Determination of the endonuclease and methylase content of Neisseria gonorrhoeae strain P9 and the cloning therefrom of two functional methylase genes

1988 ◽  
pp. 329-334 ◽  
Author(s):  
K. M. Sullivan ◽  
J. R. Saunders
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Gonorrhoeae Strain

scholarly journals Clinical Neisseria gonorrhoeae isolate with a N. meningitidis porA gene and no prolyliminopeptidase activity, Sweden, 2011 – danger of false-negative genetic and culture diagnostic results

2012 ◽  
Vol 17 (9) ◽  
Author(s):  
D Golparian ◽  
E Johansson ◽  
M Unemo
Keyword(s):  
Neisseria Gonorrhoeae ◽  
False Negative ◽  
Gonorrhoeae Strain ◽  
Negative Results ◽  
False Negative Results ◽  
Gonorrhoeae Isolate

We describe a Neisseria gonorrhoeae strain, found in Sweden in 2011, that harbours a N. meningitidis porA gene causing false-negative results in PCRs targeting the gonococcal porA pseudogene. Furthermore, the strain had no prolyliminopeptidase (PIP) activity that many commercial biochemical kits for species verification in culture rely on. Enhanced awareness of the spread of such strains and screening for them can be crucial.

scholarly journals Synthesis of New Oxindoles and Determination of Their Antibacterial Properties

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Pablo E. Romo ◽  
Braulio Insuasty ◽  
Rodrigo Abonia ◽  
María del Pilar Crespo ◽  
Jairo Quiroga
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Neisseria Gonorrhoeae ◽  
Room Temperature ◽  
Antibacterial Properties ◽  
Analytical Techniques ◽  
Toluenesulfonic Acid ◽  
Antistaphylococcal Activity ◽  
New Compounds

A versatile method for the synthesis of new oxindoles was developed by the reaction between substituted isatins and 5-aminopyrazoles. The reaction was carried out at room temperature in ethanol using p-toluenesulfonic acid as the catalyst. The products were obtained with acceptable to excellent yields (44–96%). Structures of the new compounds were unambiguously established by spectroscopic and analytical techniques. The antibacterial activity was determined by microdilution assays. Compounds 3b, 3e, and 3g showed antistaphylococcal activity, particularly compound 3e displayed a potent activity against the vancomycin intermediate Staphylococcus aureus (VISA). Compounds 3i, 3j, and 3o inhibited Neisseria gonorrhoeae growth.

scholarly journals Epitope determination of immunogenic proteins of Neisseria gonorrhoeae

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180962
Author(s):  
Daniel O. Connor ◽  
Lena Danckert ◽  
Sebastian Hoppe ◽  
Frank F. Bier ◽  
Markus von Nickisch-Rosenegk
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Immunogenic Proteins

scholarly journals A Neisseria gonorrhoeae strain with a meningococcal mtrR sequence

2014 ◽  
Vol 63 (8) ◽  
pp. 1113-1115 ◽  
Author(s):  
Ella Trembizki ◽  
Christine Doyle ◽  
Amy Jennison ◽  
Helen Smith ◽  
John Bates ◽  
...  
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Gonorrhoeae Strain

scholarly journals First Neisseria gonorrhoeae strain with resistance to cefixime causing gonorrhoea treatment failure in Austria, 2011

2011 ◽  
Vol 16 (43) ◽  
Author(s):  
M Unemo ◽  
D Golparian ◽  
A Stary ◽  
A Eigentler
Keyword(s):  
Public Health ◽  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Neisseria Gonorrhoeae ◽  
Treatment Failure ◽  
Effective Treatment ◽  
Therapeutic Failure ◽  
Health Control ◽  
Gonorrhoeae Strain ◽  
The United Kingdom

We describe the first cefixime-resistant Neisseria gonorrhoeae strain in Austria that caused treatment failure. It follows the first five cases in Europe of cefixime treatment failure, reported in Norway in 2010 and the United Kingdom in 2011. Effective treatment of gonorrhoea is crucial for public health control and, at present, requires substantially enhanced awareness, more frequent test-of-cure, interaction with experts after therapeutic failure, tracing and therapy of contacts, and surveillance of gonococcal antimicrobial resistance and treatment failures worldwide.

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