The Application of Surface Coils for Tissue Characterization — Demonstrated by the Determination of T2 Relaxation Times

1990 ◽  
pp. 26-30
Author(s):  
J. Gehrig ◽  
R. Bader ◽  
H.-J. Zabel ◽  
W. J. Lorenz
Keyword(s):  
Tissue Characterization ◽  
Relaxation Times ◽  
T2 Relaxation ◽  
Surface Coils

scholarly journals Myocardial Mapping in Systemic Sarcoidosis: A Comparison of Two Measurement Approaches

2020 ◽  
Vol 193 (01) ◽  
pp. 68-76
Author(s):  
Darius Dabir ◽  
Julian Luetkens ◽  
Daniel Kuetting ◽  
Jennifer Nadal ◽  
Hans Heinz Schild ◽  
...  
Keyword(s):  
T1 Mapping ◽  
Tissue Characterization ◽  
Cardiac Involvement ◽  
T2 Mapping ◽  
Relaxation Times ◽  
Short Axis Slice ◽  
T2 Relaxation ◽  
Standard Mapping ◽  
Systemic Sarcoidosis ◽  
T1 And T2

Purpose To investigate if T1 and T2 mapping is able to differentiate between diseased and healthy myocardium in patients with systemic sarcoidosis, and to compare the standard mapping measurement (measurement within the whole myocardium of the midventricular short axis slice, SAX) to a more standardized method measuring relaxation times within the midventricular septum (ConSept). Materials and Methods 24 patients with biopsy-proven extracardiac sarcoidosis and 17 healthy control subjects were prospectively enrolled in this study and underwent CMR imaging at 1.5 T including native T1 and T2 mapping. Patients were divided into patients with (LGE+) and without (LGE–) cardiac sarcoidosis. T1 and T2 relaxation times were compared between patients and controls. Furthermore, the SAX and the ConSept approach were compared regarding differentiation between healthy and diseased myocardium. Results T1 and T2 relaxation times were significantly longer in all patients compared with controls using both the SAX and the ConSept approach (p < 0.05). However, LGE+ and LGE– patients showed no significant differences in T1 and T2 relaxation times regardless of the measurement approach used (ConSept/SAX) (p > 0.05). Direct comparison of ConSept and SAX T1 mapping showed high conformity in the discrimination between healthy and diseased myocardium (Kappa = 0.844). Conclusion T1 and T2 mapping may not only enable noninvasive recognition of cardiac involvement in patients with systemic sarcoidosis but may also serve as a marker for early cardiac involvement of the disease allowing for timely treatment. ConSept T1 mapping represents an equivalent method for tissue characterization in this population compared to the SAX approach. Further studies including follow-up examinations are necessary to confirm these preliminary results. Key Points:  Citation Format

scholarly journals CMR Tissue Characterization in Patients with HFmrEF

2019 ◽  
Vol 8 (11) ◽  
pp. 1877 ◽  
Author(s):  
Patrick Doeblin ◽  
Djawid Hashemi ◽  
Radu Tanacli ◽  
Tomas Lapinskas ◽  
Rolf Gebker ◽  
...  
Keyword(s):  
Cardiac Mri ◽  
Tissue Characterization ◽  
Statistical Significance ◽  
Systolic Dysfunction ◽  
Extracellular Volume ◽  
Relaxation Times ◽  
Healthy Controls ◽  
T2 Relaxation ◽  
Reduced Ejection Fraction ◽  
T1 Relaxation

The characteristics and optimal management of heart failure with a moderately reduced ejection fraction (HFmrEF, LV-EF 40–50%) are still unclear. Advanced cardiac MRI offers information about function, fibrosis and inflammation of the myocardium, and might help to characterize HFmrEF in terms of adverse cardiac remodeling. We, therefore, examined 17 patients with HFpEF, 18 with HFmrEF, 17 with HFrEF and 17 healthy, age-matched controls with cardiac MRI (Phillips 1.5 T). T1 and T2 relaxation time mapping was performed and the extracellular volume (ECV) was calculated. Global circumferential (GCS) and longitudinal strain (GLS) were derived from cine images. GLS (−15.7 ± 2.1) and GCS (−19.9 ± 4.1) were moderately reduced in HFmrEF, resembling systolic dysfunction. Native T1 relaxation times were elevated in HFmrEF (1027 ± 40 ms) and HFrEF (1033 ± 54 ms) compared to healthy controls (972 ± 31 ms) and HFpEF (985 ± 32 ms). T2 relaxation times were elevated in HFmrEF (55.4 ± 3.4 ms) and HFrEF (56.0 ± 6.0 ms) compared to healthy controls (50.6 ± 2.1 ms). Differences in ECV did not reach statistical significance. HFmrEF differs from healthy controls and shares similarities with HFrEF in cardiac MRI parameters of fibrosis and inflammation.

