Role of Prophylactic Mastectomy

1991 ◽  
pp. 135-148 ◽  
Author(s):  
Mary Jane Houlihan ◽  
Robert M. Goldwyn
Keyword(s):  
Prophylactic Mastectomy

The role of sentinel lymph node biopsy in women undergoing prophylactic mastectomy

2000 ◽  
Vol 180 (4) ◽  
pp. 274-277 ◽  
Author(s):  
Elisabeth L Dupont ◽  
M.Ann Kuhn ◽  
Christa McCann ◽  
Chris Salud ◽  
Janet L Spanton ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Prophylactic Mastectomy ◽  
Lymph Node Biopsy ◽  
Node Biopsy

The Role of Contralateral Prophylactic Mastectomy in Invasive Lobular Carcinoma

1997 ◽  
Vol 3 (1) ◽  
pp. 2-6 ◽  
Author(s):  
Gildy V. Babiera ◽  
Andrew M. Lowy ◽  
B. Scott Davidson ◽  
S. Eva Singletary
Keyword(s):  
Invasive Lobular Carcinoma ◽  
Prophylactic Mastectomy ◽  
Lobular Carcinoma ◽  
Contralateral Prophylactic Mastectomy

scholarly journals Role of Sentinel Lymph Node Biopsy During Contralateral Prophylactic Mastectomy

2020 ◽  
Vol 21 (2) ◽  
pp. 97-103
Author(s):  
Halil Kara ◽  
Akif Enes Arıkan ◽  
Onur Dülgeroğlu ◽  
Cihan Uras
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Prophylactic Mastectomy ◽  
Contralateral Prophylactic Mastectomy ◽  
Lymph Node Biopsy ◽  
Node Biopsy

Bilateral Breast Reconstruction and the Role of Prophylactic Mastectomy

2002 ◽  
Vol 16 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Susan E. MacLennan
Keyword(s):  
Breast Reconstruction ◽  
Prophylactic Mastectomy

THE CURRENT ROLE OF PROPHYLACTIC MASTECTOMY

1996 ◽  
Vol 76 (2) ◽  
pp. 231-242 ◽  
Author(s):  
Marvin J. Lopez ◽  
Kathaleen A. Porter
Keyword(s):  
Prophylactic Mastectomy ◽  
Current Role

The Emerging Role of Prophylactic Mastectomy

2014 ◽  
pp. 129-136
Author(s):  
Pamela R. Portschy ◽  
Todd M. Tuttle
Keyword(s):  
Prophylactic Mastectomy

scholarly journals Impact of Age, Rurality and Distance in Predicting Contralateral Prophylactic Mastectomy for Breast Cancer in a Midwestern state: A Population-Based Study

2020 ◽  
Author(s):  
Ingrid Lizarraga ◽  
Amanda R Kahl ◽  
Ellie Jacoby ◽  
Mary E Charlton ◽  
Charles F Lynch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Rural Women ◽  
Prophylactic Mastectomy ◽  
Contralateral Prophylactic Mastectomy ◽  
The United States ◽  
Population Based ◽  
Travel Distance ◽  
Unilateral Breast Cancer

Abstract Background: There is substantial variability in the use of contralateral prophylactic mastectomy (CPM) in women with unilateral breast cancer across the United States. Iowa is one of several rural Midwestern states found to have the highest proportions of CPM nationally in women <45 years of age. We evaluated the role of rurality and travel distance as factors related to these surgical patterns.Methods: Women with unilateral breast cancer (2007-2017) were identified using Iowa Cancer Registry records. Patients and treating hospitals were classified as metro, nonmetro and rural based on Rural-Urban Continuum Codes. Differences in patient, tumor, and treatment characteristics and median travel distances (MTD) were compared. Characteristics associated with CPM were evaluated with multivariate logistic regression.Results: 22,158 women were identified: 57% metro, 26% nonmetro and 18% rural. The overall proportion of CPM in Iowa was consistently higher than in the national Surveillance, Epidemiology, and End Results (SEER18) throughout the interval from 2007-2015. Young rural women had the highest proportion of CPM (<40 years: 52%, 39% and 40% for rural, metro, nonmetro, respectively). Half of all rural women had surgery at metro hospitals; these women had the longest MTD (56 miles). Of all women treated at metro hospitals, rural women had the highest proportion with CPM (17% rural; vs 14% metro/nonmetro, p=0.007). On multivariate analysis, traveling ≥50 miles (ORs 1.48-2.34) or being rural regardless of travel distance was predictive of CPM (OR = 1.36). Other risk factors were young age (<40 years: OR=7.18, 95% CI: 5.89-8.76) and surgery at a metro hospital that offers reconstruction (OR=2.3, 95% CI: 1.70-3.21) and is not NCI-designated (OR=2.19, 95% CI: 1.78-2.69).Conclusion: There is an unexpectedly high proportion of CPM use in young rural women in Iowa. Travel ≥50 miles and rural residence are independently associated with likelihood of CPM. Disparities in access to specialty care may underlie the desire for surgery that is perceived to minimize follow-up visits.

scholarly journals Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer Who Are Genetic Carriers, Have a Strong Family History or Are just Young at Presentation

Cancers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 140 ◽  
Author(s):  
Victoria Teoh ◽  
Marios-Konstantinos Tasoulis ◽  
Gerald Gui
Keyword(s):  
Breast Cancer ◽  
Contralateral Breast Cancer ◽  
Prophylactic Mastectomy ◽  
Contralateral Prophylactic Mastectomy ◽  
Risk Groups ◽  
Genetic Mutation ◽  
Contralateral Breast ◽  
Strong Family History ◽  
Unilateral Breast Cancer

The uptake of contralateral prophylactic mastectomy is rising with increasing trends that are possibly highest in the USA. Whilst its role is generally accepted in carriers of recognized high-risk predisposition genes such as BRCA1 and BRCA2 when the affected individual is premenopausal, controversy surrounds the benefit in less understood risk-profile clinical scenarios. This comprehensive review explores the current evidence underpinning the role of contralateral prophylactic mastectomy and its impact on contralateral breast cancer risk and survival in three distinct at-risk groups affected by unilateral breast cancer: known genetic carriers, those with strong familial risk but no demonstrable genetic mutation and women who are of young age at presentation. The review supports the role of contralateral prophylactic mastectomy in “high risk” groups where the evidence suggests a reduction in contralateral breast cancer risk. However, this benefit is less evident in women who are just young at presentation or those who have strong family history but no demonstrable genetic mutation. A multidisciplinary and personalized approach to support individuals in a shared-decision making process is recommended.

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