Isolated Tissues and Organs

2019 ◽  
pp. 19-28
Author(s):  
Jayanta Kumar Patra ◽  
Swagat Kumar Das ◽  
Gitishree Das ◽  
Hrudayanath Thatoi
Keyword(s):  
Isolated Tissues

Structure-activity studies of C- and N-terminal fragments of cholecystokinin 26–33 in guinea pig isolated tissues

Neuropeptides ◽  
1987 ◽  
Vol 10 (1) ◽  
pp. 9-18 ◽  
Author(s):  
P. Gaudreau ◽  
S. St-Pierre ◽  
C.B. Pert ◽  
R. Quirion
Keyword(s):  
Guinea Pig ◽  
Structure Activity ◽  
C And N ◽  
Isolated Tissues

Electrical Phenomena and Isolated Tissues from the Brain

1969 ◽  
pp. 115-136 ◽  
Author(s):  
John A. Harvey ◽  
Henry McIlwain
Keyword(s):  
The Brain ◽  
Isolated Tissues

Vasoconstrictor activity in cerebrospinal fluid from patients subjected to early surgery for ruptured intracranial aneurysms

1981 ◽  
Vol 55 (2) ◽  
pp. 237-245 ◽  
Author(s):  
David J. Boullin ◽  
Lennart Brandt ◽  
Bengt Ljunggren ◽  
Philip Tagari
Keyword(s):  
Cerebrospinal Fluid ◽  
Content Type ◽  
Vasoactive Substances ◽  
Angiographic Vasospasm ◽  
Close Relationship ◽  
Surgical Adjunct ◽  
Serial Samples ◽  
Subarachnoid Blood ◽  
Ruptured Intracranial Aneurysms ◽  
Isolated Tissues

✓ Vasoconstrictor activity was examined in serial samples of cerebrospinal fluid (CSF) obtained from 10 patients undergoing aneurysm clipping within 48 hours after subarachnoid hemorrhage (SAH). There was no close relationship between vasoconstrictor activity in postoperative CSF samples and the patient's clinical condition or angiographic vasospasm. The identity of the vasoconstrictor substance(s) in CSF was not established, but serotonin, histamine, norepinephrine, epinephrine, acetylcholine, or angiotensinII were eliminated as prime vasoconstrictor agents inducing cerebral vasospasm. Differences in the temporal profile of the responses of isolated tissues to CSF from patients with early and late surgery suggested that differing substances were involved in the production of spasm. A correlation between CSF potassium concentrations and vasoactive substances was found, but potassium could not account for vasoconstrictor activity of CSF. A log:linear correlation between total vasoconstrictor activity and total CSF collected could not be explained. Also, because of possible differences in the identity of vasoactive substances in CSF in this study compared to earlier studies, clinical comparisons based on apparent differences in pharmacological potency of CSF were not warranted. Nevertheless, removal of subarachnoid blood by cisternal rinsing seemed to be a useful surgical adjunct.

Hexoprenaline: ?-adrenoreceptor selectivity in isolated tissues from the guinea-pig

1975 ◽  
Vol 2 (6) ◽  
pp. 541-547 ◽  
Author(s):  
Stella R. O'Donnell ◽  
Janet C. Wanstall
Keyword(s):  
Guinea Pig ◽  
Isolated Tissues

Isolated Tissues

2002 ◽  
Author(s):  
Terry Kenakin
Keyword(s):  
Isolated Tissues

Alternative RNA splicing that is spatially regulated: generation of transcripts from the Antennapedia gene of Drosophila melanogaster with different protein-coding regions

1988 ◽  
Vol 8 (10) ◽  
pp. 4143-4154
Author(s):  
V L Stroeher ◽  
J C Gaiser ◽  
R L Garber
Keyword(s):  
Alternative Splicing ◽  
Rna Splicing ◽  
Developmental Stages ◽  
Molecular Evidence ◽  
Rnase Protection ◽  
Protein Coding ◽  
Spatial Regulation ◽  
Coding Regions ◽  
Imaginal Disks ◽  
Isolated Tissues

We have shown previously that transcription of the Drosophila homeotic gene Antennapedia results in four major RNA species which differ in long 5'- and 3'-untranslated sequences. The protein-coding portion of these transcripts, however, is located in exons common to all. Using RNase protection assays and further cDNA clone isolation, we have now detected two alternative splicing events between exons of this region. These result in four RNA variations which, if translated, would encode a family of Antennapedia proteins. By analyzing transcripts from various developmental stages and isolated tissues, we show that alternative splicing is under strict temporal and spatial regulation. For example, while similar patterns of splicing were found for all wild-type thoracic imaginal disks examined, these differed distinctly from the patterns observed in neural tissues. Our results suggest that individual RNAs may be associated with different biological roles, and provide molecular evidence that the Antennapedia gene is involved in multiple functions.

scholarly journals K channel opening effects of YM099 in isolated tissues.

1993 ◽  
Vol 61 ◽  
pp. 255
Author(s):  
Yasuko Shirai ◽  
Kumiko Shibasaki ◽  
Wataru Uchida ◽  
Osamu Inagaki ◽  
Yuzo Matsumoto ◽  
...  
Keyword(s):  
K Channel ◽  
Channel Opening ◽  
Isolated Tissues
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