G-CSF after Intensive Induction Chemotherapy in Refractory Acute Leukemia and Bone Marrow Transplantation in Myeloid Leukemia

1992 ◽  
pp. 101-107 ◽  
Author(s):  
R. Ohno ◽  
T. Masaoka ◽  
S. Asano ◽  
F. Takaku
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Acute Leukemia ◽  
Induction Chemotherapy ◽  
Marrow Transplantation ◽  
Myeloid Leukemia

scholarly journals Allogeneic bone marrow transplantation for acute leukemia refractory to induction chemotherapy

Cancer ◽  
1985 ◽  
Vol 56 (6) ◽  
pp. 1374-1379 ◽  
Author(s):  
Axel R. Zander ◽  
Karel A. Dicke ◽  
Michael Keating ◽  
Lijda Vellekoop ◽  
Steven Culbert ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Acute Leukemia ◽  
Induction Chemotherapy ◽  
Marrow Transplantation ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Allogeneic Bone

scholarly journals Molecular analysis of relapse in chronic myeloid leukemia after allogeneic bone marrow transplantation

Blood ◽  
1987 ◽  
Vol 70 (3) ◽  
pp. 873-876 ◽  
Author(s):  
TS Ganesan ◽  
GL Min ◽  
JM Goldman ◽  
BD Young
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Chronic Myeloid Leukemia ◽  
Marrow Transplantation ◽  
Myeloid Leukemia ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Leukemic Cells ◽  
Allogeneic Bone ◽  
Leukemic Clone

Abstract Four patients with Philadelphia (Ph′) positive chronic myeloid leukemia (CML) were studied before, after, and on relapse following allogeneic bone marrow transplantation (BMT). Southern analysis of DNA from cells collected before and at relapse after BMT was performed in order to investigate the origin of the leukemia at relapse. Using minisatellite probes we showed that the relapse occurred in cells of host origin in all four patients and this was confirmed with a Y chromosome specific probe in two male patients who had a female donor. Furthermore, using two probes for the breakpoint cluster region (bcr) on chromosome 22, we showed that leukemic cells at relapse bore identical rearrangements to those in the disease at time of presentation of each patient. We conclude that relapse in all four patients is due to re-emergence of the original leukemic clone.

scholarly journals Bacterial pneumonia following bone marrow transplantation: HRCT findings

2009 ◽  
Vol 35 (5) ◽  
pp. 431-435 ◽  
Author(s):  
Luiz Otávio de Mattos Coelho ◽  
Taísa Davaus Gasparetto ◽  
Dante Luiz Escuissato
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Myeloid Leukemia ◽  
Bacterial Pneumonia ◽  
Positive Culture ◽  
Lymphocytic Leukemia ◽  
Ground Glass ◽  
Wall Thickening ◽  
Air Space

OBJECTIVE: To describe HRCT findings in patients with bacterial pneumonia following bone marrow transplantation (BMT). METHODS: This was a retrospective study involving 30 patients diagnosed with bacterial pneumonia in whom HRCT of the chest was performed within 24 h after the onset of symptoms and the diagnosis was confirmed, based on a positive culture of sputum or bronchial aspirate, together with a positive pleural fluid or blood culture, within one week after symptom onset. There were 20 male patients and 10 female patients. The median age was 21 years (range, 1-41 years). The BMT had been performed for the treatment of the following: chronic myeloid leukemia, in 14 cases; severe aplastic anemia, in 6; acute myeloid leukemia, in 4; Fanconi's anemia, in 3; and acute lymphocytic leukemia, in 3. Two radiologists analyzed the HRCT scans and reached their final decisions by consensus. RESULTS: The most common HRCT findings were air-space consolidation (in 60%), small centrilobular nodules (in 50%), ground-glass opacities (in 40%), bronchial wall thickening (in 20%), large nodules (in 20%), pleural lesions (in 16.7%) and tree-in-bud opacities (in 10%). The pulmonary lesions were distributed in the central and peripheral areas in 15 patients, whereas they were exclusively peripheral in 11. Lesions were located in the lower and middle lobes of the lung in 22 and 20 patients, respectively. CONCLUSIONS: The most common HRCT findings in our patient sample were air-space consolidation, small centrilobular nodules and ground-glass opacities, most often in the central and peripheral regions of the middle and lower lung zones.

Allogeneic Bone Marrow Transplantation Versus Chemotherapy in Children with Acute Leukemia in Sweden

1989 ◽  
Vol 6 (2) ◽  
pp. 137-144 ◽  
Author(s):  
Olle Ringden ◽  
Per Bolme ◽  
Berit Lönnqvist ◽  
Göran Gustafsson ◽  
Anders Kreilger
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Acute Leukemia ◽  
Marrow Transplantation ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Allogeneic Bone

T-cell depleted (TCD) bone marrow transplantation (BMT) for acute leukemia (AL) and chronic granulocytic leukemia (CGL)

1986 ◽  
Vol 10 (1) ◽  
pp. 123
Author(s):  
J.Y. Cahn ◽  
P. Hervé ◽  
M. Flesch ◽  
E. Plouvier ◽  
E. Racadot ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
T Cell ◽  
Acute Leukemia ◽  
Marrow Transplantation ◽  
Chronic Granulocytic Leukemia ◽  
Granulocytic Leukemia
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