Ferric reductases or flavin reductases?

BioMetals ◽  
1994 ◽  
Vol 7 (1) ◽  
Author(s):  
Marc Fontecave ◽  
Jacques Cov�s ◽  
Jean-Louis Pierre
Keyword(s):  
Ferric Reductases

scholarly journals Candida albicans Ferric Reductases Are Differentially Regulated in Response to Distinct Forms of Iron Limitation by the Rim101 and CBF Transcription Factors

2008 ◽  
Vol 7 (7) ◽  
pp. 1168-1179 ◽  
Author(s):  
Yong-Un Baek ◽  
Mingchun Li ◽  
Dana A. Davis
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Candida Albicans ◽  
Transcription Factors ◽  
Iron Acquisition ◽  
Mammalian Host ◽  
Regulatory Sequence ◽  
Ferric Reductase ◽  
Reductase Gene ◽  
Ferric Reductases

ABSTRACT Iron is an essential nutrient that is severely limited in the mammalian host. Candida albicans encodes a family of 15 putative ferric reductases, which are required for iron acquisition and utilization. Despite the central role of ferric reductases in iron acquisition and mobilization, relatively little is known about the regulatory networks that govern ferric reductase gene expression in C. albicans. Here we have demonstrated the differential regulation of two ferric reductases, FRE2 and FRP1, in response to distinct iron-limited environments. FRE2 and FRP1 are both induced in alkaline-pH environments directly by the Rim101 transcription factor. However, FRP1 but not FRE2 is also induced by iron chelation. We have identified a CCAAT motif as the critical regulatory sequence for chelator-mediated induction and have found that the CCAAT binding factor (CBF) is essential for FRP1 expression in iron-limited environments. We found that a hap5Δ/hap5Δ mutant, which disrupts the core DNA binding activity of CBF, is unable to grow under iron-limited conditions. C. albicans encodes three CBF-dependent transcription factors, and we identified the Hap43 protein as the CBF-dependent transcription factor required for iron-limited responses. These studies provide key insights into the regulation of ferric reductase gene expression in the fungal pathogen C. albicans.

Iron uptake mechanisms in plants: Functions of the FRO family of ferric reductases

Plant Science ◽  
2009 ◽  
Vol 176 (6) ◽  
pp. 709-714 ◽  
Author(s):  
Jeeyon Jeong ◽  
Erin L. Connolly
Keyword(s):  
Iron Uptake ◽  
Uptake Mechanisms ◽  
Ferric Reductases

Ferric reductases of Legionella pneumophila

BioMetals ◽  
1993 ◽  
Vol 6 (2) ◽  
Author(s):  
MarkT. Poch ◽  
W. Johnson
Keyword(s):  
Legionella Pneumophila ◽  
Ferric Reductases

scholarly journals The Fungal Pathogen Candida glabrata Does Not Depend on Surface Ferric Reductases for Iron Acquisition

2017 ◽  
Vol 8 ◽  
Author(s):  
Franziska Gerwien ◽  
Abu Safyan ◽  
Stephanie Wisgott ◽  
Sascha Brunke ◽  
Lydia Kasper ◽  
...  
Keyword(s):  
Fungal Pathogen ◽  
Candida Glabrata ◽  
Iron Acquisition ◽  
Ferric Reductases

Ferric Reductases in Escherichia coli: The Contribution of the Hemoglobin-like Protein

1994 ◽  
Vol 198 (1) ◽  
pp. 127-131 ◽  
Author(s):  
M. Eschenbrenner ◽  
J. Coves ◽  
M. Fontecave
Keyword(s):  
Escherichia Coli ◽  
Ferric Reductases

scholarly journals Dissimilatory iron reduction in Escherichia coli: identification of CymA of Shewanella oneidensis and NapC of E. coli as ferric reductases

2008 ◽  
Vol 68 (3) ◽  
pp. 706-719 ◽  
Author(s):  
Johannes S. Gescher ◽  
Carmen D. Cordova ◽  
Alfred M. Spormann
Keyword(s):  
Escherichia Coli ◽  
Iron Reduction ◽  
Shewanella Oneidensis ◽  
E Coli ◽  
Dissimilatory Iron Reduction ◽  
Ferric Reductases

scholarly journals Free flavins accelerate release of ferrous iron from iron storage proteins by both free flavin-dependent and -independent ferric reductases in Escherichia coli

2019 ◽  
Vol 65 (6) ◽  
pp. 308-315
Author(s):  
Junichi Satoh ◽  
Shinya Kimata ◽  
Shota Nakamoto ◽  
Tatsuya Ishii ◽  
Eisuke Tanaka ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Ferrous Iron ◽  
Storage Proteins ◽  
Iron Storage ◽  
Iron Storage Proteins ◽  
Ferric Reductases

Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases

2003 ◽  
Vol 1651 (1-2) ◽  
pp. 116-123 ◽  
Author(s):  
J.D. Vargas ◽  
B. Herpers ◽  
A.T. McKie ◽  
S. Gledhill ◽  
J. McDonnell ◽  
...  
Keyword(s):  
Stromal Cell ◽  
Cytochrome B561 ◽  
Ferric Reductases

Ferric Reductases CG1275 and Nemy in Iron Uptake in Drosophila S2 cells

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Keyata Lewis ◽  
Jessica Holst ◽  
Gregory Kane ◽  
Mirella Castaneda ◽  
Maureen J. Gorman ◽  
...  
Keyword(s):  
Iron Uptake ◽  
S2 Cells ◽  
Drosophila S2 Cells ◽  
Ferric Reductases
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