Circulation to the brain of the rat during acute and prolonged respiratory changes in the acid-base balance

1973 ◽  
Vol 338 (4) ◽  
pp. 347-359 ◽  
Author(s):  
J. L. Pannier ◽  
I. Leusen
1982 ◽  
Vol 63 (1) ◽  
pp. 56-56
Author(s):  
E. S. Karashurov ◽  
S. E. Karashurov

Frequent complications of glomectomy are headaches and a mild, less-like state for several days or weeks after surgery, and sometimes hemi- and monoparesis. The reasons for these complications have not yet been revealed. In search of their explanation, we decided to study the volumetric blood flow of the brain and the acid-base state (ACS). Volumetric blood flow was studied by rheoencephalography (REG) in 43 patients, and acid base balance - in 100 patients (age from 22 to 67 years). The course of bronchial asthma before the operation in the examined patients was moderate and severe.


1962 ◽  
Vol 202 (2) ◽  
pp. 217-220 ◽  
Author(s):  
B. R. Fink ◽  
R. Katz ◽  
H. Reinhold ◽  
A. Schoolman

The ventilation and blood acid-base balance of 19 cats were studied after supracollicular ablation of the forebrain and again after intercollicular transection of the brain stem. The first ablation caused a marked increase in the frequency of respiration, apparently unmasking a caudad facilitory influence through the removal of forebrain inhibition. Hypocapnic apnea could not be induced in this preparation. After intercollicular section there was a sudden fall in frequency, the ventilatory response to CO2 was diminished and hypocapnic apnea was easily induced. It is concluded that a tonic facilitory effect on respiration originates in the rostral midbrain and adjacent diencephalon, possibly in the reticular activating system.


1972 ◽  
Vol 36 (5) ◽  
pp. 625-633 ◽  
Author(s):  
Markku Kaste ◽  
Henry Troupp

✓ Changes in the blood pressure, cerebral sinus pressure, cerebral venous oxygen tension, acid-base balance, respiratory frequency, and respiratory minute volume were studied in the rabbit after a lethal cold injury to the brain. About half of the animals responded to the injury with a quick rise in cerebral sinus pressure and in its relation to blood pressure (CSP/BP); in the other half, cerebral sinus pressure and the CSP/BP ratio rose more slowly. Changes in the CSP/BP ratio correlated well with criteria for changes in respiratory performance. The changes in cerebral venous oxygen tension were reasonably uniform: a dip during freezing, an overshoot to a mean of 1.6 times the original level (about 30 mm Hg) immediately after injury, a gradual return to the pretraumatic level, and then a drop to lower levels. The brain injury led to a respiratory alkalosis that became more pronounced the longer the animals lived. Considered with CSP/BP ratio, respiratory reaction to the brain injury may provide an early and accurate prognosis. The fact that at the time of death the cerebral perfusion pressure was still within a range believed safe for the brain shows that an actual brain injury, in addition to raised intracranial pressure, is important in such experiments and emphasizes the inappropriateness of comparing levels of intracranial pressure raised by a variety of methods.


2014 ◽  
Vol 84 (3-4) ◽  
pp. 0206-0217 ◽  
Author(s):  
Seyedeh-Elaheh Shariati-Bafghi ◽  
Elaheh Nosrat-Mirshekarlou ◽  
Mohsen Karamati ◽  
Bahram Rashidkhani

Findings of studies on the link between dietary acid-base balance and bone mass are relatively mixed. We examined the association between dietary acid-base balance and bone mineral density (BMD) in a sample of Iranian women, hypothesizing that a higher dietary acidity would be inversely associated with BMD, even when dietary calcium intake is adequate. In this cross-sectional study, lumbar spine and femoral neck BMDs of 151 postmenopausal women aged 50 - 85 years were measured using dual-energy x-ray absorptiometry. Dietary intakes were assessed using a validated food frequency questionnaire. Renal net acid excretion (RNAE), an estimate of acid-base balance, was then calculated indirectly from the diet using the formulae of Remer (based on dietary intakes of protein, phosphorus, potassium, and magnesium; RNAERemer) and Frassetto (based on dietary intakes of protein and potassium; RNAEFrassetto), and was energy adjusted by the residual method. After adjusting for potential confounders, multivariable adjusted means of the lumbar spine BMD of women in the highest tertiles of RNAERemer and RNAEFrassetto were significantly lower than those in the lowest tertiles (for RNAERemer: mean difference -0.084 g/cm2; P=0.007 and for RNAEFrassetto: mean difference - 0.088 g/cm2; P=0.004). Similar results were observed in a subgroup analysis of subjects with dietary calcium intake of >800 mg/day. In conclusion, a higher RNAE (i. e. more dietary acidity), which is associated with greater intake of acid-generating foods and lower intake of alkali-generating foods, may be involved in deteriorating the bone health of postmenopausal Iranian women, even in the context of adequate dietary calcium intake.


2016 ◽  
Vol 24 (3) ◽  
pp. 116-121
Author(s):  
김지용 ◽  
남상욱 ◽  
김영미 ◽  
이윤진 ◽  
이훈상 ◽  
...  

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