The cytotoxicity of T-2 toxin and related 12,13-epoxytrichothecenes to Adriamycin-sensitive and-resistant P388 leukemia cells

1989 ◽  
Vol 24 (4) ◽  
Author(s):  
Avner Ramu ◽  
Boris Yagen ◽  
Nili Ramu
Keyword(s):  
Leukemia Cells ◽  
P388 Leukemia

Comparison of uptake of mitomycin C and KW-2149 by murine P388 leukemia cells sensitive or resistant to mitomycin C

1993 ◽  
Vol 32 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Eiji Kobayashi ◽  
Masami Okabe ◽  
Motomichi Kono ◽  
Hitoshi Arai ◽  
Masaji Kasai ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Leukemia Cells ◽  
P388 Leukemia

Polyamine Metabolism in P388 Leukemia Cells and in Ascites Tumor-Bearing Mice

Pathobiology ◽  
1984 ◽  
Vol 52 (5) ◽  
pp. 279-285 ◽  
Author(s):  
T. Kremmer ◽  
L. Selmeci ◽  
Susan Bardócz ◽  
L. Holczinger ◽  
Susan Bálint
Keyword(s):  
Leukemia Cells ◽  
Polyamine Metabolism ◽  
Ascites Tumor ◽  
P388 Leukemia ◽  
Tumor Bearing

Gamma interferon administration differently affects sensitive or doxorubicin resistant P388 leukemia cells; a relationship with antioxidant defenses?

1989 ◽  
Vol 21 ◽  
pp. 21-22 ◽  
Author(s):  
M.G. Armata ◽  
M. Crescimanno ◽  
H. Tapiero ◽  
L. Rausa ◽  
N. D'Alessandro
Keyword(s):  
Gamma Interferon ◽  
Antioxidant Defenses ◽  
Leukemia Cells ◽  
P388 Leukemia

scholarly journals Oxidation and Acetylation of Ursolic and Oleanolic Acids Isolated from Fragraea fragrans fruits; Antiproliferation of P388 Leukemia Cells

2014 ◽  
Vol 14 (3) ◽  
pp. 269-276 ◽  
Author(s):  
Dasril Basir ◽  
Julinar Julinar ◽  
Eva Agustriana ◽  
Budi Untari
Keyword(s):  
Cell Growth ◽  
Natural Product ◽  
Ursolic Acid ◽  
Oleanolic Acid ◽  
Leukemia Cell ◽  
Leukemia Cells ◽  
P388 Leukemia ◽  
Continuous Work ◽  
Cell Proliferations ◽  
Product Chemistry

An interesting natural product chemistry aspect of Fragraea fragrans is that their fruits are richness with ursolic acid and its isomer oleanolic acid (3.05% of dried powder). As our continuous work on these inseparable structural isomeric triterpenes, this paper reports that 51.0% of inseparable 3-oxo-ursolic[3-oxo-oleanolic] acids and 48.6% of inseparable 3-acethyl-ursolic [3-acethyl-oleanolic] acids have already been made from those triterpenes as starting materials of the oxidized and acetylated compounds and evaluated their activity against P388 leukemia cells. The activity of 3-oxo-ursolic [3-oxo-oleanolic] acids with IC50 = 18.6 µg/mL exhibited three-fold more potent against P388 leukemia cell proliferations compared to ursolic [oleanolic] acids with IC50 = 53.5 µg/mL; while the 3-acethyl-ursolic [3-acethyl-oleanolic] acids with IC50 = 37.9 µg/mL showed two-fold more potent then their parent triterpenes (IC50 = 53.5 µg/mL) in the inhibition of P388 leukemia cell growth.

Changes in the Polyamine and Nucleotide Metabolism of P388 Leukemia Cells Treated with DL-α-Difluoromethylornithine in Culture

Pathobiology ◽  
1988 ◽  
Vol 56 (3) ◽  
pp. 131-137 ◽  
Author(s):  
T. Kremmer ◽  
I. Pályi ◽  
L. Holczinger ◽  
I. Lörincz ◽  
M. Boldizsár ◽  
...  
Keyword(s):  
Nucleotide Metabolism ◽  
Leukemia Cells ◽  
P388 Leukemia

Formation, resealing and persistence of DNA breaks produced by 4-demethoxydaunorubicin in P388 leukemia cells

1989 ◽  
Vol 72 (1-2) ◽  
pp. 113-123 ◽  
Author(s):  
Giovanni Capranico ◽  
Stella Tinelli ◽  
Franco Zunino
Keyword(s):  
Leukemia Cells ◽  
Dna Breaks ◽  
P388 Leukemia ◽  
Persistence Of Dna

Induction of functional Fc receptors in P388 leukemia cells

1985 ◽  
Vol 157 (2) ◽  
pp. 511-519 ◽  
Author(s):  
Donald A. Cohen ◽  
N.Lynn Stotelmyer ◽  
Alan M. Kaplan
Keyword(s):  
Fc Receptors ◽  
Leukemia Cells ◽  
P388 Leukemia

scholarly journals Antitumor Activity and Cellular Accumulation of a New Platinum Complex, (-)-(R)-2-Aminomethylpyrrolidine(1,l-cyclobutanedicarboxylato)platinum(II) Monohydrate, in Cisplatin-sensitive and -resistant Murine P388 Leukemia Cells

1992 ◽  
Vol 83 (3) ◽  
pp. 304-311 ◽  
Author(s):  
Keiichi Kamisango ◽  
Tomoko Matsumoto ◽  
Ken-ichi Akamatsu ◽  
Kazumi Morikawa ◽  
Tazuko Tashiro ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Platinum Complex ◽  
Leukemia Cells ◽  
Cellular Accumulation ◽  
P388 Leukemia
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