New data on the synaptic process of Mesocricetus auratus: connecting fibers, telomere association and heterosynapsis

Genetica ◽  
1987 ◽  
Vol 74 (2) ◽  
pp. 105-112 ◽  
Author(s):  
M. Guitart ◽  
M. Pons� ◽  
M. D. Coll ◽  
J. Egozcue
Keyword(s):  
Mesocricetus Auratus ◽  
Synaptic Process ◽  
Telomere Association

scholarly journals Binding and Partial Denaturing of G-quartet DNA by Cdc13p ofSaccharomyces cerevisiae

2001 ◽  
Vol 276 (50) ◽  
pp. 47671-47674 ◽  
Author(s):  
Yi-Chien Lin ◽  
Jing-Wen Shih ◽  
Chia-Ling Hsu ◽  
Jing-Jer Lin
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Intermolecular Association ◽  
Telomere Association ◽  
Dna Quadruplex ◽  
Telomere Replication ◽  
Dna Quadruplexes

The protein Cdc13p binds telomeresin vivoand is essential for the maintenance of the telomeres ofSaccharomyces cerevisiae. In addition, Cdc13p is known to bind single-stranded TG1–3DNAin vitro. Here we have shown that Cdc13p also binds DNA quadruplex, G-quartet, formed by TG1–3DNA. Moreover, the binding of Cdc13p causes a partial denaturing of the G-quartet DNA. Formation of DNA quadruplexes may involve the intermolecular association of TG1–3DNA and inhibit the extension of telomeres by telomerase. Thus, our finding suggests that Cdc13p may disrupt telomere association and facilitate telomere replication.

scholarly journals Topical treatment of experimental cutaneous leishmaniasis in golden hamster (Mesocricetus auratus) with formulations containing pentamidine

2017 ◽  
Vol 47 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Claudia Dantas COMANDOLLI-WYREPKOWSKI ◽  
Iryna GRAFOVA ◽  
Maricleide de Farias NAIFF ◽  
Maurizio AVELLA ◽  
Gennaro GENTILE ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Topical Treatment ◽  
Usnic Acid ◽  
Parasite Burden ◽  
Experimental Treatment ◽  
Mesocricetus Auratus ◽  
Current Treatment ◽  
Tissue Samples ◽  
Golden Hamsters ◽  
Pentamidine Isethionate

ABSTRACT Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration. The aim of this work was to evaluate the topical formulations containing pentamidine isethionate (PI) in the experimental treatment of cutaneous leishmaniasis (CL). Golden hamsters (Mesocricetus auratus) were infected in the nose with Leishmania (Leishmania) amazonensis. Six treatment groups received different topical treatments of anhydrous or hydrating emulsions, for a maximum of 10 days, with an application of 50 mg day-1. After treatment tissue samples of lesions were evaluated by histology, transmission electron microscopy and biopsy cultivation. Compared with untreated group, topical treatment with hydrating emulsion with 10% PI and usnic acid (ACE5AU) showed significantly decrease in volume lesion (P= 0.028) on 20th day after the end of the treatment with reduction of 27.37%. Topical treatment with anhydrous emulsion with 10% PI and usnic acid (ACPU) reduces parasite burden in Golden hamsters. This study demonstrated the potential of topical treatment to reduce the number of parasites that could be combined with others drugs and to have a faster and more effective treatment of cutaneous leishmaniasis.

scholarly journals Immunomodulatory treatment with thalidomide in experimental leptospirosis in Golden Syrian hamsters (Mesocricetus auratus)

2013 ◽  
Vol 108 (2) ◽  
pp. 105-111 ◽  
Author(s):  
L. M. Soares ◽  
J. O. Macedo ◽  
E. C. de Azevedo ◽  
C. S. Santos ◽  
M. d. Q. Sampaio ◽  
...  
Keyword(s):  
Mesocricetus Auratus ◽  
Immunomodulatory Treatment ◽  
Syrian Hamsters

Pineal melatonin in hibernating and aroused golden hamsters (Mesocricetus auratus)

1984 ◽  
Vol 77 (4) ◽  
pp. 759-762 ◽  
Author(s):  
Jiří Vaněček ◽  
Ladislav Janský ◽  
Helena Illnerová ◽  
Klaus Hoffmann
Keyword(s):  
Mesocricetus Auratus ◽  
Pineal Melatonin ◽  
Golden Hamsters

Effect of the interintromission interval on lordotic response and attack latency in golden hamsters (Mesocricetus auratus).

1988 ◽  
Vol 102 (4) ◽  
pp. 388-391 ◽  
Author(s):  
U. William Huck ◽  
Robert D. Lisk ◽  
Eric J. Parente
Keyword(s):  
Mesocricetus Auratus ◽  
Golden Hamsters ◽  
Attack Latency

Population Control in Confined Colonies of Golden Hamsters (Mesocricetus auratus Waterhouse)

2010 ◽  
Vol 37 (3) ◽  
pp. 225-236 ◽  
Author(s):  
L. Goldman ◽  
Heidi Swanson
Keyword(s):  
Population Control ◽  
Mesocricetus Auratus ◽  
Golden Hamsters
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