Ultrastructural changes in autonomic nerve ganglia in experimental burn trauma

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.

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Basal Lamina Formation in DMBA Induced Mammary Carcinoma

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100080109 ◽

1977 ◽

Vol 35 ◽

pp. 534-535

Author(s):

I. Russo ◽

J. Saby ◽

J. Russo

Keyword(s):

Mammary Carcinoma ◽

Virgin Female ◽

Mammary Glands ◽

Sesame Oil ◽

Female Rats ◽

Ultrastructural Changes ◽

Post Inoculation ◽

Intermediate Type ◽

Sprague Dawley ◽

Intercellular Spaces

It has been previously demonstrated that DMBA-induced rat mammary carcinoma originates in the terminal end bud (TEB) of the mammary gland by proliferation of intermediate type cells (1). The earliest lesion identified is the intraductal proliferation (IDP), which gives rise to intraductal carcinomas. These evolve to cribriform, papillary and comedo types (2). In the present work, we report the ultrastructural changes that take place in the IDP for the formation of a cribriform pattern.Fifty-five-day-old Sprague Dawley virgin female rats were inoculated intra- gastrically with 20 mg 7,12-dimethylbenz(a)anthracene (DMBA) in 1 ml sesame oil. Non-inoculated, age-matched females were used as controls. Mammary glands from both control and experimental rats were removed weekly from the time of inoculation until 86 days post-inoculation. The glands were fixed and processed for electron microscopy (2).The first change observed in IDP's was the widening of intercellular spaces and the secretion of an electron dense material into these spaces (Fig. 1).

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Ultrastructural Changes of the Symbiotic Chlorella-Like Alga Isolated from Hydra Viridis

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100054212 ◽

1982 ◽

Vol 40 ◽

pp. 320-321

Author(s):

K.W. Lee ◽

R.H. Meints ◽

D. Kuczmarski ◽

J.L. Van Etten

Keyword(s):

Time Course ◽

Reciprocal Cross ◽

Ultrastructural Level ◽

Ultrastructural Changes ◽

Symbiotic Relationship ◽

Cell Recognition ◽

Green Hydra ◽

Different Strains ◽

Hydra Viridis

The physiological, biochemical, and ultrastructural aspects of the symbiotic relationship between the Chlorella-like algae and the hydra have been intensively investigated. Reciprocal cross-transfer of the Chlorellalike algae between different strains of green hydra provide a system for the study of cell recognition. However, our attempts to culture the algae free of the host hydra of the Florida strain, Hydra viridis, have been consistently unsuccessful. We were, therefore, prompted to examine the isolated algae at the ultrastructural level on a time course.

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Ultrastructural Changes in Patients With Heat Stroke

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100068047 ◽

1970 ◽

Vol 28 ◽

pp. 210-211

Author(s):

O. T. Minick ◽

M. C. Kew

Keyword(s):

Liver Damage ◽

Heat Stroke ◽

Free State ◽

Ultrastructural Changes ◽

Gold Mines

The effects of heat stroke on hepatic structure were studied in 32 Bantu patients who worked underground in the Transvaal and Orange Free State Gold Mines.Judging from biochemical and morphologic findings, liver damage is an invariable complication of heat stroke. In the milder cases (90 per cent) raised enzyme levels, bromsulphalein retention, and increased prothrombin times were the most common abnormalities.

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