Development and ageing of the articular cartilage of the rabbit knee joint: distribution of the fibrillar collagens

1996 ◽  
Vol 194 (6) ◽  
Author(s):  
YvetteS. Bland ◽  
DoreenE. Ashhurst
Keyword(s):  
Articular Cartilage ◽  
Knee Joint ◽  
Joint Distribution ◽  
Rabbit Knee ◽  
Fibrillar Collagens

Site-specific cell-tissue interactions in rabbit knee joint articular cartilage

2016 ◽  
Vol 49 (13) ◽  
pp. 2882-2890 ◽  
Author(s):  
A.P. Ronkainen ◽  
J.M. Fick ◽  
W. Herzog ◽  
R.K. Korhonen
Keyword(s):  
Articular Cartilage ◽  
Knee Joint ◽  
Specific Cell ◽  
Site Specific ◽  
Rabbit Knee ◽  
Tissue Interactions ◽  
Cell Tissue

scholarly journals The Effects of Bupivacaine and Neostigmine on Articular Cartilage and Synovium in the Rabbit Knee Joint

2004 ◽  
Vol 32 (5) ◽  
pp. 513-519 ◽  
Author(s):  
N Dogan ◽  
AF Erdem ◽  
Z Erman ◽  
M Kizilkaya
Keyword(s):  
Articular Cartilage ◽  
Knee Joint ◽  
Rabbit Knee

The effects of ketorolac and morphine on articular cartilage and synovium in the rabbit knee joint

2004 ◽  
Vol 82 (7) ◽  
pp. 502-505 ◽  
Author(s):  
Nazim Dogan ◽  
Ali Fuat Erdem ◽  
Cemal Gundogdu ◽  
Husnu Kursad ◽  
Mehmet Kizilkaya
Keyword(s):  
Articular Cartilage ◽  
Knee Joint ◽  
Synovial Membrane ◽  
Inflammatory Cell ◽  
Inflammatory Cell Infiltration ◽  
Knee Joints ◽  
Cell Infiltration ◽  
Histopathological Changes ◽  
Rabbit Knee ◽  
Group I

Analgesics are commonly injected intra-articularly for analgesia after arthroscopic surgery, especially of knee joints. The aim of this study was to research the effects of ketorolac and morphine on articular cartilage and synovial membrane. This study used rabbit right and left hind knee joints. The treatments, saline, morphine, or ketorolac, were administered intra-articularly 24 h after injection, and 5 joints from animals in each drug group were chosen randomly to form Group I and subgroups of Group I. The same procedures were applied after 48 h and 10 days of injection to form Groups II and III, respectively, and subgroups of these groups. Knee joints were excised and a blinded observer evaluated the histopathology according to inflammation of the articular cartilage, inflammatory cell infiltration, hypertrophy, and hyperplasia of the synovial membrane. No histopathological changes were found in the control groups. In the ketorolac and morphine groups, there were varying degrees of synovial membrane inflammatory cell infiltration and minimal, mild, or moderate synovial membrane cell hyperplasia or hypertrophy. Except for the ketorolac group at 24 h, both ketorolac and morphine groups showed more histopathological changes than controls (p < 0.05). Morphine and ketorolac both cause mild histopathological changes in rabbit knee joints, morphine causing more than ketorolac, but both of the drugs can be used intra-articularly with safety.Key words: intra-articular analgesia, knee joint, histopathological changes, articular cartilage, synovial membrane.

Effects of Osmium Tetroxide on the Rabbit Knee Joint Normal Synovial Membrane

1987 ◽  
Vol 16 (1) ◽  
pp. 121-129
Author(s):  
M. Möttönen ◽  
M. Pantio ◽  
T. Nevalainen
Keyword(s):  
Knee Joint ◽  
Synovial Membrane ◽  
Osmium Tetroxide ◽  
Rabbit Knee
Sign in / Sign up

Export Citation Format

Share Document