Enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: Relevance to the mechanism of the antidepressive effect of electroconvulsive therapy

1979 ◽  
Vol 61 (2) ◽  
pp. 167-170 ◽  
Author(s):  
D. W. Costain ◽  
A. R. Green ◽  
D. G. Grahame-Smith
2011 ◽  
Vol 26 (S2) ◽  
pp. 1723-1723
Author(s):  
A. Goshiri ◽  
M.R. Mokhtari ◽  
P. Aghamohammad Hassani ◽  
A. Sayyadi

BackgroundElectroconvulsive therapy (ECT) is widely and effectively used to treat psychiatric disorders. When electrodes are placed on both sides of the head on temporal bones it is unclear whether ECT affect on hearing system because hearing system situated in temporal lobe. Whereas these electrodes are placed on temporal bone and hearing system in TEMPORAL LOBE this study was designed.MethodsWe studied the effects of electroconvulsive shock on hearing system. Audiometric tests were performed in 15 adult patients with major depression under treatment with ECT before and 24 h after ECT.ResultsHearing was decreased at 24 hours after ECT about 5 db. Right ear was affected more and the most changes were observed at 8000 khz.ConclusionsIt appears that electroconvulsive shock has early effects on hearing system. Further studies should be performed with more cases and Delayed effects should be investigated.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1210-1210
Author(s):  
A. Golshiri ◽  
P. Aghamohammad Hassani ◽  
A. Sayyadi ◽  
M. Mokhtari

BackgroundElectroconvulsive therapy (ECT) is widely and effectively used to treat psychiatric disorders. When electrodes are placed on both sides of the head on temporal bones it is unclear whether ECT affect on hearing system because hearing system situated in temporal lobe. Whereas these electrodes are placed on temporal bone and hearing system in TEMPORAL LOBE this study was designed.MethodsWe studied the effects of electroconvulsive shock on hearing system. Audiometric tests were performed in 15 adult patients with major depression under treatment with ECT before and 24h after ECT.ResultsHearing was decreased at 24 hours after ECT about 5 db. Right ear was affected more and the most changes were observed at 8000 khz.ConclusionsIt appears that electroconvulsive shock has early effects on hearing system. Further studies should be performed with more cases and Delayed effects should be investigated.


1976 ◽  
Vol 21 (2) ◽  
pp. 61-67 ◽  
Author(s):  
C. G. Costello

Recent reports in the lay literature and professional house publications both have brought into question the validity of electroconvulsive shock as a therapy, and highlighted the iatrogenic effects of the treatment. The failure to complete a study of the therapeutic effectiveness of ECT is reported. The study incorporated two conditions thought to be essential for an adequate evaluation of the treatment: a placebo-ECT group; and double-blind procedures. The failure of the study revealed the difficulty of conducting to completion an adequately controlled investigation of a treatment already accepted by clinicians. Other placebo-controlled double-blind studies are reviewed, and alternative study designs are discussed.


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