Plasma polymerization of ethane. I. Experimental studies of effluent gas composition and polymer deposition rates

1983 ◽  
Vol 3 (2) ◽  
pp. 139-161 ◽  
Author(s):  
R. J. Jensen ◽  
A. T. Bell ◽  
D. S. Soong
Keyword(s):  
Plasma Polymerization ◽  
Experimental Studies ◽  
Gas Composition ◽  
Deposition Rates ◽  
Polymer Deposition

Plasma polymerization of ethane. II. Theoretical analysis of effluent gas composition and polymer deposition rates

1983 ◽  
Vol 3 (2) ◽  
pp. 163-192 ◽  
Author(s):  
R. J. Jensen ◽  
A. T. Bell ◽  
D. S. Soong
Keyword(s):  
Theoretical Analysis ◽  
Plasma Polymerization ◽  
Gas Composition ◽  
Deposition Rates ◽  
Polymer Deposition

Distribution of polymer deposition in plasma polymerization. II. Effect of reactor design

1978 ◽  
Vol 16 (2) ◽  
pp. 313-326 ◽  
Author(s):  
H. Yasuda ◽  
Toshihiro Hirotsu
Keyword(s):  
Plasma Polymerization ◽  
Reactor Design ◽  
Polymer Deposition

Use of a hypoxic lung as a deoxygenator to provide extended assessment of pulmonary function in rats

1996 ◽  
Vol 80 (5) ◽  
pp. 1835-1840 ◽  
Author(s):  
K. N. DeCampos ◽  
S. H. Keshavjee ◽  
L. Tremblay ◽  
T. Yamashiro ◽  
A. S. Slutsky
Keyword(s):  
Gas Exchange ◽  
Pulmonary Function ◽  
Venous Blood ◽  
Experimental Studies ◽  
Left Lung ◽  
Blood Gases ◽  
Gas Composition ◽  
Host Animal ◽  
The Stability ◽  
Exchange Function

Isolated perfused lung systems are commonly used to assess lung function in experimental studies. Assessment of hemodynamics and gas-exchange function in these systems is limited by the availability of venous blood. This study describes and validates a rat lung perfusion circuit in which a double-lung block ventilated with a hypoxic gas mixture [inspired O2 fraction (FIO2) 0.04; inspired CO2 fraction 0.08; deoxygenator (Deoxy) block] is used to provide blood with blood gases that are similar to mixed venous values to perfuse a study lung (FIO2 0.21; left lung only). This allows extended assessment of hemodynamics and gas exchange. Fifty adult male Wistar rats (300-400 g) were used as double-lung donors. Twenty-five perfusions (of both Deoxy and study lungs) were performed in four protocols (groups 1-5; n = 5). In protocol 1 (group 1), we tested whether exposure to room air affects the gas composition of the blood in the system. We found that the gas composition of the venous reservoir blood was identical to that of the blood entering the study block. In protocol 2, the effect of perfusion time and perfusion flow rate on the stability of the system was assessed. Lungs were perfused at 4 and 12 ml/min (groups 2 and 3, respectively), and the procedure was discontinued if edema or a marked decline in hemodynamics or gas-exchange function was observed. Pulmonary function was excellent and remained stable for 3 (at 12 ml/min) and 5 h (at 4 ml/min). In protocol 3, we examined whether hypoxic ventilation in the Deoxy lungs affects the stability of the system. Despite the low FIO2 used in the Deoxy lungs, the mean pulmonary arterial pressure-to-blood flow relationships in the study and Deoxy lungs were similar. Finally, in protocol 4, perfusion of a damaged study lung did not impair the function of the system. We conclude that this model permits reliable assessment of pulmonary function in rats under controlled ventilation and perfusion conditions. The use of a Deoxy double-lung block simplifies the perfusion apparatus and eliminates the main cause of instability of other systems that use an anesthetized host animal to provide venous blood.

Effect of Lung Airway Branching Pattern and Gas Composition on Particle Deposition. II. Experimental Studies in Human and Canine Lungs

1988 ◽  
Vol 14 (3) ◽  
pp. 321-348 ◽  
Author(s):  
Julie L. Esch ◽  
Dalia M. Spektor ◽  
Morton Lippmann
Keyword(s):  
Particle Deposition ◽  
Experimental Studies ◽  
Branching Pattern ◽  
Gas Composition ◽  
Airway Branching

Plasma Polymerized Thin-Films for Biosensors

2008 ◽  
Vol 47-50 ◽  
pp. 1367-1370
Author(s):  
Chin Chuan Chang ◽  
Shu Ling Wang ◽  
Wen Chi Tseng ◽  
Meng Jiy Wang
Keyword(s):  
Thin Film ◽  
Thin Films ◽  
Chinese Hamster Ovary ◽  
Plasma Polymerization ◽  
Chinese Hamster ◽  
Glass Slide ◽  
Good Adhesion ◽  
Deposition Rates ◽  
Chemical Structures ◽  
Amine Groups

Plasma polymerization is an effective method to directly deposit ultra-thin film on substrates with advantageous properties such as good adhesion and biocompatibility. In this paper, the monomers containing amine groups with various unsaturated structures (propylamine, allylamine) are chosen to provide amine functionalities and to promote biocompatibilities for the polymerized thin films. The deposition rates revealed by measuring the thickness of thin films are characterized by profilometer under various plasma conditions. FTIR and AFM are used to study the chemical structures and morphology of the deposited thin films. In order to examine the applicability of the deposited polymers for biosensors, the activities of the incorporated biomolecules on deposited thin films are analyzed. Chinese hamster ovary (CHO) cells are cultivated on the polymerized thin films. Both propylamine and allylamine polymerized thin films show enhanced cell viability than on glass slide substrates.

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