Effect of nociceptive stimulation on mitotic activity of epithelial cells in skin surrounding a wound at different age periods

1977 ◽  
Vol 84 (5) ◽  
pp. 1631-1632
Author(s):  
T. I. Shklyar
Keyword(s):  
Epithelial Cells ◽  
Mitotic Activity ◽  
Nociceptive Stimulation

Influence of pineal indoleamines on the mitotic activity of gastric and colonic mucosa epithelial cells in the rat: Interaction with omeprazole

1991 ◽  
Vol 10 (2) ◽  
pp. 104-108 ◽  
Author(s):  
A. Lewiński ◽  
I. Rybicka ◽  
E. Wajs ◽  
M. Szkudliński ◽  
M. Pawlikowski
Keyword(s):  
Epithelial Cells ◽  
Mitotic Activity ◽  
Colonic Mucosa

MITOTIC ACTIVITY AND RENEWAL RATE OF THE EPITHELIAL CELLS OF HUMAN DUODENUM

1961 ◽  
Vol 45 (4) ◽  
pp. 362-370 ◽  
Author(s):  
Felix D. Bertalanffy ◽  
Katrina P. Nagy
Keyword(s):  
Epithelial Cells ◽  
Mitotic Activity ◽  
Renewal Rate

Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells

2009 ◽  
Vol 126 (1-2) ◽  
pp. 18-29 ◽  
Author(s):  
Hsin-Yi Ho ◽  
Kuo-Hsuan Chang ◽  
Jennifer Nichols ◽  
Meng Li
Keyword(s):  
Epithelial Cells ◽  
Mitotic Activity ◽  
Lens Epithelial Cells ◽  
Homeodomain Protein

scholarly journals Growth pattern of the sex ducts in foetal mouse hermaphrodites

Development ◽  
1983 ◽  
Vol 73 (1) ◽  
pp. 59-68
Author(s):  
C. Yding Andersen ◽  
A. G. Byskov ◽  
J. Grinsted
Keyword(s):  
Epithelial Cells ◽  
Mitotic Activity ◽  
Mitotic Index ◽  
Leydig Cells ◽  
Threshold Level ◽  
Testicular Tissue ◽  
Wolffian Duct ◽  
Maximal Response ◽  
Gonadal Tissue ◽  
Normal Males

In this report the morphology of the gonads and the growth of the Wolffian and Müllerian duct in foetal mouse true hermaphrodites (16 days p.c.) have been studied and compared to that of normal mice. The ducts from the hermaphrodites were placed in one of five groups according to the proportion of male and female characteristic of the gonad. When more than 85 % of the gonadal tissue was masculine, the Wolffian ducts showed the same percentage of cells in mitosis (mitotic index, MI) as normal males. The MI of the Wolffian ducts was lower, but constant, if the gonad contained between 0 and 85 % of testicular tissue. The number of Leydig cells in the gonads showed a linear relationship with the percentage of testicular tissue. Apparently, the MI of the Wolffian duct does not increase with increasing ‘maleness’ and with the number of Leydig cells. Four possibilities are put forward to explain the constant level of MI: (1) The Leydig cells of hermaphrodites may be deficient in producing testosterone. (2) The Leydig cells may produce testosterone at a normal rate but the epithelial cells of the Wolffian duct may not respond to increasing levels of testosterone by increasing their mitotic activity. (3) The presence of female gonadal tissue may directly or indirectly inhibit the mitotic activity of the epithelial cells of the Wolffian duct. (4) The epithelial cells ofthe Wolffian duct may respond to a low threshold level of testosterone, but maximal response is only triggered by a critical higher hormone level present only in group V. In hermaphrodites, the Wolffian duct attached to a gonad without testicular tissue and withoutLeydig cells, has a MI which is significantly higher than in normal females. It is suggested thatcirculating testosterone from the contralateral gonad is responsible for this high MI. In the Müllerian duct a mitotic index similar to that of the normal females was only found when the gonad contained from 0 to 15 % of testicular tissue. If a gonad contained more than 15 % of testicular tissue, the MI of the attached Müllerian duct was much lower equalizing that of normal males. No influence on the growth of the Müllerian duct could be observed from the contralateral gonad.

scholarly journals CYTOLOGICAL ABERRATIONS IN CULTURES OF "NORMAL" MONKEY KIDNEY EPITHELIAL CELLS

1958 ◽  
Vol 107 (4) ◽  
pp. 599-606 ◽  
Author(s):  
Ruth Kleinfeld ◽  
Joseph L. Melnick
Keyword(s):  
Epithelial Cells ◽  
Mitotic Activity ◽  
Primary Cultures ◽  
Mitotic Rate ◽  
Monkey Kidney ◽  
Mitotic Abnormalities ◽  
Normal Monkey ◽  
Dividing Cells ◽  
Chromosome Fragments ◽  
Kidney Epithelial Cells

A cytological study was made of short term primary cultures of monkey kidney epithelial cells grown in serum-containing (M-H) and synthetic (SM-2) media. The mitotic activity of the cultures reached a peak 3 to 5 days after seeding, and rapidly declined if the medium was not changed. With replenishment at 48 hour intervals a high mitotic rate was maintained through the 8th day. Cultures subjected to a glycine- and glucose-deficient medium showed a sharp decline in mitotic activity within 24 hours. When such cultures were replenished a burst of mitotic activity occurred 20 to 30 hours later. Mitotic aberrations such as multipolar spindles, anomalous spindles with scattered chromosomes, lagging or precocious movement of chromosomes, chromosome fragments, and chromosome bridges were found in all cultures ranging from 16 to 40 per cent of the dividing cells. Non-mitotic aberrations such as giant nuclei, multinucleate cells, nuclear fragmentation, micronuclei, nuclear inclusions, and phagocytosis were found in approximately 3 to 7 per cent of the non-dividing cell population. The frequency and types of mitotic abnormalities were generally independent of the medium used and the mitotic index of the cultures.

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