Self-stimulation of the brain by cats: Technique and preliminary drug-effects

1962 ◽  
Vol 3 (6) ◽  
pp. 449-454 ◽  
Author(s):  
Zola P. Horovitz ◽  
May-I. Chow ◽  
Peter L. Carlton
1966 ◽  
Vol 19 (1) ◽  
pp. 79-82 ◽  
Author(s):  
B. P. H. Poschel ◽  
F. W. Ninteman

Rats with electrodes in the posterior lateral hypothalamus were trained in a chamber having two platforms. When standing on one platform, S received rewarding brain stimulation continuously. Switching to the other platform turned stimulation off. The proportion of time spent on the positive platform indicated the reward value of stimulation. Preliminary tests determined that the time measure was positively related to stimulation intensity. Drug tests determined that tranylcypromine and methamphetamine greatly increased the reward value of weak stimulation, while chlorpromazine greatly decreased the reward value of strong stimulation. Since Ss were not required to work for brain stimulation, these effects on reward value were shown not to be mere artifacts of the drugs' effects on motor output.


1963 ◽  
Vol 120 (6) ◽  
pp. 571-577 ◽  
Author(s):  
ROBERT G. HEATH

1962 ◽  
Vol 203 (2) ◽  
pp. 371-373 ◽  
Author(s):  
Paul Stark ◽  
Giovanni Fazio ◽  
Eugene S. Boyd

Intracranial self-stimulation experiments in the dog using a two-wire electrode, with each wire used as a monopolar electrode and the combination as a bipolar electrode, show that monopolar stimulation may produce either a higher or a lower rate of response than that produced by bipolar stimulation. A theoretical consideration of the changes in current density around the electrode when it is changed from a monopolar to a bipolar electrode shows that such differences are to be expected. The exact location of the structure being stimulated with reference to the two electrode tips will determine whether the structure is subjected to a higher current density on monopolar or on bipolar stimulation.


1968 ◽  
Vol 65 (2) ◽  
pp. 261-264 ◽  
Author(s):  
James Macdougall ◽  
William Bevan

1962 ◽  
Vol 3 (6) ◽  
pp. 455-462 ◽  
Author(s):  
Zola P. Horovitz ◽  
May-I. Chow ◽  
Peter L. Carlton

1976 ◽  
Vol 17 (2) ◽  
pp. 353-355
Author(s):  
J OVERDIJK ◽  
N VANDEPOLL ◽  
H VANDIS

Science ◽  
1963 ◽  
Vol 141 (3583) ◽  
pp. 823-824 ◽  
Author(s):  
S. S. Pliskoff ◽  
T. D. Hawkins

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