A New Strategy for Studying Microtubule Transport and Assembly During Axon Growth

1998 ◽  
pp. 155-170
Author(s):  
Peter W. Baas
Keyword(s):  
Axon Growth ◽  
Microtubule Transport ◽  
New Strategy

scholarly journals Microtubule transport and assembly during axon growth.

1996 ◽  
Vol 133 (1) ◽  
pp. 151-157 ◽  
Author(s):  
W Yu ◽  
M J Schwei ◽  
P W Baas
Keyword(s):  
Axon Growth ◽  
Composite Model ◽  
Cultured Neurons ◽  
Cell Biol ◽  
Novel Approach ◽  
Microtubule Transport

There is controversy concerning the mechanisms by which the axonal microtubule (MT) array is elaborated, with some models focusing on MT assembly and other models focusing on MT transport. We have proposed a composite model in which MT assembly and transport are both important (Joshi, H.C., and P.W. Baas. 1993. J. Cell Biol. 121:1191-1196). In the present study, we have taken a novel approach to evaluate the merits of this proposal. Biotinylated tubulin was microinjected into cultured neurons that had already grown short axons. The axons were then permitted to grow longer, after which the cells were prepared for immunoelectron microscopic analyses. We reasoned that any polymer that assembled or turned over subunits after the introduction of the probe should label for biotin, while any polymer that was already assembled but did not turnover should not label. Therefore, the presence in the newly grown region of the axon of any unlabeled MT polymer is indicative of MT transport. In sampled regions, the majority of the polymer was labeled, indicating that MT assembly events are active during axon growth. Varying amounts of unlabeled polymer were also present in the newly grown regions, indicating that MT transport also occurs. Together these findings demonstrate that MT assembly and transport both contribute to the elaboration of the axonal MT array.

A new strategy for prenatal diagnosis in a sporadic haemophilia B family

Haemophilia ◽  
2001 ◽  
Vol 7 (4) ◽  
pp. 416-418 ◽  
Author(s):  
M. Acquila ◽  
F. Bottini ◽  
A. Valetto ◽  
D. Caprino ◽  
P. G. Mori ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Haemophilia B ◽  
New Strategy

Guidelines Bring New Strategy in Low-Risk AF

2012 ◽  
Vol 45 (15) ◽  
pp. 12-13
Author(s):  
BRUCE JANCIN
Keyword(s):  
Low Risk ◽  
New Strategy

New Strategy for the Synthesis of 2-Deoxy-C-aryl-nucleoside Frameworks

2006 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
S.M. Mahalingam ◽  
S. Vijayasaradhi ◽  
I.S. Aidhen
Keyword(s):  
New Strategy

Practice Directorate: Practice Directorate pursues new strategy

1995 ◽  
Author(s):  
Scott Sleek ◽  
Keyword(s):  
New Strategy

New strategy to search lead compounds with unique structures from plants

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
T Villani ◽  
K Gustafson ◽  
J Zhen ◽  
JE Simon ◽  
Q Wu
Keyword(s):  
Lead Compounds ◽  
New Strategy

Latin America in Difficult Search of Its Way

2004 ◽  
pp. 107-117
Author(s):  
Z. Romanova
Keyword(s):  
Latin America ◽  
Demographic Structure ◽  
Financial Problems ◽  
Strategy Of Development ◽  
Small Countries ◽  
New Strategy

The article is devoted to the analysis of economic and financial problems and contradictions accumulated in Latin America under conditions of globalization and market liberation. The originated unfavorable changes gave rise to the need of policy correction in big and small countries. The author analyses a new strategy of development adequate for Latin America with its specific geopolitical situation, demographic structure and history.

Reducing Corner Cracks With a New Strategy for Secondary Cooling

2020 ◽  
Author(s):  
A. Mittermair ◽  
S. Lim ◽  
W. Cho ◽  
P. Pennerstorfer
Keyword(s):  
Secondary Cooling ◽  
New Strategy ◽  
Corner Cracks

Afforestation with multi utility plants – A new strategy for Conservation of Biodiversity

2012 ◽  
Vol 3 (6) ◽  
pp. 35-41
Author(s):  
Dr. Jyoti S Kawalekar ◽  
Keyword(s):  
New Strategy ◽  
Conservation Of Biodiversity

Popes, Saints, Beato Bones and other Images at War

2011 ◽  
Vol 5 (3) ◽  
pp. 337-364
Author(s):  
Kristin Norget
Keyword(s):  
San Francisco ◽  
Catholic Church ◽  
Roman Catholic ◽  
Moral Authority ◽  
Roman Catholic Church ◽  
Critical Examination ◽  
Peripheral Populations ◽  
New Strategy ◽  
Catholic History ◽  
Local Cultures

This article explores new political practices of the Roman Catholic Church by means of a close critical examination of the beatification of the Martyrs of Cajonos, two indigenous men from the Mexican village of San Francisco Cajonos, Oaxaca, in 2002. The Church’s new strategy to promote an upsurge in canonizations and beatifications forms part of a “war of images,” in Serge Gruzinski’s terms, deployed to maintain apparently peripheral populations within the Church’s central paternalistic fold of social and moral authority and influence, while at the same time as it must be seen to remain open to local cultures and realities. In Oaxaca and elsewhere, this ecclesiastical technique of “emplacement” may be understood as an attempt to engage indigenous-popular religious sensibilities and devotion to sacred images while at the same time implicitly trying to contain them, weaving their distinct local historical threads seamlessly into the fabric of a global Catholic history.

Sign in / Sign up

Export Citation Format

Share Document