Laxative effects on small intestinal electrical activity of the conscious dog

1978 ◽  
pp. 73-82 ◽  
Author(s):  
W. D. Atchison ◽  
G. J. Klasek ◽  
P. Bass
Keyword(s):  
Electrical Activity ◽  
Conscious Dog ◽  
Laxative Effects ◽  
Small Intestinal ◽  
Intestinal Electrical Activity

Microcomputer analysis and display of canine small intestinal electrical activity

1987 ◽  
Vol 25 (6) ◽  
pp. 672-676 ◽  
Author(s):  
T. G. Barnett ◽  
T. H. Koeze ◽  
M. A. Pilot ◽  
X. Y. Qin
Keyword(s):  
Electrical Activity ◽  
Small Intestinal ◽  
Intestinal Electrical Activity

Electrical activity of small intestinal smooth muscle and its temperature dependence

1975 ◽  
Vol 229 (5) ◽  
pp. 1268-1276 ◽  
Author(s):  
TY El-Sharkawy ◽  
EE Daniel
Keyword(s):  
Smooth Muscle ◽  
Membrane Potential ◽  
Electrical Activity ◽  
Temperature Dependence ◽  
Intestinal Smooth Muscle ◽  
Plateau Phase ◽  
Control Activity ◽  
Electrical Control ◽  
Electrical Control Activity ◽  
Small Intestinal

Some important features of the intracellularly recorded electrical control activity of rabbit jejunal smooth muscle and its temperature dependence are reported in this study. This activity consisted of repetitive 18-mV depolarizations (control potentials (CP) or slow waves), which at 37degreesC lasted 2 s and had a frequency of 18/min and arose from a membrane potential of --55 mV. In some cells periods between CP's exhibited "diastolic" progressive depolarizations (intercontrol-potential depolarization), which may be the trigger of the CP in driving cells. While CP was usually monophasic, some cells persistently exhibited a notch early in the plateau phase. We suggest that CP consists of two components, an "initial depolarization" and a "secondary depolarization," which are usually fused together to give a monophasic potential. Cooling reduced CP frequency and prolonged its duration and caused more cells to show notching. While amplitude and rate of CP initial depolarization had low Q10's, duration and rates of onset and offset of the secondary depolarization had higher Q10's. Thus, the process responsible for secondary depolarization is more sensitive to temperature thant that underlying initial depolarization of the CP.

Depolarization-induced contractile activity of smooth muscle in calcium-free solution

1982 ◽  
Vol 242 (1) ◽  
pp. C36-C40 ◽  
Author(s):  
A. W. Mangel ◽  
D. O. Nelson ◽  
J. L. Rabovsky ◽  
C. L. Prosser ◽  
J. A. Connor
Keyword(s):  
Electrical Activity ◽  
Contractile Activity ◽  
Electrical Potential ◽  
Smooth Muscles ◽  
Vena Cava ◽  
Barium Chloride ◽  
Direct Electrical Stimulation ◽  
Free Solution ◽  
Triggered Release ◽  
Small Intestinal

In calcium-free solution, strips of cat intestinal muscle developed slow, rhythmic electrical potential changes that triggered contractions. Some strips failed to develop spontaneous electrical activity in calcium-free solution but responded with contractions to depolarization by direct electrical stimulation or by treatment with barium chloride, potassium chloride, or acetylcholine. Similar results were obtained with segments of cat stomach, colon, esophagus, bladder, uterus, and vena cava, as well as with rabbit vena cava. In calcium-free saline, rat small intestinal muscle showed fast electrical activity with accompanying development of a tetanuslike contraction. After 60 min in calcium-free solution, cat small intestinal muscle retained 17.7% of its original concentration of calcium. It is concluded that in some smooth muscles, depolarization-triggered release of intracellular calcium does not require an associated influx of calcium.

Electrical Activity of the Small Intestine With Special Reference to the Origin of Rhythmicity

1958 ◽  
Vol 195 (2) ◽  
pp. 505-515 ◽  
Author(s):  
Duncan A. Holaday ◽  
Herbert Volk ◽  
Julian Mandell
Keyword(s):  
Small Intestine ◽  
Electrical Activity ◽  
Action Potentials ◽  
Human Subjects ◽  
Resting Potential ◽  
Frequency Of Occurrence ◽  
Slow Potential ◽  
Contracting Muscle ◽  
Anesthetized Dogs ◽  
Small Intestinal

Unipolar recordings of small intestinal potentials were obtained from chronic dog preparations with exteriorized segments of bowel, from anesthetized dogs, cats and rabbits at laparotomy and from unanesthetized human subjects. Two dominant types of electrical activity were observed and correlated with function. The first type consisted of brief, nonpropagated, spike-like negative potentials which occurred only immediately preceding and during contraction and varied in frequency of occurrence proportionate to intensity of contraction. It is concluded that they represent the action potentials of contracting muscle fibers. The second type of electrical activity consisted of a recurring complex of slow potential changes, the configuration of which varied with the region of intestine and type of preparation. The complex was most stable and most clearly defined in transplanted segments of dog jejunum. The form of the complex was not altered by anesthetics or by sympathomimetic or parasympathomimetic drugs, and was the same during inactivity as during contractions. Initiation of contractions occurred only during the relatively positive phase of the slow complex. It is concluded that the slow complex is a cyclic alteration of the resting potential of the smooth muscle cells of the intestine which originates more or less synchronously in adjacent cells and is associated with a mechanism which renders the muscle alternately relatively excitable and absolutely refractory.

Peptide YY augments postprandial small intestinal absorption in the conscious dog

1994 ◽  
Vol 167 (6) ◽  
pp. 570-574 ◽  
Author(s):  
Anton J. Bilchik ◽  
Oscar Joe Hines ◽  
Michael J. Zinner ◽  
Thomas E. Adrian ◽  
Joshua J. Berger ◽  
...  
Keyword(s):  
Intestinal Absorption ◽  
Peptide Yy ◽  
Conscious Dog ◽  
Small Intestinal ◽  
Small Intestinal Absorption

Computer Analysis of Intestinal Electrical Activity

1978 ◽  
Vol 23 (s1) ◽  
pp. 50-51
Author(s):  
A. Pousse ◽  
C. Mendel ◽  
J. F. Grenier
Keyword(s):  
Electrical Activity ◽  
Computer Analysis ◽  
Intestinal Electrical Activity

scholarly journals Changes in intestinal electrical activity during ischaemia correlate to pathology

2004 ◽  
Vol 22 (1) ◽  
Author(s):  
JK Lapido ◽  
LA Bradshaw ◽  
S Halter ◽  
WO Richards
Keyword(s):  
Electrical Activity ◽  
Intestinal Electrical Activity
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