Quantitative histochemical study of the effect of benzodiazepine tranquilizers on GABA-transaminase activity in the rat brain

1979 ◽  
Vol 87 (2) ◽  
pp. 146-148
Author(s):  
G. �. Galust'yan
Keyword(s):  
Rat Brain ◽  
Histochemical Study ◽  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Benzodiazepine Tranquilizers

Effects of the antidepressant/antipanic drug phenelzine on GABA concentrations and GABA-transaminase activity in rat brain

1992 ◽  
Vol 43 (11) ◽  
pp. 2486-2489 ◽  
Author(s):  
David J. McManus ◽  
Glen B. Baker ◽  
Ian L. Martin ◽  
Andrew J. Greenshaw ◽  
Kevin F. McKenna
Keyword(s):  
Rat Brain ◽  
Transaminase Activity ◽  
Gaba Transaminase

Effect of Pentylentetrazol (PTZ) Kindling on GABAergic System: A Histochemical Study by Staining for GABA-Transaminase (GABA-T)

1993 ◽  
Vol 47 (2) ◽  
pp. 392-393 ◽  
Author(s):  
Toshisaburo Nagai ◽  
Yasuhiro Suzuki ◽  
Hiroshi Arai ◽  
Katsumi Imai ◽  
Ryuhei Kodaka ◽  
...  
Keyword(s):  
Histochemical Study ◽  
Gabaergic System ◽  
Gaba Transaminase ◽  
System A ◽  
Ptz Kindling

Carbaryl-induced elevation of corticosterone level and cholinergic mechanism

1983 ◽  
Vol 3 (10) ◽  
pp. 973-977 ◽  
Author(s):  
S. K. Ray ◽  
M. K. Poddar
Keyword(s):  
Single Dose ◽  
Adrenal Gland ◽  
Rat Brain ◽  
Corticosterone Level ◽  
Acetylcholinesterase Activity ◽  
Plasma Corticosterone ◽  
Significant Rise ◽  
Atropine Sulphate ◽  
Transaminase Activity ◽  
Cholinergic Mechanism

Administration of a single dose (200 mg/kg, p.o.) of carbaryl to rats produced a significant rise in adrenal and plasma corticosterone levels and an increase of tyrosine α-ketoglutarate transaminase activity in the liver cytosot. Synaptosomal acetylcholinesterase activity of the hypothalamic and the striatal regions of rat brain was decreased by carbaryl treatment under similar conditions. Pretreatment (0.5 h) with atropine sulphate (10 mg/kg, i.p.) failed to counteract the carbaryl-induced elevation of adrenal and plasma corticosterone levels and hence the liver tyrosine α-ketoglutarate transaminase activity. Present results suggest that the carbaryl-induced rise in the corticosterone level in the adrenal gland and plasma is not due to a cholinergic mechanism.

In vitro brain GABA-transaminase activity of 1-(4-acetylphenyl)-3-aryloxypyrrolidine-2,5-dione derivatives

2013 ◽  
Vol 6 (4) ◽  
pp. 442-446 ◽  
Author(s):  
Jigarkumar R. Patel ◽  
Bharat Z. Dholakiya ◽  
Nibha Mishra
Keyword(s):  
Transaminase Activity ◽  
Gaba Transaminase ◽  
Brain Gaba
Sign in / Sign up

Export Citation Format

Share Document