Inflammation-Mediated Damage as a Potential Therapeutic Target in Acute Ischemic Stroke

2004 ◽  
pp. 185-204 ◽  
Author(s):  
Á. Chamorro ◽  
A. M. Planas
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Therapeutic Target ◽  
Potential Therapeutic Target

Inflammation as a Therapeutic Target in Acute Ischemic Stroke Treatment

2009 ◽  
Vol 9 (14) ◽  
pp. 1240-1260 ◽  
Author(s):  
Antonino Tuttolomondo ◽  
Riccardo Di Sciacca ◽  
Domenico Di Raimondo ◽  
Chiara Renda ◽  
Antonio Pinto ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Therapeutic Target ◽  
Stroke Treatment

Neuron Protection as a Therapeutic Target in Acute Ischemic Stroke

2009 ◽  
Vol 9 (14) ◽  
pp. 1317-1334 ◽  
Author(s):  
Antonino Tuttolomondo ◽  
Riccardo Di Sciacca ◽  
Domenico Di Raimondo ◽  
Valentina Arnao ◽  
Chiara Renda ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Therapeutic Target

scholarly journals Detrimental and Beneficial Effect of Autophagy and a Potential Therapeutic Target after Ischemic Stroke

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Meng Wang ◽  
Hangil Lee ◽  
Kenneth Elkin ◽  
Redina Bardhi ◽  
Longfei Guan ◽  
...  
Keyword(s):  
Cell Death ◽  
Ischemic Stroke ◽  
Therapeutic Target ◽  
Ischemic Injury ◽  
Potential Therapeutic Target ◽  
Physiologic Mechanism ◽  
Promote Cell Survival ◽  
Cellular Components ◽  
Neuroprotective Therapies

Autophagy, a physiologic mechanism that promotes energy recycling and orderly degradation through self-regulated disassembly of cellular components, helps maintain homeostasis. A series of evidences suggest that autophagy is activated as a response to ischemia and has been well-characterized as a therapeutic target. However, the role of autophagy after ischemia remains controversial. Activated-autophagy can remove necrotic substances against ischemic injury to promote cell survival. On the contrary, activation of autophagy may further aggravate ischemic injury, causing cell death. Therefore, the present review will examine the current understanding of the precise mechanism and role of autophagy in ischemia and recent neuroprotective therapies on autophagy, drug therapies, and nondrug therapies, including electroacupuncture (EA).

Kv1.3 Lymphocyte Potassium Channel Inhibition as a Potential Novel Therapeutic Target in Acute Ischemic Stroke

2014 ◽  
Vol 13 (5) ◽  
pp. 801-806 ◽  
Author(s):  
Andras Folyovich ◽  
Eniko Biro ◽  
Csaba Orban ◽  
Anna Bajnok ◽  
Barna Vasarhelyi ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Potassium Channel ◽  
Acute Ischemic Stroke ◽  
Therapeutic Target ◽  
Channel Inhibition ◽  
Novel Therapeutic

scholarly journals Microglia-associated neuroinflammation is a potential therapeutic target for ischemic stroke

2021 ◽  
Vol 16 (1) ◽  
pp. 6
Author(s):  
Ai-Ping Wang ◽  
Ying Tian ◽  
Wan Zhang ◽  
Tian Tian ◽  
Shao-Xin Gong ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Therapeutic Target ◽  
Potential Therapeutic Target

scholarly journals Tau as a potential therapeutic target for ischemic stroke

Aging ◽  
2019 ◽  
Vol 11 (24) ◽  
pp. 12827-12843 ◽  
Author(s):  
Xin Chen ◽  
Hua Jiang
Keyword(s):  
Ischemic Stroke ◽  
Therapeutic Target ◽  
Potential Therapeutic Target

scholarly journals AMPK: Potential Therapeutic Target for Ischemic Stroke

Theranostics ◽  
2018 ◽  
Vol 8 (16) ◽  
pp. 4535-4551 ◽  
Author(s):  
Shuai Jiang ◽  
Tian Li ◽  
Ting Ji ◽  
Wei Yi ◽  
Zhi Yang ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Therapeutic Target ◽  
Potential Therapeutic Target

Osteopontin as a Potential Therapeutic Target for Ischemic Stroke

2017 ◽  
Vol 14 (6) ◽  
Author(s):  
Qiquan Zhu ◽  
Xu Luo ◽  
Jie Zhang ◽  
Yun Liu ◽  
Hansheng Luo ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Therapeutic Target ◽  
Potential Therapeutic Target
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