Dynamics of uridine-H3 incorporation into RNA during interphase and role of newly synthesized RNA in formation of the mitotic apparatus in synchronized Chinese hamster cells

1974 ◽  
Vol 77 (1) ◽  
pp. 71-74
Author(s):  
L. S. Strochkova ◽  
V. V. Kazan'ev
Keyword(s):  
Chinese Hamster ◽  
Mitotic Apparatus ◽  
Chinese Hamster Cells

scholarly journals Immunofluorescence analysis of diazepam-induced mitotic apparatus anomalies and chromosome loss in Chinese hamster cells

Mutagenesis ◽  
1998 ◽  
Vol 13 (5) ◽  
pp. 445-452 ◽  
Author(s):  
Massimo Izzo ◽  
Antonio Antoccia ◽  
Francesca Degrassi ◽  
Caterina Tanzarella
Keyword(s):  
Chinese Hamster ◽  
Chromosome Loss ◽  
Immunofluorescence Analysis ◽  
Mitotic Apparatus ◽  
Chinese Hamster Cells

Bioactivation and Toxicity of Two Anthraquinones in V79 Chinese Hamster Cells

1991 ◽  
Vol 19 (1) ◽  
pp. 48-52
Author(s):  
Maurizio Mian ◽  
Duccio Fratta ◽  
Giuseppe Rainaldi ◽  
Dino Benetti ◽  
Pier Giovanni Gervasi
Keyword(s):  
Cytochrome P450 ◽  
Nadh Dehydrogenase ◽  
Chinese Hamster ◽  
Cytochrome P450 Reductase ◽  
V79 Cells ◽  
Chinese Hamster Cells ◽  
P450 Reductase ◽  
Nadph Cytochrome P450 Reductase ◽  
Dt Diaphorase

The role of the flavoprotein NADPH cytochrome P450 reductase, NADH-dehydrogenase and DT-diaphorase in the biotransformation of the anthraquinones rhein and danthron was investigated using purified enzymes, subcellular fractions and cell cultures. The results demonstrated that rhein was more able than danthron to produce O2 by P450 reductase, NADH-dehydrogenase and V79 homogenate and microsomes, and this may explain its higher toxicity to V79 cells. In addition, unlike other quinones, DT-diaphorase appeared not to play a detoxication role in rhein and danthron biotransformation. On the contrary, by inhibiting DT-diaphorase with dicoumarol, the rhein- and danthron-derived cytotoxicity in V79 cells was reduced. This finding suggests that, for these quinones, other coumarol-sensitive biotransformation routes are operative in V79 cells.

Oxidative injury in V79 Chinese hamster cells: protective role of the superoxide dismutase mimetic MnTM-4-PyP

2009 ◽  
Vol 26 (2) ◽  
pp. 91-101 ◽  
Author(s):  
Ana S. Fernandes ◽  
João Serejo ◽  
Jorge Gaspar ◽  
Fátima Cabral ◽  
Ana F. Bettencourt ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Chinese Hamster ◽  
Oxidative Injury ◽  
Protective Role ◽  
Chinese Hamster Cells
Sign in / Sign up

Export Citation Format

Share Document