Determination of T1ρ values for head and neck tissues at 0.1 T: a comparison to T1 and T2 relaxation times

1998 ◽  
Vol 16 (4) ◽  
pp. 377-383 ◽  
Author(s):  
Antti T Markkola ◽  
Hannu J Aronen ◽  
Usama Abo Ramadan ◽  
Juha T Halavaara ◽  
Jukka I Tanttu ◽  
...  
Keyword(s):  
Head And Neck ◽  
Relaxation Times ◽  
T2 Relaxation ◽  
T1 And T2

Determination of T1- and T2-relaxation times in the spleen of patients with splenomegaly

1990 ◽  
Vol 8 (1) ◽  
pp. 39-42 ◽  
Author(s):  
C. Thomsen ◽  
P. Josephsen ◽  
H. Karle ◽  
E. Juhl ◽  
P.Grundtvig Sørensen ◽  
...  
Keyword(s):  
Relaxation Times ◽  
T2 Relaxation ◽  
T1 And T2

scholarly journals Case report: epipericardial fat necrosis, a rare cause of chest pain

2021 ◽  
Author(s):  
F M A van den Heuvel ◽  
A C Dimitriu-Leen ◽  
J Habets ◽  
R Nijveldt
Keyword(s):  
Chest Pain ◽  
Ct Angiography ◽  
Tissue Characterization ◽  
Relaxation Times ◽  
Surrounding Tissue ◽  
Fat Necrosis ◽  
T2 Relaxation ◽  
T1 Relaxation ◽  
Ischaemic Attack

Abstract Background Epipericardial fat necrosis (EFN) is a rare cause of chest pain which is often unrecognized. Case summary A 58 year-old male previously known with a transient ischaemic attack presented with a sharp, substernal chest pain. Pulmonary embolism was ruled out by computed tomography (CT) angiography. However, CT angiography revealed an inhomogeneous epipericardial mass. On cardiovascular magnetic resonance imaging (CMR) the mass had an inhomogeneous signal intensity without infiltration of surrounding tissue. Late gadolinium enhancement imaging showed subtle hyperenhancement. Tissue characterization by means of parametric mapping revealed very low native T1 relaxation times and increased T2 relaxation times. In conclusion, the epipericardial mass showed fibro-fatty inflammatory markers, suggestive of EFN. The chest pain resolved spontaneously. Follow up CT 3 months later showed a marked regression of the mass which confirmed the diagnosis EFN. Discussion EFN is a benign and self-limiting inflammatory cause of chest pain which can be diagnosed with multi-modality imaging and must not be overlooked in the differential diagnosis of patients with acute pleuritic chest pain.

Tissue Characterization of Intracranial Tumors by MR Imaging

1991 ◽  
Vol 32 (6) ◽  
pp. 498-504 ◽  
Author(s):  
L. Kjær ◽  
C. Thomsen ◽  
F. Gjerris ◽  
B. Mosdal ◽  
O. Henriksen
Keyword(s):  
Mr Imaging ◽  
Tissue Characterization ◽  
Relaxation Times ◽  
Relaxation Processes ◽  
Intracranial Tumors ◽  
T2 Relaxation ◽  
Experimental Conditions ◽  
Spin Echo Sequence ◽  
Tumor Types

The main purpose of this in vivo study was to provide a detailed description of the T1- and T2-relaxation processes in intracranial tumors at 1.5 T. A total of 100 patients were investigated. Optimal experimental conditions were carefully observed, including the use of long TR values. T1 determination was based on a partial saturation inversion recovery sequence covering 12 or 6 data points. T2 determination involved a multiple spin echo sequence with 32 echoes. Calculations included biexponential analysis of the 12-point T1 data and all T2 data obtained. The results were evaluated in accordance with histopathology. The T1- and the T2-relaxation times of the prevailing tumor types were significantly different (p < 0.0005). However, biologic scatter and overlap between tumor types were considerable. In particular, no discrimination between benign and malignant tumor growth was possible. Biexponential evaluation did not increase the specificity, although a biexponential relaxation behavior was recognized in 37% of the T2 curves. The results indicate that tissue heterogeneity is responsible for most of the scatter in the relaxation times. It is concluded that tissue characterization by MR imaging, based solely on relaxation time measurements, seems to be of no value in the differentiation of intracranial tumors.

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