The fine structure of the megakaryocyte of the bone marrow of the guinea pig

1964 ◽  
Vol 64 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Peter P. H. Bruyn
Keyword(s):  
Bone Marrow ◽  
Fine Structure ◽  
Guinea Pig

Glycogen in guinea pig neutrophils: Ultrastructural study of neutrophils at the intradermal site of BCG injection

1983 ◽  
Vol 41 ◽  
pp. 726-727
Author(s):  
Corazon D. Bucana
Keyword(s):  
Bone Marrow ◽  
Guinea Pig ◽  
Electron Density ◽  
Peritoneal Cavity ◽  
Ultrastructural Study ◽  
Guinea Pigs ◽  
Random Distribution ◽  
Glycogen Content ◽  
Polymorphonuclear Neutrophils ◽  
Ultrastructural Studies

In the circulating blood of man and guinea pigs, glycogen occurs primarily in polymorphonuclear neutrophils and platelets. The amount of glycogen in neutrophils increases with time after the cells leave the bone marrow, and the distribution of glycogen in neutrophils changes from an apparently random distribution to large clumps when these cells move out of the circulation to the site of inflammation in the peritoneal cavity. The objective of this study was to further investigate changes in glycogen content and distribution in neutrophils. I chose an intradermal site because it allows study of neutrophils at various stages of extravasation.Initially, osmium ferrocyanide and osmium ferricyanide were used to fix glycogen in the neutrophils for ultrastructural studies. My findings confirmed previous reports that showed that glycogen is well preserved by both these fixatives and that osmium ferricyanide protects glycogen from solubilization by uranyl acetate.I found that osmium ferrocyanide similarly protected glycogen. My studies showed, however, that the electron density of mitochondria and other cytoplasmic organelles was lower in samples fixed with osmium ferrocyanide than in samples fixed with osmium ferricyanide.

Fine Structure of Guinea Pig Vestibular Kinocilium

1989 ◽  
Vol 108 (1-2) ◽  
pp. 26-30 ◽  
Author(s):  
Toshihiko Kikuchi ◽  
Tomonori Takasaka ◽  
Akira Tonosaki ◽  
Hiroshi Watanabe
Keyword(s):  
Fine Structure ◽  
Guinea Pig

Fine Structure of the Guinea-Pig Macula Utriculi A Preliminary Report

1954 ◽  
Vol 43 (sup116) ◽  
pp. 298-303 ◽  
Author(s):  
Jan Wersäll ◽  
Hans Engström ◽  
Sture Hjorth
Keyword(s):  
Fine Structure ◽  
Guinea Pig ◽  
Preliminary Report

scholarly journals THE RESPONSE OF EOSINOPHILS IN THE GUINEA PIG TO SENSITIZATION, ANAPHYLAXIS AND VARIOUS DRUGS

Blood ◽  
1949 ◽  
Vol 4 (3) ◽  
pp. 217-246 ◽  
Author(s):  
MAX SAMTER
Keyword(s):  
Bone Marrow ◽  
Guinea Pig ◽  
Eosinophil Count ◽  
Guinea Pigs ◽  
Specific Antigen ◽  
Wide Range ◽  
The Individual ◽  
Bone Marrow Blood ◽  
Antihistamine Drugs ◽  
Definite Correlation

Abstract 1. The eosinophilic response of the guinea pig sensitized and reinjected with the specific antigen varies with the nature of the antigen used, but also with the individual guinea pig in any groupsensitized and reinjected with the same antigen. 2. Certain antihistamine drugs which abolish anaphylactic symptoms, do not abolish the eosinophilic response. 3. The severity of anaphylactic "shock" symptoms has no influence on the eosinophilic response. 4. Histamine phosphate has no effect on the eosinophil count of nonsensitized guinea pigs protected by benadryl; it causes a distinct eosinophilic response in sensitized animals. 5. Heparin—in the dose injected—produced only an insignificant rise in the peripheral eosinophil count of sensitized guinea pigs; adenosine had no effect. 6. Attempts were made to correlate the eosinophilic response in bone marrow, blood and shock tissue of guinea pigs sensitized and reinjected with a specific antigen. The variation within a wide range of the number of eosinophils in the bone marrow of nonsensitized and of sensitized, reinjected guinea pigs is emphasized. A definite correlation seems to exist between the presence of a large number of eosinophils in blood and lungs; it is shown, however, that this observation permits only limited conclusions. 7. The factors which account for discrepancies in the interpretation of the eosinophilic response, e.g., nature of antigen, route of administration and characteristics of species, are analyzed. 8. The significance of the findings is reviewed in the light of previous work.

A novel bioaction of PAF: Induction of microbicidal activity in guinea pig bone marrow cells

Lipids ◽  
1988 ◽  
Vol 23 (12) ◽  
pp. 1119-1124 ◽  
Author(s):  
Hidetoshi Hayashi ◽  
Ichiro Kudo ◽  
Toshiyuki Kato ◽  
Ryushi Nozawa ◽  
Shoshichi Nojima ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Guinea Pig ◽  
Bone Marrow Cells ◽  
Microbicidal Activity ◽  
Marrow Cells
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