Molecular Dissection of Regulatory Light Chain Function in Vertebrate Smooth Muscle Myosins

1995 ◽  
pp. 111-130
Author(s):  
John Kendrick-Jones ◽  
Tony Rowe ◽  
Ana C. Rasera da Silva ◽  
Fernando C. Reinach
Keyword(s):  
Smooth Muscle ◽  
Light Chain ◽  
Regulatory Light Chain ◽  
Molecular Dissection

scholarly journals Function of the NH2-terminal domain of the regulatory light chain on the regulation of smooth muscle myosin.

1994 ◽  
Vol 269 (45) ◽  
pp. 28173-28180
Author(s):  
M Ikebe ◽  
R Ikebe ◽  
H Kamisoyama ◽  
S Reardon ◽  
J P Schwonek ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Light Chain ◽  
Regulatory Light Chain ◽  
Smooth Muscle Myosin ◽  
Terminal Domain ◽  
Muscle Myosin

Differential expression and effect of 1,25-dihydroxyvitamin D3 on myosin in arterial tree of rats

1995 ◽  
Vol 269 (2) ◽  
pp. C443-C450 ◽  
Author(s):  
K. Ishibashi ◽  
A. Evans ◽  
T. Shingu ◽  
K. Bian ◽  
R. D. Bukoski
Keyword(s):  
Smooth Muscle ◽  
Heavy Chain ◽  
Light Chain ◽  
Myosin Light Chain ◽  
Regulatory Light Chain ◽  
Myosin Regulatory Light Chain ◽  
Arterial Tree ◽  
Dihydroxyvitamin D3 ◽  
1,25 Dihydroxyvitamin D3 ◽  
Wistar Kyoto

The hypothesis that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3, also known as calcitriol] modulates myosin expression in vascular smooth muscle was tested. Wistar-Kyoto or spontaneously hypertensive rats given intraperitoneal injections of 25 ng 1,25(OH)2D3/100 g body weight for varying periods of time showed a greater than twofold increase in aortic mRNA encoding the myosin regulatory light chain relative to 18S rRNA (P < 0.05). 1,25(OH)2D3 administration to Wistar rats caused a significant increase in the aortic content of total myosin regulatory light chain and total myosin heavy chain. The increase in myosin light chain was the result of a specific increase in expression of its smooth muscle isoform [control = 65.2 +/- 3.4% vs. 1,25(OH)2D3 = 78.7 +/- 3.6%, P = 0.020]. 1,25(OH)2D3 had no effect on total myosin light chain or heavy chain in the superior mesenteric artery. The hormone did, however, increase the proportion of the smooth muscle isoform of the light chain in this vessel [control = 81.4 +/- 2.6% vs. 1,25(OH)2D3 = 88.8 +/- 2.1%, P = 0.048]. In branch II and III mesenteric resistance arteries, 1,25(OH)2D3 significantly increased the active stress response to 10 mumol/l norepinephrine but was without effect on total myosin light chain or heavy chain content or on the relative expression of the myosin light chain isoforms [control = 94.0 +/- 1.4% vs. 1,25(OH)2D3 = 95.8 +/- 1.1%, P = 0.33].(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Using the SpyTag SpyCatcher system to label smooth muscle myosin II filaments with a quantum dot on the regulatory light chain

Cytoskeleton ◽  
2019 ◽  
Vol 76 (2) ◽  
pp. 192-199 ◽  
Author(s):  
Richard K. Brizendine ◽  
Murali Anuganti ◽  
Christine R. Cremo
Keyword(s):  
Smooth Muscle ◽  
Quantum Dot ◽  
Light Chain ◽  
Myosin Ii ◽  
Regulatory Light Chain ◽  
Smooth Muscle Myosin ◽  
Muscle Myosin

scholarly journals Myosin Regulatory Light Chain Phosphorylation and Strain Modulate Adenosine Diphosphate Release from Smooth Muscle Myosin

2004 ◽  
Vol 86 (4) ◽  
pp. 2318-2328 ◽  
Author(s):  
Alexander S. Khromov ◽  
Martin R. Webb ◽  
Michael A. Ferenczi ◽  
David R. Trentham ◽  
Andrew P. Somlyo ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Light Chain ◽  
Adenosine Diphosphate ◽  
Regulatory Light Chain ◽  
Smooth Muscle Myosin ◽  
Myosin Regulatory Light Chain ◽  
Muscle Myosin ◽  
Regulatory Light Chain Phosphorylation

scholarly journals 3L1330 X-ray diffraction from the complex between actin and smooth muscle S1 with regulatory light chain labeled with metal cluster

2002 ◽  
Vol 42 (supplement2) ◽  
pp. S187
Author(s):  
H. Iwamoto ◽  
K. Oiwa ◽  
J. Wakayama ◽  
T. Tamura ◽  
T. Fujisawa
Keyword(s):  
Smooth Muscle ◽  
Light Chain ◽  
Metal Cluster ◽  
Regulatory Light Chain ◽  
X Ray Diffraction ◽  
X Ray
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