12 cases of multiple fractures as an index of bone collagen metabolism. Measurements were made for 10 consecutive days after injury; 10 patients with low back pain served as the control group. With three exceptions, the mean daily excretion of hydroxyproline and the day-to-day variations were within the same range in the group with multiple fractures as in the control group.


2014 ◽  
Vol 394 (1-2) ◽  
pp. 217-224 ◽  
Author(s):  
Anna Galicka ◽  
Rafał Krętowski ◽  
Jolanta Nazaruk ◽  
Marzanna Cechowska-Pasko

1987 ◽  
Vol 46 (2) ◽  
pp. 159-167 ◽  
Author(s):  
John A. Pickrell ◽  
Fletcher F. Hahn ◽  
Alan H. Rebar ◽  
Rebecca A. Horoda ◽  
Rogene F. Henderson

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