Post-network immunology: Idiotypic network continues at the bedside

2008 ◽  
pp. 124-132
Keyword(s):  
Idiotypic Network

Behavior of the Idiotypic Network in Conventional Immune Responses

1994 ◽  
Vol 159 (1) ◽  
pp. 40-48 ◽  
Author(s):  
Mariangela Segre ◽  
Diego Segre
Keyword(s):  
Immune Responses ◽  
Idiotypic Network

scholarly journals Generation of Her-2/neu vaccine utilizing idiotypic network cascade

2007 ◽  
Vol 6 (12) ◽  
pp. 1916-1925 ◽  
Author(s):  
Smarajit Pal ◽  
Asim Saha ◽  
Kartik Mohanty ◽  
Palash Mallick ◽  
Sunil K. Chatterjee ◽  
...  
Keyword(s):  
Idiotypic Network ◽  
Her 2

scholarly journals Naturally induced auto-anit-idiotypic antibodies. Induction by identical idiotopes in some members of an outbred rabbit family.

1982 ◽  
Vol 156 (3) ◽  
pp. 860-872 ◽  
Author(s):  
S B Binion ◽  
L S Rodkey
Keyword(s):  
Germ Line ◽  
Antibody Responses ◽  
Idiotypic Network ◽  
Paternal Origin ◽  
Cross Reactions ◽  
Network Concept ◽  
Normal Individuals ◽  
Micrococcus Lysodeikticus ◽  
The Cross ◽  
Antibody Population

Naturally induced auto-anti-idiotypic (AAI) antibody responses specific for antimicrococcal antibody idiotypes were detected in 42% of the rabbits in a family immunized with Micrococcus lysodeikticus. The natural AAI response of each rabbit recognized only a portion (11-41%) of that individual's total antimicrococcal antibody population. Cross-reactions of idiotypes were observed within the group of rabbits exhibiting natural AAI responses. Examination of the basis for the cross-reactions showed that the natural AAI antisera recognized identical idiotopes on the antimicrococcal F(ab')2 fragments from each rabbit that made an AAI response. The cross-reactive idiotopes were shown to be of paternal origin and were found in the antimicrococcal antibodies of each offspring. The data strongly support the idiotypic network concept that naturally induced AAI responses may occur routinely in outbred normal individuals as a result of antigenic stimulation. Further, the data suggest that the induction of regulatory AAI antibody responses in outbred rabbits may depend on the expression of particular germ line idiotopes.

Correlation between immune maturation and idiotypic network recognition

1996 ◽  
Vol 26 (9) ◽  
pp. 2234-2242 ◽  
Author(s):  
Hans Lange ◽  
Meika Solterbeck ◽  
Claudia Berek ◽  
Hilmar Lemke
Keyword(s):  
Idiotypic Network ◽  
Immune Maturation

Some remarks on the stability of the idiotypic network

1977 ◽  
Vol 14 (11-12) ◽  
pp. 733-739 ◽  
Author(s):  
J Hiernaux
Keyword(s):  
Idiotypic Network ◽  
The Stability

scholarly journals Unreasonable implications of reasonable idiotypic network assumptions

1989 ◽  
Vol 51 (3) ◽  
pp. 381-408 ◽  
Author(s):  
R DEBOER ◽  
P HOGEWEG
Keyword(s):  
Idiotypic Network

Idiotypic Network Among T Cells

1985 ◽  
pp. 302-303
Author(s):  
Klaus Fey ◽  
Klaus Eichmann
Keyword(s):  
T Cells ◽  
Idiotypic Network
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