Adaptation of cholesterol-requiring NS0 mouse myeloma cells to high density growth in a fully defined protein-free and cholesterol-free culture medium

1995 ◽  
Vol 17 (3) ◽  
pp. 203-211 ◽  
Author(s):  
M. J. Keen ◽  
T. W. Steward
Keyword(s):  
Culture Medium ◽  
High Density ◽  
Myeloma Cells ◽  
Density Growth ◽  
Mouse Myeloma

Elimination of Mycoplasmas from Mouse Myeloma Cells by Intraperitoneal Passage in Mice and by Antibiotic Treatment

Hybridoma ◽  
1989 ◽  
Vol 8 (2) ◽  
pp. 249-257 ◽  
Author(s):  
LOTTA HIRSCHBERG ◽  
GÖRAN BÖLSKE ◽  
TORD HOLME
Keyword(s):  
Antibiotic Treatment ◽  
Myeloma Cells ◽  
Mouse Myeloma

Extinction of expression of immunoglobulin genes in myeloma X fibroblast somatic cell hybrids

1987 ◽  
Vol 7 (2) ◽  
pp. 936-939
Author(s):  
A Greenberg ◽  
R Ber ◽  
Z Kra-Oz ◽  
R Laskov
Keyword(s):  
Light Chain ◽  
Immunoglobulin Genes ◽  
Somatic Cell Hybrids ◽  
Immunoglobulin Production ◽  
Myeloma Cells ◽  
Rna Transcripts ◽  
Processing Level ◽  
Early Processing ◽  
Polypeptide Chains ◽  
Mouse Myeloma

Adherent hybrids between immunoglobulin-producing mouse myeloma cells and fibroblasts do not produce immunoglobulin polypeptide chains. These hybrids retained the actively rearranged immunoglobulin genes of the myeloma parental cells but lacked immunoglobulin heavy- and light-chain RNA transcripts. We conclude that the shutoff of immunoglobulin production in these hybrids occurs at the transcription or early processing level.

Associations Between Cellular Levels of ATP and Prodigiosin Pigment Throughout the Growth Cycle of Serratia marcescens

2021 ◽  
Author(s):  
Pryce L. Haddix
Keyword(s):  
Stationary Phase ◽  
Serratia Marcescens ◽  
Stationary Phases ◽  
Growth Cycle ◽  
High Density ◽  
High Rate ◽  
Lag Phase ◽  
Positive Role ◽  
Atp Production ◽  
Density Growth

ABSTRACT Serratia marcescens is a prolific producer of the red, membrane-associated pigment prodigiosin. Earlier work has established both a positive role for prodigiosin in ATP production during population lag phase and a negative role during high-rate, low cell density growth. This study uses the growth rate and growth phase modulation afforded by chemostat culture to extend prodigiosin functional analysis to the high density and stationary phases. Cellular levels of prodigiosin were positively associated with cellular levels of ATP during high-density growth, and artificial pigment induction during this phase increased cellular ATP. Following peak high density ATP per cell, early stationary phase enabled significant population growth while prodigiosin levels remained high and ATP declined. During late stationary phase, ATP per cell was positively associated with prodigiosin per cell while both declined during continued growth. These results provide correlational evidence for multiple effects of prodigiosin pigment on ATP production throughout the growth cycle. Earlier work and the data presented here enable formulation of a working model for the oscillating relationships between cellular levels of ATP and prodigiosin during batch culture.

scholarly journals Apoptosis of mouse myeloma cells induced by curcumin via the Notch3‑p53 signaling axis

2018 ◽  
Author(s):  
Ying Zhang ◽  
Xin‑Yu Lin ◽  
Jiao‑Hui Zhang ◽  
Zheng‑Lu Xie ◽  
Hui Deng ◽  
...  
Keyword(s):  
Myeloma Cells ◽  
P53 Signaling ◽  
Signaling Axis ◽  
Mouse Myeloma

Subcellular fractionation of mouse myeloma cells

Biochemistry ◽  
1971 ◽  
Vol 10 (4) ◽  
pp. 659-667 ◽  
Author(s):  
Paul M. Knopf ◽  
Yong Sung Choi ◽  
Edwin S. Lennox
Keyword(s):  
Subcellular Fractionation ◽  
Myeloma Cells ◽  
Mouse Myeloma

Nicotinamide-Induced Apoptosis Can Be Enhanced by Melatonin in Mouse Myeloma Cells*

2006 ◽  
Vol 11 (4) ◽  
pp. 408-414 ◽  
Author(s):  
G ZHANG ◽  
H SHENG ◽  
J LIU
Keyword(s):  
Myeloma Cells ◽  
Induced Apoptosis ◽  
Mouse Myeloma

Mutagenesis of Mouse Myeloma Cells with ‘Melphalan’

Nature ◽  
1973 ◽  
Vol 245 (5424) ◽  
pp. 320-322 ◽  
Author(s):  
JEAN-LOUIS PREUD'HOMME ◽  
JOEL BUXBAUM ◽  
MATTHEW D. SCHARFF
Keyword(s):  
Myeloma Cells ◽  
Mouse Myeloma
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