Embryonic Stem Cells: The Role of Nitric Oxide in Regulating Cell Differentiation, Self-Renewal, and Apoptosis

2011 ◽  
pp. 359-369 ◽  
Author(s):  
Juan R. Tejedo ◽  
Gladys M. Cahuana ◽  
Francisco J. Bedoya ◽  
Rafael Tapia-Limonchi
Keyword(s):  
Nitric Oxide ◽  
Stem Cells ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Self Renewal

The role of nitric oxide in cardiomyogenesis using embryonic stem cells

2004 ◽  
Vol 23 (2) ◽  
pp. S173
Author(s):  
L.L Shears ◽  
S Kanno ◽  
R.L Kormos ◽  
K.R McCurry ◽  
T.R Billiar
Keyword(s):  
Nitric Oxide ◽  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem

Role of Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells in mice in vitro

Zygote ◽  
2013 ◽  
Vol 22 (4) ◽  
pp. 513-520 ◽  
Author(s):  
I. Bahena ◽  
E. Xu ◽  
M. Betancourt ◽  
E. Casas ◽  
Y. Ducolomb ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Germ Cell ◽  
Embryonic Stem ◽  
Oocyte Growth ◽  
Germ Cell Differentiation ◽  
Rnai Technology

SummaryIn a previous study, we have identified a set of conserved spermatogenic genes whose expression is restricted to testis and ovary and that are developmentally regulated. One of these genes, the transcription factor Mael, has been reported to play an essential role in mouse spermatogenesis. Nevertheless, the role of Mael in mouse oogenesis has not been defined. In order to analyse the role of Mael in mouse oogenesis, the expression of this gene was blocked during early oogenesis in mouse in vitro using RNAi technology. In addition, the role of Mael during differentiation of embryonic stem cells (ESC) into germ cells in vitro was analysed. Results show that downregulation of Mael by a specific short interfering RNA disrupted fetal oocyte growth and differentiation in fetal ovary explants in culture and the expression of several germ-cell markers in ESC during their differentiation. These results suggest that there is an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells in mouse in vitro.

New Proteomic Insights on the Role of NPR-A in Regulating Self-Renewal of Embryonic Stem Cells

2014 ◽  
Vol 10 (4) ◽  
pp. 561-572 ◽  
Author(s):  
Sameh Magdeldin ◽  
Tadashi Yamamoto ◽  
Ikuo Tooyama ◽  
Essam M. Abdelalim
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Self Renewal

scholarly journals The role of Ca2+ signaling on the self-renewal and neural differentiation of embryonic stem cells (ESCs)

Cell Calcium ◽  
2016 ◽  
Vol 59 (2-3) ◽  
pp. 67-74 ◽  
Author(s):  
Baixia Hao ◽  
Sarah E. Webb ◽  
Andrew L. Miller ◽  
Jianbo Yue
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Neural Differentiation ◽  
Embryonic Stem ◽  
The Self ◽  
Self Renewal

scholarly journals Role of Nitric Oxide Signaling in Endothelial Differentiation of Embryonic Stem Cells

2010 ◽  
Vol 19 (10) ◽  
pp. 1617-1626 ◽  
Author(s):  
Ngan F. Huang ◽  
Felix Fleissner ◽  
John Sun ◽  
John P. Cooke
Keyword(s):  
Nitric Oxide ◽  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Endothelial Differentiation ◽  
Nitric Oxide Signaling
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