Granule Cell Migration and Differentiation

2013 ◽  
pp. 107-125 ◽  
Author(s):  
Yutaro Komuro ◽  
Jennifer K. Fahrion ◽  
Kathryn D. Foote ◽  
Kathleen B. Fenner ◽  
Tatsuro Kumada ◽  
...  
Keyword(s):  
Cell Migration ◽  
Granule Cell

Role of PACAP in Controlling Granule Cell Migration

2009 ◽  
Vol 8 (4) ◽  
pp. 433-440 ◽  
Author(s):  
Donald Bryant Cameron ◽  
Emilie Raoult ◽  
Ludovic Galas ◽  
Yulan Jiang ◽  
Kimberly Lee ◽  
...  
Keyword(s):  
Cell Migration ◽  
Granule Cell

scholarly journals Erratum: Corrigendum: A role for Bicaudal-D2 in radial cerebellar granule cell migration

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Dick Jaarsma ◽  
Robert van den Berg ◽  
Phebe S. Wulf ◽  
Susan van Erp ◽  
Nanda Keijzer ◽  
...  
Keyword(s):  
Cell Migration ◽  
Granule Cell ◽  
Cerebellar Granule Cell ◽  
Cerebellar Granule

Experimental modification of postnatal cerebellar granule cell migration in vitro

1986 ◽  
Vol 377 (2) ◽  
pp. 298-304 ◽  
Author(s):  
Ju¨rgen Lindner ◽  
Gerhard Zinser ◽  
William Werz ◽  
Christo Goridis ◽  
Bernard Bizzini ◽  
...  
Keyword(s):  
Cell Migration ◽  
Granule Cell ◽  
Cerebellar Granule Cell ◽  
Cerebellar Granule ◽  
Experimental Modification

Developmental expression of the α6 GABAA receptor subunit mRNA occurs only after cerebellar granule cell migration

1993 ◽  
Vol 75 (1) ◽  
pp. 91-103 ◽  
Author(s):  
Tian Zheng ◽  
Maria-Rita Santi ◽  
Patrizia Bovolin ◽  
Lionel N.J-L. Marlier ◽  
Dennis R. Grayson
Keyword(s):  
Cell Migration ◽  
Gabaa Receptor ◽  
Granule Cell ◽  
Cerebellar Granule Cell ◽  
Developmental Expression ◽  
Receptor Subunit ◽  
Cerebellar Granule ◽  
Subunit Mrna

The Role of Galanin in Cerebellar Granule Cell Migration in the Early Postnatal Mouse during Normal Development and After Injury

2021 ◽  
pp. JN-RM-0900-15
Author(s):  
Yutaro Komuro ◽  
Ludovic Galas ◽  
Yury M. Morozov ◽  
Jennifer K. Fahrion ◽  
Emilie Raoult ◽  
...  
Keyword(s):  
Cell Migration ◽  
Granule Cell ◽  
Normal Development ◽  
Cerebellar Granule Cell ◽  
Cerebellar Granule

Role of Pax6 in development of the cerebellar system

Development ◽  
1999 ◽  
Vol 126 (16) ◽  
pp. 3585-3596 ◽  
Author(s):  
D. Engelkamp ◽  
P. Rashbass ◽  
A. Seawright ◽  
V. van Heyningen
Keyword(s):  
Cell Proliferation ◽  
Cell Migration ◽  
Granule Cell ◽  
Granule Cells ◽  
Cerebellar Granule Cells ◽  
Long Distance ◽  
Cerebellar Granule ◽  
Precerebellar Nuclei ◽  
Rhombic Lip

Post-mitotic neurons generated at the rhombic lip undertake long distance migration to widely dispersed destinations, giving rise to cerebellar granule cells and the precerebellar nuclei. Here we show that Pax6, a key regulator in CNS and eye development, is strongly expressed in rhombic lip and in cells migrating away from it. Development of some structures derived from these cells is severely affected in Pax6-null Small eye (Pax6(Sey)/Pax6(Sey)) embryos. Cell proliferation and initial differentiation seem unaffected, but cell migration and neurite extension are disrupted in mutant embryos. Three of the five precerebellar nuclei fail to form correctly. In the cerebellum the pre-migratory granule cell sub-layer and fissures are absent. Some granule cells are found in ectopic positions in the inferior colliculus which may result from the complete absence of Unc5h3 expression in Pax6(Sey)/Pax6(Sey) granule cells. Our results suggest that Pax6 plays a strong role during hindbrain migration processes and at least part of its activity is mediated through regulation of the netrin receptor Unc5h3.

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